Gene
KNSTRN
kinetochore localized astrin (SPAG5) binding protein
- HGNC 30767↗(opens in a new tab)
- Ensembl gene ENSG00000128944↗(opens in a new tab)
- NCBI Gene 90417↗(opens in a new tab)
Summary
- Cytogenetic location
- 15q15.1
- Coordinates
- Chromosome 15: 40,382,721–40,394,288 (GRCh38)
- Exons
- 9 exons across 11.6 kb
- Protein
- 316 amino acids
- Also known as
- FLJ14502, SKAP, kinastrin, TRAF4AF1
- Previous symbols
- C15orf23
- MANE Select transcript
- ENST00000249776.13NM_033286.4
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How KNSTRN is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 1.8 kb of the gene's 11.6 kb; 951 of those bases code for the protein.
Traits linked to KNSTRN
The Human Phenotype Ontology lists these as features of the rare conditions KNSTRN can cause. Each trait's page lists the other genes linked to it.
Abnormality of the immune system
- Combined immunodeficiency
- Decreased specific antibody response to vaccination
- Psoriasiform dermatitis
- Recurrent aspiration pneumonia
- Recurrent bacterial infections
- Recurrent ear infections
- Recurrent fungal infections
- Recurrent viral infections
Show 1 more trait
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). KNSTRN gene: kinetochore localized astrin (SPAG5) binding protein. Retrieved 17 October 2026, from https://dantelabs.com/genes/knstrn
Dante Labs. KNSTRN gene: kinetochore localized astrin (SPAG5) binding protein [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/knstrn
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