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Trait
Involuntary movements
Involuntary contractions of muscle leading to involuntary movements of extremities, neck, trunk, or face.
Summary
- Also called
- Involuntary muscle contractions
- Body system
- Abnormality of the nervous system
Involuntary movementsHP:0004305
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Read the genes linked to Involuntary movements, and the rest of your genome, with one test.
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Get my Genome Test143 genes linked to Involuntary movements
Changes in these genes cause rare conditions in which Involuntary movements is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| DEAF1DEAF1 transcription factor | Always | In 2 conditions |
| MDGA2MAM domain containing glycosylphosphatidylinositol anchor 2 | Always | In 2 conditions |
| SYNJ1synaptojanin 1 | Always | In 3 conditions |
| TWNKtwinkle mtDNA helicase | Always | In 1 condition |
| BAZ1Bbromodomain adjacent to zinc finger domain 1B | Very often (80–99%) | In 1 condition |
| BUD23BUD23 rRNA methyltransferase and ribosome maturation factor | Very often (80–99%) | In 1 condition |
| CDKL5cyclin dependent kinase like 5 | Very often (80–99%) | In 1 condition |
| CLIP2CAP-Gly domain containing linker protein 2 | Very often (80–99%) | In 1 condition |
| DNAJC30DnaJ heat shock protein family (Hsp40) member C30 | Very often (80–99%) | In 1 condition |
| EIF4Heukaryotic translation initiation factor 4H | Very often (80–99%) | In 1 condition |
| ELNelastin | Very often (80–99%) | In 1 condition |
| FKBP6FKBP prolyl isomerase family member 6 (inactive) | Very often (80–99%) | In 1 condition |
| GABBR2gamma-aminobutyric acid type B receptor subunit 2 | Very often (80–99%) | In 2 conditions |
| GTF2Igeneral transcription factor IIi | Very often (80–99%) | In 1 condition |
| GTF2IRD1GTF2I repeat domain containing 1 | Very often (80–99%) | In 1 condition |
| GTF2IRD2GTF2I repeat domain containing 2 | Very often (80–99%) | In 1 condition |
| KCNA1potassium voltage-gated channel subfamily A member 1 | Very often (80–99%) | In 1 condition |
| KCNJ10potassium inwardly rectifying channel subfamily J member 10 | Very often (80–99%) | In 1 condition |
| LIMK1LIM domain kinase 1 | Very often (80–99%) | In 1 condition |
| MECP2methyl-CpG binding protein 2 | Very often (80–99%) | In 2 conditions |
| METTL27methyltransferase like 27 | Very often (80–99%) | In 1 condition |
| NCF1neutrophil cytosolic factor 1 | Very often (80–99%) | In 1 condition |
| NGLY1N-glycanase 1 | Very often (80–99%) | In 1 condition |
| NTNG1netrin G1 | Very often (80–99%) | In 1 condition |
| PRRT2proline rich transmembrane protein 2 | Very often (80–99%) | In 5 conditions |
| RFC2replication factor C subunit 2 | Very often (80–99%) | In 1 condition |
| SMC1Astructural maintenance of chromosomes 1A | Very often (80–99%) | In 1 condition |
| STX1Asyntaxin 1A | Very often (80–99%) | In 1 condition |
| TBL2transducin beta like 2 | Very often (80–99%) | In 1 condition |
| TMEM270transmembrane protein 270 | Very often (80–99%) | In 1 condition |
| VPS13Avacuolar protein sorting 13 homolog A | Very often (80–99%) | In 1 condition |
| VPS37DVPS37D subunit of ESCRT-I | Very often (80–99%) | In 1 condition |
