Trait
Intention tremor
A type of kinetic tremor that occurs during target directed movement is called intention tremor. That is, an oscillatory cerebellar ataxia that tends to be absent when the limbs are inactive and during the first part of voluntary movement but worsening as the movement continues and greater precision is required (e.g., in touching a target such as the patient's nose or a physician's finger).
Summary
- Body system
- Abnormality of the nervous system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Intention tremor, and the rest of your genome, with one test.
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Get my Genome Test115 genes linked to Intention tremor
Changes in these genes cause rare conditions in which Intention tremor is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ABCB7ATP binding cassette subfamily B member 7 | Always | In 1 condition |
| AMACRalpha-methylacyl-CoA racemase | Always | In 1 condition |
| ATP2B3ATPase plasma membrane Ca2+ transporting 3 | Always | In 2 conditions |
| CWF19L1CWF19 like cell cycle control factor 1 | Always | In 2 conditions |
| FMR1fragile X messenger ribonucleoprotein 1 | Always | In 2 conditions |
| INPP4Ainositol polyphosphate-4-phosphatase type I A | Always | In 1 condition |
| ITPR1inositol 1,4,5-trisphosphate receptor type 1 | Always | In 3 conditions |
| KDM6Blysine demethylase 6B | Always | In 1 condition |
| LAMB1laminin subunit beta 1 | Always | In 1 condition |
| LEMD2LEM domain nuclear envelope protein 2 | Always | In 1 condition |
| LMAN2Llectin, mannose binding 2 like | Always | In 1 condition |
| MALmal, T cell differentiation protein (MAL blood group) | Always | In 1 condition |
| PLP1proteolipid protein 1 | Always | In 1 condition |
| PNPLA6patatin like domain 6, lysophospholipase | Always | In 2 conditions |
| POLGDNA polymerase gamma, catalytic subunit | Always | In 1 condition |
| POU4F1POU class 4 homeobox 1 | Always | In 2 conditions |
| PPP2R5Cprotein phosphatase 2 regulatory subunit B'gamma | Always | In 1 condition |
| PSAPprosaposin | Always | In 3 conditions |
| RNU12RNA, U12 small nuclear | Always | In 2 conditions |
| SCP2sterol carrier protein 2 | Always | In 1 condition |
| SEMA6Bsemaphorin 6B | Always | In 1 condition |
| SMG9SMG9 nonsense mediated mRNA decay factor | Always | In 1 condition |
| SPTBN2spectrin beta, non-erythrocytic 2 | Always | In 3 conditions |
| TENM4teneurin transmembrane protein 4 | Always | In 1 condition |
| UCHL1ubiquitin C-terminal hydrolase L1 | Always | In 2 conditions |
| UNC13Aunc-13 homolog A | Always | In 1 condition |
| CACNA1Acalcium voltage-gated channel subunit alpha1 A | Very often (80–99%) | In 2 conditions |
| HYCC1hyccin PI4KA lipid kinase complex subunit 1 | Very often (80–99%) | In 1 condition |
| POLR3BRNA polymerase III subunit B | Very often (80–99%) | In 1 condition |
| ATCAYATCAY kinesin light chain interacting caytaxin | Often (30–79%) | In 2 conditions |
| ATMATM serine/threonine kinase | Often (30–79%) | In 1 condition |
| ATXN10ataxin 10 | Often (30–79%) | In 1 condition |
| CCDC88Ccoiled-coil and HOOK domain protein 88C | Often (30–79%) | In 2 conditions |
| CSTBcystatin B | Often (30–79%) | In 1 condition |
| EPRS1glutamyl-prolyl-tRNA synthetase 1 | Often (30–79%) | In 1 condition |
| ERCC6ERCC excision repair 6, chromatin remodeling factor | Often (30–79%) | In 1 condition |
| ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit | Often (30–79%) | In 1 condition |
| FARS2phenylalanyl-tRNA synthetase 2, mitochondrial | Often (30–79%) | In 1 condition |
| FBXO7F-box protein 7 | Often (30–79%) | In 1 condition |
| FXNfrataxin | Often (30–79%) | In 1 condition |
Show 75 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| GJB1gap junction protein beta 1 | Often (30–79%) | In 1 condition |
| HMBShydroxymethylbilane synthase | Often (30–79%) | In 1 condition |
| HSD17B4hydroxysteroid 17-beta dehydrogenase 4 | Often (30–79%) | In 1 condition |
| KCNK4potassium two pore domain channel subfamily K member 4 | Often (30–79%) | In 1 condition |
| KCNN2potassium calcium-activated channel subfamily N member 2 | Often (30–79%) | In 1 condition |
| KNSTRNkinetochore localized astrin (SPAG5) binding protein | Often (30–79%) | In 1 condition |
| MRE11MRE11 double strand break repair nuclease | Often (30–79%) | In 1 condition |
| PI4KAphosphatidylinositol 4-kinase alpha | Often (30–79%) | In 1 condition |
| PIK3CDphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | Often (30–79%) | In 1 condition |
| PMM2phosphomannomutase 2 | Often (30–79%) | In 1 condition |
| POLR3ARNA polymerase III subunit A | Often (30–79%) | In 2 conditions |
| PRICKLE1prickle planar cell polarity protein 1 | Often (30–79%) | In 1 condition |
| QRICH1glutamine rich 1 | Often (30–79%) | In 1 condition |
