Skip to content
Use your HSA or FSA funds
Sequence your genome (opens in a new tab)

Gene

ZRSR2

zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2

Summary

Cytogenetic location
Xp22.2
Coordinates
Chromosome X: 15,790,484–15,823,260 (GRCh38)
Exons
11 exons across 32.8 kb
Protein
482 amino acids
Also known as
U2AF1-RS2, URP, ZC3H22
Previous symbols
U2AF1L2
MANE Select transcript
ENST00000307771.8NM_005089.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads ZRSR2 yet. The test sequences your whole genome, so your data includes it all the same.

How ZRSR2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome X, with a bracket where ZRSR2 sits. ZRSR2 and 12 genes near it on chromosome X, from 15,306,872 to 16,306,871.Chromosome XXp22.2p22.33p22.32p22.31p22.2p22.13p22.12p22.11p21.3p21.2p21.1p11.4p11.3p11.23p11.22p11.21p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.31q21.32q21.33q22.1q22.2q22.3q23q24q25q26.1q26.2q26.3q27.1q27.2q27.3q2815.4 Mb15.6 Mb15.8 Mb16 Mb16.2 MbASB11: 15,281,486–15,315,658, reverse strandASB11PIGA: 15,319,452–15,335,556, reverse strandPIGAVEGFD: 15,345,594–15,384,510, reverse strandVEGFDPIR: 15,384,799–15,493,635, reverse strandPIRBMX: 15,464,246–15,556,529, forward strandBMXACE2: 15,494,290–15,607,236, reverse strandACE2: 15,561,047–15,675,608, reverse strandCLTRN: 15,627,084–15,675,377, reverse strandCLTRNCA5B: 15,688,830–15,788,411, forward strandCA5BZRSR2: 15,790,484–15,823,260, forward strandZRSR2AP1S2: 15,812,775–15,855,705, reverse strandAP1S2GRPR: 16,123,545–16,159,474, forward strandGRPRMAGEB17: 16,167,481–16,171,464, forward strandMAGEB17Diagram of ZRSR2: 11 exons on the forward strand of chromosome XExon 11: 1 known disease-causing siteExon 1: 15,790,484–15,790,536, 53 basesExon 2: 15,790,934–15,791,013, 80 basesExon 3: 15,799,872–15,799,953, 82 basesExon 4: 15,803,688–15,803,796, 109 basesExon 5: 15,804,111–15,804,197, 87 basesExon 6: 15,808,233–15,808,271, 39 basesExon 7: 15,809,200–15,809,318, 119 basesExon 8: 15,815,677–15,815,890, 214 basesExon 9: 15,818,587–15,818,642, 56 basesExon 10: 15,820,207–15,820,316, 110 basesExon 11: 15,822,731–15,823,260, 530 bases1510115′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.5 kb of the gene's 32.8 kb; 1,449 of those bases code for the protein.

How a genome test reads ZRSR2

1

position in ZRSR2 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 32.8 kb of ZRSR2, introns included, not only the 1.5 kb of exons.

Traits linked to ZRSR2

The Human Phenotype Ontology lists these as features of the rare conditions ZRSR2 can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). ZRSR2 gene: zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/zrsr2

Vancouver

Dante Labs. ZRSR2 gene: zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/zrsr2

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test