| ADCY5adenylate cyclase 5 | Often (30–79%) | In 1 condition |
| AIFM1apoptosis inducing factor mitochondria associated 1 | Often (30–79%) | In 2 conditions |
| ATN1atrophin 1 | Often (30–79%) | In 1 condition |
| ATP1A2ATPase Na+/K+ transporting subunit alpha 2 | Often (30–79%) | In 2 conditions |
| CABP4calcium binding protein 4 | Often (30–79%) | In 1 condition |
| CACNA1Acalcium voltage-gated channel subunit alpha1 A | Often (30–79%) | In 2 conditions |
| CEP85Lcentrosomal protein 85L | Often (30–79%) | In 1 condition |
| CHRNA2cholinergic receptor nicotinic alpha 2 subunit | Often (30–79%) | In 1 condition |
Show 103 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| CHRNA4cholinergic receptor nicotinic alpha 4 subunit | Often (30–79%) | In 1 condition |
| CHRNB2cholinergic receptor nicotinic beta 2 subunit | Often (30–79%) | In 1 condition |
| CPceruloplasmin | Often (30–79%) | In 1 condition |
| CRHcorticotropin releasing hormone | Often (30–79%) | In 1 condition |
| DEPDC5DEP domain containing 5, GATOR1 subcomplex subunit | Often (30–79%) | In 2 conditions |
| DNAJC6DnaJ heat shock protein family (Hsp40) member C6 | Often (30–79%) | In 1 condition |
| DNM1dynamin 1 | Often (30–79%) | In 2 conditions |
| FTLferritin light chain | Often (30–79%) | In 1 condition |
| GRIK2glutamate ionotropic receptor kainate type subunit 2 | Often (30–79%) | In 1 condition |
| GRIN1glutamate ionotropic receptor NMDA type subunit 1 | Often (30–79%) | In 1 condition |
| HPCAhippocalcin | Often (30–79%) | In 1 condition |
| HTThuntingtin | Often (30–79%) | In 1 condition |
| IARS2isoleucyl-tRNA synthetase 2, mitochondrial | Often (30–79%) | In 1 condition |
| KCNQ2potassium voltage-gated channel subfamily Q member 2 | Often (30–79%) | In 1 condition |
| KCNQ3potassium voltage-gated channel subfamily Q member 3 | Often (30–79%) | In 1 condition |
| KCNT1potassium sodium-activated channel subfamily T member 1 | Often (30–79%) | In 1 condition |
| MACF1microtubule actin crosslinking factor 1 | Often (30–79%) | In 2 conditions |
| MAPTmicrotubule associated protein tau | Often (30–79%) | In 1 condition |
| MICU1mitochondrial calcium uptake 1 | Often (30–79%) | In 1 condition |
| PGAP3post-GPI attachment to proteins phospholipase 3 | Often (30–79%) | In 1 condition |
| PNKDPNKD metallo-beta-lactamase domain containing | Often (30–79%) | In 1 condition |
| PODXLpodocalyxin like | Often (30–79%) | In 1 condition |
| PRNPprion protein (Kanno blood group) | Often (30–79%) | In 1 condition |
| SCN1Asodium voltage-gated channel alpha subunit 1 | Often (30–79%) | In 2 conditions |
| SCN2Asodium voltage-gated channel alpha subunit 2 | Often (30–79%) | In 1 condition |
| SCN8Asodium voltage-gated channel alpha subunit 8 | Often (30–79%) | In 2 conditions |
| SLC2A1solute carrier family 2 member 1 | Often (30–79%) | In 1 condition |
| SLC2A3solute carrier family 2 member 3 | Often (30–79%) | In 1 condition |
| TANGO2transport and golgi organization 2 homolog | Often (30–79%) | In 1 condition |
| TBPTATA-box binding protein | Often (30–79%) | In 1 condition |
| TMEM151Atransmembrane protein 151A | Often (30–79%) | In 1 condition |
| AARS1alanyl-tRNA synthetase 1 | Sometimes (5–29%) | In 1 condition |
