Skip to content
Use your HSA or FSA funds

Gene

ABHD12

abhydrolase domain containing 12, lysophospholipase

Summary

Cytogenetic location
20p11.21
Coordinates
Chromosome 20: 25,300,214–25,390,835 (GRCh38)
Exons
13 exons across 90.6 kb
Protein
398 amino acids
Also known as
DKFZP434P106, dJ965G21.2, BEM46L2, ABHD12A
Previous symbols
C20orf22
MANE Select transcript
ENST00000339157.10NM_001042472.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads ABHD12 yet. The test sequences your whole genome, so your data includes it all the same.

How ABHD12 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 20, with a bracket where ABHD12 sits. ABHD12 and 10 genes near it on chromosome 20, from 24,845,525 to 25,845,524.Chromosome 2020p11.21p13p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q12q13.11q13.12q13.13q13.2q13.31q13.32q13.3325 Mb25.2 Mb25.4 Mb25.6 Mb25.8 MbCST7: 24,949,257–24,961,392, forward strandCST7APMAP: 24,962,924–24,992,784, reverse strandAPMAPACSS1: 25,003,364–25,058,980, reverse strandACSS1VSX1: 25,069,941–25,082,141, reverse strandVSX1ENTPD6: 25,195,693–25,228,075, forward strandENTPD6PYGB: 25,248,030–25,298,014, forward strandPYGBABHD12: 25,300,214–25,390,835, reverse strandABHD12GINS1: 25,391,008–25,452,700, forward strandGINS1NINL: 25,451,594–25,585,586, reverse strandNINLNANP: 25,612,935–25,624,020, reverse strandNANPZNF337: 25,673,195–25,696,884, reverse strandZNF337Diagram of ABHD12: 13 exons on the reverse strand of chromosome 20Exon 12: 2 known disease-causing sitesExon 11: 1 known disease-causing siteExon 10: 1 known disease-causing siteExon 7: 1 known disease-causing siteExon 6: 1 known disease-causing siteExon 4: 1 known disease-causing siteExon 2: 1 known disease-causing siteExon 1: 2 known disease-causing sitesExon 13: 25,300,214–25,300,884, 671 basesExon 12: 25,302,219–25,302,346, 128 basesExon 11: 25,303,550–25,303,628, 79 basesExon 10: 25,306,833–25,306,915, 83 basesExon 9: 25,307,966–25,308,045, 80 basesExon 8: 25,308,457–25,308,494, 38 basesExon 7: 25,309,446–25,309,575, 130 basesExon 6: 25,314,925–25,314,970, 46 basesExon 5: 25,317,048–25,317,078, 31 basesExon 4: 25,320,199–25,320,318, 120 basesExon 3: 25,323,325–25,323,430, 106 basesExon 2: 25,339,227–25,339,351, 125 basesExon 1: 25,390,513–25,390,835, 323 bases1310515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2 kb of the gene's 90.6 kb; 1,197 of those bases code for the protein.

How a genome test reads ABHD12

11

positions in ABHD12 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 90.6 kb of ABHD12, introns included, not only the 2 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). ABHD12 gene: abhydrolase domain containing 12, lysophospholipase. Retrieved 17 October 2026, from https://dantelabs.com/genes/abhd12

Vancouver

Dante Labs. ABHD12 gene: abhydrolase domain containing 12, lysophospholipase [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/abhd12

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test