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Trait

Poor concentration

Clinical name: Diminished ability to concentrate

The inability to focus or concentrate on a specific task, activity, or object. The subject may find themselves unable to grasp or understand written text and re-reads frequently without understanding. Familiar tasks or activities are severely compromised due to the lack of ability to concentrate. Thinking through multi-step problems is typically very difficult or impossible, leading to avoidance of such activities.

HPO HP:0031987

Summary

Also called
Concentration problems, Labored thinking, Lack of concentration
Body system
Abnormality of the nervous system

23 condition reports read genes linked to this trait

Dante Labs condition reports look at the genes behind groups of inherited conditions, read from one whole-genome test. Each page says which conditions and genes a report covers, how it is read and what it cannot tell you.

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23 genes linked to Poor concentration

Changes in these genes cause rare conditions in which Poor concentration is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zetaAlwaysIn 1 condition
ADA2adenosine deaminase 2Often (30–79%)In 1 condition
EMC10ER membrane protein complex subunit 10Often (30–79%)In 1 condition
HNRNPCheterogeneous nuclear ribonucleoprotein COften (30–79%)In 1 condition
CMPK2cytidine/uridine monophosphate kinase 2Sometimes (5–29%)In 1 condition
DYMdymeclinSometimes (5–29%)In 1 condition
ERFETS2 repressor factorSometimes (5–29%)In 1 condition
HIVEP2HIVEP zinc finger 2Sometimes (5–29%)In 1 condition
JAM2junctional adhesion molecule 2Sometimes (5–29%)In 1 condition
MYORGmyogenesis regulating glycosidaseSometimes (5–29%)In 1 condition
NAA60N-alpha-acetyltransferase 60, NatF catalytic subunitSometimes (5–29%)In 1 condition
PDGFBplatelet derived growth factor subunit BSometimes (5–29%)In 1 condition
PDGFRBplatelet derived growth factor receptor betaSometimes (5–29%)In 1 condition
RRP12ribosomal RNA processing 12 homologSometimes (5–29%)In 1 condition
SLC20A2solute carrier family 20 member 2Sometimes (5–29%)In 1 condition
TMEM163transmembrane protein 163Sometimes (5–29%)In 1 condition
XPR1xenotropic and polytropic retrovirus receptor 1Sometimes (5–29%)In 1 condition
SPTBN1spectrin beta, non-erythrocytic 1Rarely (1–4%)In 1 condition
HERC2HECT and RLD domain containing E3 ubiquitin protein ligase 2Not recordedIn 1 condition
POLGDNA polymerase gamma, catalytic subunitNot recordedIn 1 condition
TBL1Xtransducin beta like 1 X-linkedNot recordedIn 1 condition
TREX1three prime repair exonuclease 1Not recordedIn 1 condition
TWNKtwinkle mtDNA helicaseNot recordedIn 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Disordered formal thought processReduced attention regulation

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.19-9814e911.

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