| ACTL6Bactin like 6B | Sometimes (5–29%) | In 1 condition |
| AP3B2adaptor related protein complex 3 subunit beta 2 | Sometimes (5–29%) | In 1 condition |
| ATP1A3ATPase Na+/K+ transporting subunit alpha 3 | Sometimes (5–29%) | In 1 condition |
| ATP6V1AATPase H+ transporting V1 subunit A | Sometimes (5–29%) | In 1 condition |
| CACNA1Bcalcium voltage-gated channel subunit alpha1 B | Sometimes (5–29%) | In 1 condition |
| CACNA2D1calcium voltage-gated channel auxiliary subunit alpha2delta 1 | Sometimes (5–29%) | In 1 condition |
| CAMK2Acalcium/calmodulin dependent protein kinase II alpha | Sometimes (5–29%) | In 1 condition |
| CARS2cysteinyl-tRNA synthetase 2, mitochondrial | Sometimes (5–29%) | In 1 condition |
| CDK19cyclin dependent kinase 19 | Sometimes (5–29%) | In 1 condition |
| CELF2CUGBP Elav-like family member 2 | Sometimes (5–29%) | In 1 condition |
| CHMP1Acharged multivesicular body protein 1A | Sometimes (5–29%) | In 1 condition |
| CLTCclathrin heavy chain | Sometimes (5–29%) | In 1 condition |
| CMPK2cytidine/uridine monophosphate kinase 2 | Sometimes (5–29%) | In 1 condition |
| CNKSR2connector enhancer of kinase suppressor of Ras 2 | Sometimes (5–29%) | In 1 condition |
| CYFIP2cytoplasmic FMR1 interacting protein 2 | Sometimes (5–29%) | In 1 condition |
| DALRD3DALR anticodon binding domain containing 3 | Sometimes (5–29%) | In 1 condition |
| DHDDSdehydrodolichyl diphosphate synthase subunit | Sometimes (5–29%) | In 1 condition |
| EEF1A2eukaryotic translation elongation factor 1 alpha 2 | Sometimes (5–29%) | In 1 condition |
| FBXO28F-box protein 28 | Sometimes (5–29%) | In 1 condition |
| FGF12fibroblast growth factor 12 | Sometimes (5–29%) | In 1 condition |
| FOXG1forkhead box G1 | Sometimes (5–29%) | In 1 condition |
| FZR1fizzy and cell division cycle 20 related 1 | Sometimes (5–29%) | In 1 condition |
| GABRA2gamma-aminobutyric acid type A receptor subunit alpha2 | Sometimes (5–29%) | In 1 condition |
| GABRA5gamma-aminobutyric acid type A receptor subunit alpha5 | Sometimes (5–29%) | In 1 condition |
| GABRB2gamma-aminobutyric acid type A receptor subunit beta2 | Sometimes (5–29%) | In 1 condition |
| GABRG2gamma-aminobutyric acid type A receptor subunit gamma2 | Sometimes (5–29%) | In 1 condition |
| GFM2GTP dependent ribosome recycling factor mitochondrial 2 | Sometimes (5–29%) | In 2 conditions |
| GNASGNAS complex locus | Sometimes (5–29%) | In 1 condition |
| GRIN2Dglutamate ionotropic receptor NMDA type subunit 2D | Sometimes (5–29%) | In 1 condition |
| HCN1hyperpolarization activated cyclic nucleotide gated potassium channel 1 | Sometimes (5–29%) | In 1 condition |
| JAM2junctional adhesion molecule 2 | Sometimes (5–29%) | In 1 condition |
| JPH3junctophilin 3 | Sometimes (5–29%) | In 1 condition |
| KCNA2potassium voltage-gated channel subfamily A member 2 | Sometimes (5–29%) | In 1 condition |
| KCNB1potassium voltage-gated channel subfamily B member 1 | Sometimes (5–29%) | In 1 condition |
| KCNC2potassium voltage-gated channel subfamily C member 2 | Sometimes (5–29%) | In 1 condition |
| KCNH5potassium voltage-gated channel subfamily H member 5 | Sometimes (5–29%) | In 1 condition |
| LIG3DNA ligase 3 | Sometimes (5–29%) | In 1 condition |
| MYORGmyogenesis regulating glycosidase | Sometimes (5–29%) | In 1 condition |
