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Gene

ADPRS

ADP-ribosylserine hydrolase

Summary

Cytogenetic location
1p34.3
Coordinates
Chromosome 1: 36,088,892–36,093,932 (GRCh38)
Exons
6 exons across 5 kb
Protein
363 amino acids
Also known as
ARH3, FLJ20446
Previous symbols
ADPRHL2
MANE Select transcript
ENST00000373178.5NM_017825.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads ADPRS yet. The test sequences your whole genome, so your data includes it all the same.

How ADPRS is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
Chromosome 1, with a bracket where ADPRS sits. ADPRS and 19 genes near it on chromosome 1, from 35,591,412 to 36,591,411.Chromosome 11p34.3p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q4435.6 Mb35.8 Mb36 Mb36.2 Mb36.4 MbTFAP2E: 35,573,309–35,595,590, forward strandTFAP2EPSMB2: 35,599,541–35,641,568, reverse strandPSMB2C1orf216: 35,713,875–35,718,894, reverse strandC1orf216CLSPN: 35,720,202–35,770,002, reverse strandCLSPNAGO4: 35,807,976–35,857,890, forward strandAGO4AGO1: 35,869,808–35,930,532, forward strandAGO1AGO3: 35,930,696–36,072,500, forward strandAGO3TEKT2: 36,084,080–36,088,278, forward strandTEKT2ADPRS: 36,088,892–36,093,932, forward strandADPRSCOL8A2: 36,095,239–36,125,234, reverse strandCOL8A2TRAPPC3: 36,136,570–36,156,053, reverse strandTRAPPC3MAP7D1: 36,155,541–36,180,849, forward strandMAP7D1THRAP3: 36,224,392–36,305,376, forward strandTHRAP3MNMIP1: 36,306,314–36,329,340, forward strandMNMIP1EVA1B: 36,322,030–36,324,154, reverse strandEVA1BSTK40: 36,339,620–36,385,932, reverse strandSTK40LSM10: 36,388,814–36,397,945, reverse strandLSM10OSCP1: 36,415,273–36,450,491, reverse strandOSCP1MRPS15: 36,455,718–36,464,418, reverse strandMRPS15CSF3R: 36,465,669–36,483,322, reverse strandCSF3RDiagram of ADPRS: 6 exons on the forward strand of chromosome 1Exon 1: 2 known disease-causing sitesExon 2: 2 known disease-causing sitesExon 3: 4 known disease-causing sitesExon 4: 6 known disease-causing sitesExon 5: 2 known disease-causing sitesExon 6: 1 known disease-causing siteExon 1: 36,088,892–36,089,115, 224 basesExon 2: 36,091,244–36,091,340, 97 basesExon 3: 36,091,618–36,091,825, 208 basesExon 4: 36,091,910–36,092,094, 185 basesExon 5: 36,092,422–36,092,522, 101 basesExon 6: 36,093,097–36,093,932, 836 bases1234565′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.7 kb of the gene's 5 kb; 1,092 of those bases code for the protein.

How a genome test reads ADPRS

17

positions in ADPRS where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 5 kb of ADPRS, introns included, not only the 1.7 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). ADPRS gene: ADP-ribosylserine hydrolase. Retrieved 16 October 2026, from https://dantelabs.com/genes/adprs

Vancouver

Dante Labs. ADPRS gene: ADP-ribosylserine hydrolase [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/adprs

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