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Gene

PPP2R5C

protein phosphatase 2 regulatory subunit B'gamma

Summary

Cytogenetic location
14q32.31
Coordinates
Chromosome 14: 101,761,709–101,927,977 (GRCh38)
Exons
16 exons across 166.3 kb
Protein
579 amino acids
Also known as
B56G, PR61G, B56gamma
MANE Select transcript
ENST00000694906.1NM_001352913.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads PPP2R5C yet. The test sequences your whole genome, so your data includes it all the same.

How PPP2R5C is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 14, with a bracket where PPP2R5C sits. PPP2R5C and 7 genes near it on chromosome 14, from 101,344,843 to 102,344,842.Chromosome 1414q32.31p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.11q32.12q32.13q32.2q32.31q32.32q32.33101.4 Mb101.6 Mb101.8 Mb102 Mb102.2 MbDIO3: 101,560,139–101,563,452, forward strandDIO3PPP2R5C: 101,761,709–101,927,977, forward strandPPP2R5CDYNC1H1: 101,964,519–102,056,443, forward strandDYNC1H1HSP90AA1: 102,080,738–102,139,773, reverse strandHSP90AA1WDR20: 102,139,503–102,224,847, forward strandWDR20MOK: 102,224,500–102,305,193, reverse strandMOKZNF839: 102,317,377–102,344,638, forward strandZNF839CINP: 102,341,102–102,362,916, reverse strandCINPDiagram of PPP2R5C: 16 exons on the forward strand of chromosome 14Exon 4: 1 known disease-causing siteExon 5: 1 known disease-causing siteExon 12: 1 known disease-causing siteExon 1: 101,761,709–101,761,920, 212 basesExon 2: 101,762,905–101,762,970, 66 basesExon 3: 101,786,018–101,786,183, 166 basesExon 4: 101,856,686–101,856,885, 200 basesExon 5: 101,882,161–101,882,271, 111 basesExon 6: 101,883,257–101,883,349, 93 basesExon 7: 101,883,432–101,883,562, 131 basesExon 8: 101,890,237–101,890,296, 60 basesExon 9: 101,893,000–101,893,108, 109 basesExon 10: 101,894,507–101,894,560, 54 basesExon 11: 101,901,719–101,901,889, 171 basesExon 12: 101,906,402–101,906,529, 128 basesExon 13: 101,909,589–101,909,690, 102 basesExon 14: 101,912,401–101,912,473, 73 basesExon 15: 101,917,831–101,917,947, 117 basesExon 16: 101,925,141–101,927,977, 2,837 bases151015165′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.6 kb of the gene's 166.3 kb; 1,740 of those bases code for the protein.

How a genome test reads PPP2R5C

3

positions in PPP2R5C where ClinVar classes a change as pathogenic or likely pathogenic

1 of them (33%) falls in a region short reads find hard.

  • Low mappability (1 site)Regions where 100 bp or 250 bp reads cannot be placed uniquely.

A whole genome covers all 166.3 kb of PPP2R5C, introns included, not only the 4.6 kb of exons.

Traits linked to PPP2R5C

The Human Phenotype Ontology lists these as features of the rare conditions PPP2R5C can cause. Each trait's page lists the other genes linked to it.

Abnormality of the nervous system

Show 38 more traits

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). PPP2R5C gene: protein phosphatase 2 regulatory subunit B'gamma. Retrieved 17 October 2026, from https://dantelabs.com/genes/ppp2r5c

Vancouver

Dante Labs. PPP2R5C gene: protein phosphatase 2 regulatory subunit B'gamma [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/ppp2r5c

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