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Gene

PPP2R3C

protein phosphatase 2 regulatory subunit B''gamma

Summary

Cytogenetic location
14q13.2
Coordinates
Chromosome 14: 35,085,472–35,121,990 (GRCh38)
Exons
13 exons across 36.5 kb
Protein
453 amino acids
Also known as
FLJ20644, G4-1, G5PR
Previous symbols
C14orf10
MANE Select transcript
ENST00000261475.10NM_017917.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads PPP2R3C yet. The test sequences your whole genome, so your data includes it all the same.

How PPP2R3C is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 14, with a bracket where PPP2R3C sits. PPP2R3C and 11 genes near it on chromosome 14, from 34,603,731 to 35,603,730.Chromosome 1414q13.2p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.11q32.12q32.13q32.2q32.31q32.32q32.3334.8 Mb35 Mb35.2 Mb35.4 Mb35.6 MbSNX6: 34,561,093–34,630,208, reverse strandSNX6CFL2: 34,707,001–34,714,946, reverse strandCFL2BAZ1A: 34,752,028–34,875,647, reverse strandBAZ1ASRP54: 34,981,957–35,029,686, forward strandSRP54FAM177A1: 35,045,117–35,116,630, forward strandFAM177A1PPP2R3C: 35,085,472–35,121,990, reverse strandPPP2R3CPRORP: 35,121,842–35,278,538, forward strandPRORP: 35,122,549–35,317,474, forward strandPSMA6: 35,278,596–35,318,734, forward strandPSMA6NFKBIA: 35,401,079–35,404,749, reverse strandNFKBIAINSM2: 35,534,164–35,537,054, forward strandINSM2RALGAPA1: 35,538,352–35,809,325, reverse strandRALGAPA1Diagram of PPP2R3C: 13 exons on the reverse strand of chromosome 14Exon 11: 1 known disease-causing siteExon 7: 1 known disease-causing siteExon 4: 1 known disease-causing siteExon 13: 35,085,472–35,085,778, 307 basesExon 12: 35,087,951–35,088,010, 60 basesExon 11: 35,091,070–35,091,207, 138 basesExon 10: 35,095,048–35,095,184, 137 basesExon 9: 35,096,558–35,096,633, 76 basesExon 8: 35,096,709–35,096,764, 56 basesExon 7: 35,099,252–35,099,384, 133 basesExon 6: 35,107,304–35,107,374, 71 basesExon 5: 35,108,139–35,108,236, 98 basesExon 4: 35,109,819–35,109,931, 113 basesExon 3: 35,110,525–35,110,629, 105 basesExon 2: 35,116,610–35,116,737, 128 basesExon 1: 35,121,902–35,121,990, 89 bases131210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.5 kb of the gene's 36.5 kb; 1,362 of those bases code for the protein.

How a genome test reads PPP2R3C

4

positions in PPP2R3C where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 36.5 kb of PPP2R3C, introns included, not only the 1.5 kb of exons.

Traits linked to PPP2R3C

The Human Phenotype Ontology lists these as features of the rare conditions PPP2R3C can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). PPP2R3C gene: protein phosphatase 2 regulatory subunit B''gamma. Retrieved 17 October 2026, from https://dantelabs.com/genes/ppp2r3c

Vancouver

Dante Labs. PPP2R3C gene: protein phosphatase 2 regulatory subunit B''gamma [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/ppp2r3c

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