Trait
Pit in front of the ear
Clinical name: Preauricular pit
Small indentation anterior to the insertion of the ear.
Summary
- Also called
- Ear pit, Preauricular earpits, Preauricular fistulas, Preauricular pits, Preauricular sinus
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Pit in front of the ear, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test66 genes linked to Pit in front of the ear
Changes in these genes cause rare conditions in which Pit in front of the ear is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| EYA1EYA transcriptional coactivator and phosphatase 1 | Always | In 5 conditions |
| FGFR2fibroblast growth factor receptor 2 | Always | In 1 condition |
| H4C9H4 clustered histone 9 | Always | In 1 condition |
| PAX1paired box 1 | Always | In 1 condition |
| SPECC1Lsperm antigen with calponin homology and coiled-coil domains 1 like | Always | In 2 conditions |
| STAG2STAG2 cohesin complex component | Always | In 1 condition |
| MED12mediator complex subunit 12 | Very often (80–99%) | In 2 conditions |
| PPP2R3Cprotein phosphatase 2 regulatory subunit B''gamma | Very often (80–99%) | In 1 condition |
| SIX1SIX homeobox 1 | Very often (80–99%) | In 5 conditions |
| SIX5SIX homeobox 5 | Very often (80–99%) | In 2 conditions |
| TFAP2Atranscription factor AP-2 alpha | Very often (80–99%) | In 2 conditions |
| ANK1ankyrin 1 | Often (30–79%) | In 1 condition |
| B3GLCTbeta 3-glucosyltransferase | Often (30–79%) | In 2 conditions |
| CITED2Cbp/p300 interacting transactivator with ED-rich tail 2 | Often (30–79%) | In 1 condition |
| CPLX1complexin 1 | Often (30–79%) | In 2 conditions |
| CTBP1C-terminal binding protein 1 | Often (30–79%) | In 2 conditions |
| DICER1dicer 1, ribonuclease III | Often (30–79%) | In 1 condition |
| FGFRL1fibroblast growth factor receptor like 1 | Often (30–79%) | In 1 condition |
| FLT4fms related receptor tyrosine kinase 4 | Often (30–79%) | In 1 condition |
| GATA4GATA binding protein 4 | Often (30–79%) | In 2 conditions |
| GATA5GATA binding protein 5 | Often (30–79%) | In 1 condition |
| GATA6GATA binding protein 6 | Often (30–79%) | In 2 conditions |
| GDF1growth differentiation factor 1 | Often (30–79%) | In 1 condition |
| GJA5gap junction protein alpha 5 | Often (30–79%) | In 1 condition |
| GSCgoosecoid homeobox | Often (30–79%) | In 1 condition |
| HYAL2hyaluronidase 2 | Often (30–79%) | In 1 condition |
| JAG1jagged canonical Notch ligand 1 | Often (30–79%) | In 2 conditions |
| KDM6Alysine demethylase 6A | Often (30–79%) | In 1 condition |
| KDRkinase insert domain receptor | Often (30–79%) | In 1 condition |
| KMT2Dlysine methyltransferase 2D | Often (30–79%) | In 2 conditions |
| LETM1leucine zipper and EF-hand containing transmembrane protein 1 | Often (30–79%) | In 2 conditions |
| MITFmelanocyte inducing transcription factor | Often (30–79%) | In 1 condition |
| NELFAnegative elongation factor complex member A | Often (30–79%) | In 1 condition |
| NKX2-5NK2 homeobox 5 | Often (30–79%) | In 2 conditions |
| NKX2-6NK2 homeobox 6 | Often (30–79%) | In 1 condition |
| NPHP3nephrocystin 3 | Often (30–79%) | In 1 condition |
| NSD2nuclear receptor binding SET domain protein 2 | Often (30–79%) | In 2 conditions |
| PIGGphosphatidylinositol glycan anchor biosynthesis class G (EMM blood group) | Often (30–79%) | In 1 condition |
| TBX1T-box transcription factor 1 | Often (30–79%) | In 2 conditions |
| ZFPM2zinc finger protein, FOG family member 2 | Often (30–79%) | In 2 conditions |
Show 26 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| BRPF1bromodomain and PHD finger containing 1 | Sometimes (5–29%) | In 1 condition |
| CRELD1CRELD disulfide isomerase 1 | Sometimes (5–29%) | In 1 condition |
| EDNRAendothelin receptor type A | Sometimes (5–29%) | In 1 condition |
| FBXO11F-box protein 11 | Sometimes (5–29%) | In 1 condition |
| FLNAfilamin A | Sometimes (5–29%) | In 1 condition |
| FRYLFRY like transcription coactivator | Sometimes (5–29%) | In 1 condition |
| HK1hexokinase 1 | Sometimes (5–29%) | In 1 condition |
| HNRNPKheterogeneous nuclear ribonucleoprotein K | Sometimes (5–29%) | In 2 conditions |
| KAT6Alysine acetyltransferase 6A | Sometimes (5–29%) | In 1 condition |
| MED16mediator complex subunit 16 | Sometimes (5–29%) | In 1 condition |
| MID1midline 1 | Sometimes (5–29%) | In 1 condition |
| POLR1DRNA polymerase I and III subunit D | Sometimes (5–29%) | In 1 condition |
| PPP1CBprotein phosphatase 1 catalytic subunit beta | Sometimes (5–29%) | In 1 condition |
| REREarginine-glutamic acid dipeptide repeats | Sometimes (5–29%) | In 1 condition |
| SEPHS1selenophosphate synthetase 1 | Sometimes (5–29%) | In 1 condition |
| SETD5SET domain containing 5 | Sometimes (5–29%) | In 1 condition |
| TRPM3transient receptor potential cation channel subfamily M member 3 | Sometimes (5–29%) | In 1 condition |
| UBE2Aubiquitin conjugating enzyme E2 A | Sometimes (5–29%) | In 1 condition |
| WBP11WW domain binding protein 11 | Sometimes (5–29%) | In 1 condition |
| XYLT2xylosyltransferase 2 | Sometimes (5–29%) | In 1 condition |
| ZNF462zinc finger protein 462 | Rarely (1–4%) | In 1 condition |
| EIF2AK3eukaryotic translation initiation factor 2 alpha kinase 3 | Not recorded | In 1 condition |
| GPC3glypican 3 | Not recorded | In 1 condition |
| KCNJ2potassium inwardly rectifying channel subfamily J member 2 | Not recorded | In 1 condition |
| RAB23RAB23, member RAS oncogene family | Not recorded | In 1 condition |
| SALL1spalt like transcription factor 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks