Trait
Clumsiness
Lack of physical coordination resulting in an abnormal tendency to drop items or bump into objects.
Summary
- Body system
- Abnormality of the nervous system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test102 genes linked to Clumsiness
Changes in these genes cause rare conditions in which Clumsiness is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| AQP4aquaporin 4 | Always | In 2 conditions |
| CHD8chromodomain helicase DNA binding protein 8 | Always | In 1 condition |
| CWF19L1CWF19 like cell cycle control factor 1 | Always | In 2 conditions |
| DNM1Ldynamin 1L | Always | In 1 condition |
| FDXRferredoxin reductase | Always | In 1 condition |
| GPRC5BG protein-coupled receptor class C group 5 member B | Always | In 2 conditions |
| HAX1HCLS1 associated protein X-1 | Always | In 1 condition |
| LRRC7leucine rich repeat containing 7 | Always | In 1 condition |
| MICU1mitochondrial calcium uptake 1 | Always | In 1 condition |
| MSL2MSL complex subunit 2 | Always | In 1 condition |
| PAK3p21 (RAC1) activated kinase 3 | Always | In 1 condition |
| PDHA1pyruvate dehydrogenase E1 subunit alpha 1 | Always | In 1 condition |
| PPP2R5Cprotein phosphatase 2 regulatory subunit B'gamma | Always | In 1 condition |
| RAB32RAB32, member RAS oncogene family | Always | In 1 condition |
| SPTAN1spectrin alpha, non-erythrocytic 1 | Always | In 1 condition |
| TTPAalpha tocopherol transfer protein | Always | In 2 conditions |
| ATP7BATPase copper transporting beta | Very often (80–99%) | In 1 condition |
| BCKDKbranched chain keto acid dehydrogenase kinase | Very often (80–99%) | In 1 condition |
| SLC22A5solute carrier family 22 member 5 | Very often (80–99%) | In 1 condition |
| UBE3Aubiquitin protein ligase E3A | Very often (80–99%) | In 1 condition |
| AASSaminoadipate-semialdehyde synthase | Often (30–79%) | In 2 conditions |
| ACTA1actin alpha 1, skeletal muscle | Often (30–79%) | In 1 condition |
| AFF2ALF transcription elongation factor 2 | Often (30–79%) | In 1 condition |
| ARSAarylsulfatase A | Often (30–79%) | In 3 conditions |
| ASAH1N-acylsphingosine amidohydrolase 1 | Often (30–79%) | In 1 condition |
| ATP2B3ATPase plasma membrane Ca2+ transporting 3 | Often (30–79%) | In 1 condition |
| ATXN3ataxin 3 | Often (30–79%) | In 3 conditions |
| CAPN3calpain 3 | Often (30–79%) | In 1 condition |
| CLN8CLN8 transmembrane ER and ERGIC protein | Often (30–79%) | In 2 conditions |
| DARS2aspartyl-tRNA synthetase 2, mitochondrial | Often (30–79%) | In 1 condition |
| DCCDCC netrin 1 receptor | Often (30–79%) | In 1 condition |
| DNAL4dynein axonemal light chain 4 | Often (30–79%) | In 1 condition |
| FXNfrataxin | Often (30–79%) | In 1 condition |
| GALCgalactosylceramidase | Often (30–79%) | In 2 conditions |
| GJB1gap junction protein beta 1 | Often (30–79%) | In 1 condition |
| HEPACAMhepatic and glial cell adhesion molecule | Often (30–79%) | In 2 conditions |
| HNRNPA1heterogeneous nuclear ribonucleoprotein A1 | Often (30–79%) | In 2 conditions |
| HTThuntingtin | Often (30–79%) | In 1 condition |
| KBTBD13kelch repeat and BTB domain containing 13 | Often (30–79%) | In 1 condition |
| KCNA1potassium voltage-gated channel subfamily A member 1 | Often (30–79%) | In 1 condition |
Show 62 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| KLHL41kelch like family member 41 | Often (30–79%) | In 1 condition |
| MPZmyelin protein zero | Often (30–79%) | In 1 condition |
| MYPNmyopalladin | Often (30–79%) | In 1 condition |
| NEBnebulin | Often (30–79%) | In 1 condition |
| NR4A2nuclear receptor subfamily 4 group A member 2 | Often (30–79%) | In 1 condition |
| NTN1netrin 1 | Often (30–79%) | In 1 condition |
| PLA2G6phospholipase A2 group VI | Often (30–79%) | In 2 conditions |
| PMP22peripheral myelin protein 22 | Often (30–79%) | In 1 condition |
| POLR3ARNA polymerase III subunit A | Often (30–79%) | In 1 condition |
| PRNPprion protein (Kanno blood group) | Often (30–79%) | In 2 conditions |
| PSAPprosaposin | Often (30–79%) | In 3 conditions |