| RAB3ARAB3A, member RAS oncogene family | Often (30–79%) | In 1 condition |
| RARS1arginyl-tRNA synthetase 1 | Often (30–79%) | In 2 conditions |
| RBSNrabenosyn, RAB effector | Often (30–79%) | In 1 condition |
| RFC1replication factor C subunit 1 | Often (30–79%) | In 1 condition |
| SCARB2scavenger receptor class B member 2 | Often (30–79%) | In 2 conditions |
| SCYL1SCY1 like pseudokinase 1 | Often (30–79%) | In 1 condition |
| SNCAsynuclein alpha | Often (30–79%) | In 1 condition |
| TECRtrans-2,3-enoyl-CoA reductase | Often (30–79%) | In 1 condition |
| TGM6transglutaminase 6 | Often (30–79%) | In 2 conditions |
| TMCO1transmembrane and coiled-coil domains 1 | Often (30–79%) | In 1 condition |
| TMEM106Btransmembrane protein 106B | Often (30–79%) | In 1 condition |
| TMEM240transmembrane protein 240 | Often (30–79%) | In 1 condition |
| TPRtranslocated promoter region, nuclear basket protein | Often (30–79%) | In 1 condition |
| TSPOAP1TSPO associated protein 1 | Often (30–79%) | In 1 condition |
| WDR81WD repeat domain 81 | Often (30–79%) | In 1 condition |
| AARS1alanyl-tRNA synthetase 1 | Sometimes (5–29%) | In 1 condition |
| ABHD12abhydrolase domain containing 12, lysophospholipase | Sometimes (5–29%) | In 1 condition |
| ADPRSADP-ribosylserine hydrolase | Sometimes (5–29%) | In 1 condition |
| ANO10anoctamin 10 | Sometimes (5–29%) | In 2 conditions |
| ARSAarylsulfatase A | Sometimes (5–29%) | In 2 conditions |
| CACNA1Ccalcium voltage-gated channel subunit alpha1 C | Sometimes (5–29%) | In 1 condition |
| CARS1cysteinyl-tRNA synthetase 1 | Sometimes (5–29%) | In 1 condition |
| CTDP1CTD phosphatase 1 | Sometimes (5–29%) | In 1 condition |
| DBR1debranching RNA lariats 1 | Sometimes (5–29%) | In 1 condition |
| EEFSECeukaryotic elongation factor, selenocysteine-tRNA specific | Sometimes (5–29%) | In 1 condition |
| ELOVL4ELOVL fatty acid elongase 4 | Sometimes (5–29%) | In 1 condition |
| ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit | Sometimes (5–29%) | In 1 condition |
| ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit | Sometimes (5–29%) | In 1 condition |
| GTF2E2general transcription factor IIE subunit 2 | Sometimes (5–29%) | In 1 condition |
| GTF2H5general transcription factor IIH subunit 5 | Sometimes (5–29%) | In 1 condition |
| KIF1Ckinesin family member 1C | Sometimes (5–29%) | In 1 condition |
| LMNB1lamin B1 | Sometimes (5–29%) | In 1 condition |
| MPLKIPM-phase specific PLK1 interacting protein | Sometimes (5–29%) | In 1 condition |
| NKX2-1NK2 homeobox 1 | Sometimes (5–29%) | In 1 condition |
| NONOnon-POU domain containing octamer binding | Sometimes (5–29%) | In 1 condition |
| OPHN1oligophrenin 1 | Sometimes (5–29%) | In 1 condition |
| PEX10peroxisomal biogenesis factor 10 | Sometimes (5–29%) | In 1 condition |
| PPP2R2Bprotein phosphatase 2 regulatory subunit Bbeta | Sometimes (5–29%) | In 1 condition |
| RFC4replication factor C subunit 4 | Sometimes (5–29%) | In 1 condition |
| RNF113Aring finger protein 113A | Sometimes (5–29%) | In 1 condition |
| SACSsacsin molecular chaperone | Sometimes (5–29%) | In 1 condition |
| SLC25A46solute carrier family 25 member 46 | Sometimes (5–29%) | In 1 condition |
| TARS1threonyl-tRNA synthetase 1 | Sometimes (5–29%) | In 1 condition |
| TMEM63Atransmembrane protein 63A | Sometimes (5–29%) | In 1 condition |
| TPK1thiamin pyrophosphokinase 1 | Sometimes (5–29%) | In 1 condition |
| TTRtransthyretin | Sometimes (5–29%) | In 1 condition |
| UFC1ubiquitin-fold modifier conjugating enzyme 1 | Sometimes (5–29%) | In 1 condition |
| CAMTA1calmodulin binding transcription activator 1 | Rarely (1–4%) | In 1 condition |
| NOP56NOP56 ribonucleoprotein | Rarely (1–4%) | In 1 condition |
| SPTBN1spectrin beta, non-erythrocytic 1 | Rarely (1–4%) | In 1 condition |
| GJC2gap junction protein gamma 2 | Not recorded | In 2 conditions |
| GSSglutathione synthetase | Not recorded | In 1 condition |
| ITM2Bintegral membrane protein 2B | Not recorded | In 1 condition |
| KCNJ10potassium inwardly rectifying channel subfamily J member 10 | Not recorded | In 1 condition |
| NFASCneurofascin | Not recorded | In 1 condition |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Not recorded | In 1 condition |
| PLA2G6phospholipase A2 group VI | Not recorded | In 1 condition |
| PTENphosphatase and tensin homolog | Not recorded | In 1 condition |
| TBPTATA-box binding protein | Not recorded | In 1 condition |
| TMEM70transmembrane protein 70 | Not recorded | In 1 condition |
| VLDLRvery low density lipoprotein receptor | Not recorded | In 1 condition |
| VWA3Bvon Willebrand factor A domain containing 3B | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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