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Gene

SLC25A46

solute carrier family 25 member 46

Summary

Cytogenetic location
5q22.1
Coordinates
Chromosome 5: 110,739,007–110,765,157 (GRCh38)
Exons
8 exons across 26.2 kb
Protein
418 amino acids
MANE Select transcript
ENST00000355943.8NM_138773.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SLC25A46 yet. The test sequences your whole genome, so your data includes it all the same.

How SLC25A46 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 5, with a bracket where SLC25A46 sits. SLC25A46 and 4 genes near it on chromosome 5, from 110,252,082 to 111,252,081.Chromosome 55q22.1p15.33p15.32p15.31p15.2p15.1p14.3p14.2p14.1p13.3p13.2p13.1p12p11q11.1q11.2q12.1q12.2q12.3q13.1q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q31.1q31.2q31.3q32q33.1q33.2q33.3q34q35.1q35.2q35.3110.4 Mb110.6 Mb110.8 Mb111 Mb111.2 MbTMEM232: 110,289,233–110,738,960, reverse strandTMEM232SLC25A46: 110,739,007–110,765,157, forward strandSLC25A46TSLP: 111,070,062–111,078,026, forward strandTSLPWDR36: 111,092,303–111,130,502, forward strandWDR36CAMK4: 111,223,653–111,494,886, forward strandCAMK4Diagram of SLC25A46: 8 exons on the forward strand of chromosome 5Exon 1: 5 known disease-causing sitesExon 2: 1 known disease-causing siteExon 5: 1 known disease-causing siteExon 6: 2 known disease-causing sitesExon 7: 1 known disease-causing siteExon 8: 6 known disease-causing sitesExon 1: 110,739,007–110,739,402, 396 basesExon 2: 110,742,047–110,742,089, 43 basesExon 3: 110,743,730–110,743,787, 58 basesExon 4: 110,746,269–110,746,346, 78 basesExon 5: 110,748,163–110,748,263, 101 basesExon 6: 110,755,465–110,755,521, 57 basesExon 7: 110,756,702–110,756,759, 58 basesExon 8: 110,761,204–110,765,157, 3,954 bases123456785′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.7 kb of the gene's 26.2 kb; 1,257 of those bases code for the protein.

How a genome test reads SLC25A46

21

positions in SLC25A46 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 26.2 kb of SLC25A46, introns included, not only the 4.7 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). SLC25A46 gene: solute carrier family 25 member 46. Retrieved 17 October 2026, from https://dantelabs.com/genes/slc25a46

Vancouver

Dante Labs. SLC25A46 gene: solute carrier family 25 member 46 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/slc25a46

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