| RAD51RAD51 recombinase | Often (30–79%) | In 1 condition |
| SCO2synthesis of cytochrome C oxidase 2 | Often (30–79%) | In 1 condition |
| SDHAsuccinate dehydrogenase complex flavoprotein subunit A | Often (30–79%) | In 1 condition |
| SKOR2SKI family transcriptional corepressor 2 | Often (30–79%) | In 1 condition |
| SLC2A3solute carrier family 2 member 3 | Often (30–79%) | In 1 condition |
| SQSTM1sequestosome 1 | Often (30–79%) | In 1 condition |
| TIA1TIA1 cytotoxic granule associated RNA binding protein | Often (30–79%) | In 1 condition |
| TPM2tropomyosin 2 | Often (30–79%) | In 1 condition |
| TPM3tropomyosin 3 | Often (30–79%) | In 1 condition |
| TPP1tripeptidyl peptidase 1 | Often (30–79%) | In 2 conditions |
| ALG13ALG13 UDP-N-acetylglucosaminyltransferase subunit | Sometimes (5–29%) | In 1 condition |
| BSNDbarttin CLCNK type accessory subunit beta | Sometimes (5–29%) | In 1 condition |
| CACHD1cache domain containing 1 | Sometimes (5–29%) | In 1 condition |
| CAV3caveolin 3 | Sometimes (5–29%) | In 1 condition |
| CLCN1chloride voltage-gated channel 1 | Sometimes (5–29%) | In 1 condition |
| CLCNKAchloride voltage-gated channel Ka | Sometimes (5–29%) | In 1 condition |
| CLCNKBchloride voltage-gated channel Kb | Sometimes (5–29%) | In 1 condition |
| CLTCclathrin heavy chain | Sometimes (5–29%) | In 1 condition |
| CMPK2cytidine/uridine monophosphate kinase 2 | Sometimes (5–29%) | In 1 condition |
| DEAF1DEAF1 transcription factor | Sometimes (5–29%) | In 1 condition |
| GALTgalactose-1-phosphate uridylyltransferase | Sometimes (5–29%) | In 1 condition |
| GRIN2Aglutamate ionotropic receptor NMDA type subunit 2A | Sometimes (5–29%) | In 1 condition |
| JAM2junctional adhesion molecule 2 | Sometimes (5–29%) | In 1 condition |
| KCNC3potassium voltage-gated channel subfamily C member 3 | Sometimes (5–29%) | In 1 condition |
| KDM4Blysine demethylase 4B | Sometimes (5–29%) | In 1 condition |
| MAN2B1mannosidase alpha class 2B member 1 | Sometimes (5–29%) | In 2 conditions |
| MAPTmicrotubule associated protein tau | Sometimes (5–29%) | In 1 condition |
| MECRmitochondrial trans-2-enoyl-CoA reductase | Sometimes (5–29%) | In 1 condition |
| MLC1modulator of VRAC current 1 | Sometimes (5–29%) | In 1 condition |
| MORC2MORC family CW-type zinc finger 2 | Sometimes (5–29%) | In 1 condition |
| MYORGmyogenesis regulating glycosidase | Sometimes (5–29%) | In 1 condition |
| NAA60N-alpha-acetyltransferase 60, NatF catalytic subunit | Sometimes (5–29%) | In 1 condition |
| NKX2-1NK2 homeobox 1 | Sometimes (5–29%) | In 1 condition |
| PDGFBplatelet derived growth factor subunit B | Sometimes (5–29%) | In 1 condition |
| PDGFRBplatelet derived growth factor receptor beta | Sometimes (5–29%) | In 1 condition |
| RNF125ring finger protein 125 | Sometimes (5–29%) | In 1 condition |
| RNF168ring finger protein 168 | Sometimes (5–29%) | In 1 condition |
| RRP12ribosomal RNA processing 12 homolog | Sometimes (5–29%) | In 1 condition |
| SLC20A2solute carrier family 20 member 2 | Sometimes (5–29%) | In 1 condition |
| SLC39A14solute carrier family 39 member 14 | Sometimes (5–29%) | In 1 condition |
| SYNE1spectrin repeat containing nuclear envelope protein 1 | Sometimes (5–29%) | In 1 condition |
| TSHBthyroid stimulating hormone subunit beta | Sometimes (5–29%) | In 1 condition |
| TTNtitin | Sometimes (5–29%) | In 1 condition |
| XPR1xenotropic and polytropic retrovirus receptor 1 | Sometimes (5–29%) | In 1 condition |
| ALDH3A2aldehyde dehydrogenase 3 family member A2 | Rarely (1–4%) | In 1 condition |
| PANK2pantothenate kinase 2 | Rarely (1–4%) | In 1 condition |
| ACOX1acyl-CoA oxidase 1 | Not recorded | In 1 condition |
| CLN5CLN5 lysosomal BMP synthase | Not recorded | In 1 condition |
| SLC52A2solute carrier family 52 member 2 | Not recorded | In 1 condition |
| SLC52A3solute carrier family 52 member 3 | Not recorded | In 1 condition |
| TWNKtwinkle mtDNA helicase | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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