Trait
Failure of development of more than six teeth
Clinical name: Oligodontia
The absence of six or more teeth from the normal series by a failure to develop.
Summary
- Also called
- Missing more than six teeth, Number of teeth decreased by more than six, Partial anodontia
- Body system
- Abnormality of head or neck
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Failure of development of more than six teeth, and the rest of your genome, with one test.
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Get my Genome Test70 genes linked to Failure of development of more than six teeth
Changes in these genes cause rare conditions in which Failure of development of more than six teeth is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| AXIN2axin 2 | Always | In 1 condition |
| DVL1dishevelled segment polarity protein 1 | Always | In 2 conditions |
| EDAectodysplasin A | Always | In 2 conditions |
| EDARectodysplasin A receptor | Always | In 1 condition |
| EDARADDEDAR associated via death domain | Always | In 3 conditions |
| FGFR1fibroblast growth factor receptor 1 | Always | In 1 condition |
| GREM2gremlin 2, DAN family BMP antagonist | Always | In 1 condition |
| IRF6interferon regulatory factor 6 | Always | In 1 condition |
| KDM6Alysine demethylase 6A | Always | In 1 condition |
| KMT2Dlysine methyltransferase 2D | Always | In 1 condition |
| KREMEN1kringle containing transmembrane protein 1 | Always | In 1 condition |
| LRP6LDL receptor related protein 6 | Always | In 1 condition |
| LTBP3latent transforming growth factor beta binding protein 3 | Always | In 1 condition |
| MSX1msh homeobox 1 | Always | In 1 condition |
| PAX9paired box 9 | Always | In 2 conditions |
| PITX2paired like homeodomain 2 | Always | In 1 condition |
| POLR3GLRNA polymerase III subunit GL | Always | In 1 condition |
| PTH1Rparathyroid hormone 1 receptor | Always | In 1 condition |
| SMOC2SPARC related modular calcium binding 2 | Always | In 1 condition |
| SUMO1small ubiquitin like modifier 1 | Always | In 1 condition |
| TGFAtransforming growth factor alpha | Always | In 1 condition |
| TSPEARthrombospondin type laminin G domain and EAR repeats | Always | In 1 condition |
| WNT10AWnt family member 10A | Always | In 1 condition |
| WNT10BWnt family member 10B | Always | In 1 condition |
| FLNAfilamin A | Very often (80–99%) | In 3 conditions |
| SLC25A24solute carrier family 25 member 24 | Very often (80–99%) | In 2 conditions |
| ANKRD11ankyrin repeat domain 11 | Often (30–79%) | In 2 conditions |
| ATP6V1B2ATPase H+ transporting V1 subunit B2 | Often (30–79%) | In 1 condition |
| BCL11BBCL11 transcription factor B | Often (30–79%) | In 1 condition |
| BCORBCL6 corepressor | Often (30–79%) | In 2 conditions |
| CLDN1claudin 1 | Often (30–79%) | In 2 conditions |
| LEF1lymphoid enhancer binding factor 1 | Often (30–79%) | In 1 condition |
| MAFMAF bZIP transcription factor | Often (30–79%) | In 1 condition |
| PIK3C2Aphosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha | Often (30–79%) | In 2 conditions |
| POLR3ARNA polymerase III subunit A | Often (30–79%) | In 2 conditions |
| POLR3BRNA polymerase III subunit B | Often (30–79%) | In 2 conditions |
| RMP64ribonuclease MRP subunit p64 | Often (30–79%) | In 1 condition |
| SH3BP2SH3 domain binding protein 2 | Often (30–79%) | In 2 conditions |
| UBR1ubiquitin protein ligase E3 component n-recognin 1 | Often (30–79%) | In 1 condition |
| ADNPactivity dependent neuroprotector homeobox | Sometimes (5–29%) | In 1 condition |
Show 30 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| CEP152centrosomal protein 152 | Sometimes (5–29%) | In 1 condition |
| CHSY1chondroitin sulfate synthase 1 | Sometimes (5–29%) | In 1 condition |
| CUX1cut like homeobox 1 | Sometimes (5–29%) | In 1 condition |
| DVL3dishevelled segment polarity protein 3 | Sometimes (5–29%) | In 1 condition |
| FZD2frizzled class receptor 2 | Sometimes (5–29%) | In 1 condition |
| HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 | Sometimes (5–29%) | In 1 condition |
| IKBKGinhibitor of nuclear factor kappa B kinase regulatory subunit gamma | Sometimes (5–29%) | In 1 condition |
| KCNJ2potassium inwardly rectifying channel subfamily J member 2 | Sometimes (5–29%) | In 2 conditions |
| KCNJ5potassium inwardly rectifying channel subfamily J member 5 | Sometimes (5–29%) | In 1 condition |
| KIFBPkinesin family binding protein | Sometimes (5–29%) | In 1 condition |
| MAP3K7mitogen-activated protein kinase kinase kinase 7 | Sometimes (5–29%) | In 1 condition |
| PIGBphosphatidylinositol glycan anchor biosynthesis class B | Sometimes (5–29%) | In 1 condition |
| PPP1R15Bprotein phosphatase 1 regulatory subunit 15B | Sometimes (5–29%) | In 2 conditions |
| PSMD12proteasome 26S subunit, non-ATPase 12 | Sometimes (5–29%) | In 1 condition |
| PTHLHparathyroid hormone like hormone | Sometimes (5–29%) | In 1 condition |
| PUM1pumilio RNA binding family member 1 | Sometimes (5–29%) | In 1 condition |
| RHOAras homolog family member A | Sometimes (5–29%) | In 1 condition |
| RPS6KA3ribosomal protein S6 kinase A3 | Sometimes (5–29%) | In 2 conditions |
| SATB2SATB homeobox 2 | Sometimes (5–29%) | In 2 conditions |
| SCUBE3signal peptide, CUB domain and EGF like domain containing 3 | Sometimes (5–29%) | In 1 condition |
| SRCAPSnf2 related CREBBP activator protein | Sometimes (5–29%) | In 1 condition |
| TRIOtrio Rho guanine nucleotide exchange factor | Sometimes (5–29%) | In 1 condition |
| TRMT10AtRNA methyltransferase 10A | Sometimes (5–29%) | In 1 condition |
| WNT5AWnt family member 5A | Sometimes (5–29%) | In 1 condition |
| ZRSR2zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 | Sometimes (5–29%) | In 1 condition |
| PORCNporcupine O-acyltransferase | Rarely (1–4%) | In 2 conditions |
| CCBE1collagen and calcium binding EGF domains 1 | Not recorded | In 1 condition |
| HNRNPKheterogeneous nuclear ribonucleoprotein K | Not recorded | In 1 condition |
| SRD5A3steroid 5 alpha-reductase 3 | Not recorded | In 1 condition |
| TP63tumor protein p63 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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