| NAA60N-alpha-acetyltransferase 60, NatF catalytic subunit | Sometimes (5–29%) | In 1 condition |
| NECAP1NECAP endocytosis associated 1 | Sometimes (5–29%) | In 1 condition |
| NKX2-1NK2 homeobox 1 | Sometimes (5–29%) | In 1 condition |
| NTRK2neurotrophic receptor tyrosine kinase 2 | Sometimes (5–29%) | In 1 condition |
| NUS1NUS1 dehydrodolichyl diphosphate synthase subunit | Sometimes (5–29%) | In 1 condition |
| PACS2phosphofurin acidic cluster sorting protein 2 | Sometimes (5–29%) | In 1 condition |
| PARS2prolyl-tRNA synthetase 2, mitochondrial | Sometimes (5–29%) | In 1 condition |
| PDGFBplatelet derived growth factor subunit B | Sometimes (5–29%) | In 1 condition |
| PDGFRBplatelet derived growth factor receptor beta | Sometimes (5–29%) | In 1 condition |
| PPP3CAprotein phosphatase 3 catalytic subunit alpha | Sometimes (5–29%) | In 1 condition |
| RRP12ribosomal RNA processing 12 homolog | Sometimes (5–29%) | In 1 condition |
| SCN3Asodium voltage-gated channel alpha subunit 3 | Sometimes (5–29%) | In 1 condition |
| SLC13A5solute carrier family 13 member 5 | Sometimes (5–29%) | In 2 conditions |
| SLC1A2solute carrier family 1 member 2 | Sometimes (5–29%) | In 1 condition |
| SLC20A2solute carrier family 20 member 2 | Sometimes (5–29%) | In 1 condition |
| SLC38A3solute carrier family 38 member 3 | Sometimes (5–29%) | In 1 condition |
| SMSspermine synthase | Sometimes (5–29%) | In 1 condition |
| SYNGAP1synaptic Ras GTPase activating protein 1 | Sometimes (5–29%) | In 1 condition |
| SZT2SZT2 subunit of KICSTOR complex | Sometimes (5–29%) | In 1 condition |
| TOE1target of EGR1, exonuclease | Sometimes (5–29%) | In 1 condition |
| TRAK1trafficking kinesin protein 1 | Sometimes (5–29%) | In 1 condition |
| TUBB4Atubulin beta 4A class IVa | Sometimes (5–29%) | In 1 condition |
| UBA5ubiquitin like modifier activating enzyme 5 | Sometimes (5–29%) | In 1 condition |
| UFSP2UFM1 specific peptidase 2 | Sometimes (5–29%) | In 1 condition |
| XPR1xenotropic and polytropic retrovirus receptor 1 | Sometimes (5–29%) | In 2 conditions |
| YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma | Sometimes (5–29%) | In 1 condition |
| ZFXzinc finger protein X-linked | Sometimes (5–29%) | In 1 condition |
| DHX30DExH-box helicase 30 | Not recorded | In 1 condition |
| GNAO1G protein subunit alpha o1 | Not recorded | In 1 condition |
| GPR88G protein-coupled receptor 88 | Not recorded | In 1 condition |
| MECRmitochondrial trans-2-enoyl-CoA reductase | Not recorded | In 1 condition |
| PRKRAprotein activator of interferon induced protein kinase EIF2AK2 | Not recorded | In 1 condition |
| SYT1synaptotagmin 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
- Tremor495 genes
- Jerking352 genes
- Chorea189 genes
- Clonus98 genes
- Muscle twitch91 genes
- Involuntary writhing movements in fingers, hands, toes, and feet69 genes
- Paroxysmal dyskinesia22 genes
- Alien limb phenomenon4 genes
- Hemiballismus4 genes
- Akathisia1 gene
- Chvostek sign1 gene
- Self-mutilation of tongue and lips due to involuntary movements1 gene
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Who We HelpOur ScienceProductsOutcomes
Log InAskGet Startedfrom $449
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks