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Gene

TPR

translocated promoter region, nuclear basket protein

Summary

Cytogenetic location
1q31.1
Coordinates
Chromosome 1: 186,311,652–186,375,253 (GRCh38)
Exons
51 exons across 63.6 kb
Protein
2,363 amino acids
MANE Select transcript
ENST00000367478.9NM_003292.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TPR yet. The test sequences your whole genome, so your data includes it all the same.

How TPR is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 1, with a bracket where TPR sits. TPR and 6 genes near it on chromosome 1, from 185,843,453 to 186,843,452.Chromosome 11q31.1p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q44186 Mb186.2 Mb186.4 Mb186.6 Mb186.8 MbHMCN1: 185,734,371–186,190,949, forward strandHMCN1PRG4: 186,296,222–186,314,567, forward strandPRG4TPR: 186,311,652–186,375,253, reverse strandTPRODR4: 186,375,401–186,421,408, forward strandODR4PDC: 186,443,566–186,461,114, reverse strandPDCPTGS2: 186,671,791–186,680,922, reverse strandPTGS2PLA2G4A: 186,828,949–186,989,902, forward strandPLA2G4ADiagram of TPR: 51 exons on the reverse strand of chromosome 1Exon 51: 186,311,652–186,314,026, 2,375 basesExon 50: 186,314,629–186,314,724, 96 basesExon 49: 186,317,482–186,317,600, 119 basesExon 48: 186,318,447–186,318,603, 157 basesExon 47: 186,318,733–186,318,828, 96 basesExon 46: 186,320,312–186,320,418, 107 basesExon 45: 186,322,318–186,322,412, 95 basesExon 44: 186,322,518–186,322,586, 69 basesExon 43: 186,323,686–186,323,870, 185 basesExon 42: 186,325,764–186,325,854, 91 basesExon 41: 186,326,104–186,326,235, 132 basesExon 40: 186,327,460–186,327,660, 201 basesExon 39: 186,331,498–186,331,581, 84 basesExon 38: 186,332,195–186,332,343, 149 basesExon 37: 186,333,122–186,333,394, 273 basesExon 36: 186,334,325–186,334,533, 209 basesExon 35: 186,335,068–186,335,129, 62 basesExon 34: 186,335,338–186,335,543, 206 basesExon 33: 186,336,496–186,336,694, 199 basesExon 32: 186,337,013–186,337,156, 144 basesExon 31: 186,338,033–186,338,243, 211 basesExon 30: 186,339,642–186,339,772, 131 basesExon 29: 186,341,028–186,341,159, 132 basesExon 28: 186,341,252–186,341,389, 138 basesExon 27: 186,343,326–186,343,473, 148 basesExon 26: 186,343,906–186,344,090, 185 basesExon 25: 186,344,375–186,344,578, 204 basesExon 24: 186,345,580–186,345,696, 117 basesExon 23: 186,346,135–186,346,287, 153 basesExon 22: 186,347,292–186,347,458, 167 basesExon 21: 186,350,223–186,350,388, 166 basesExon 20: 186,351,330–186,351,470, 141 basesExon 19: 186,351,976–186,352,110, 135 basesExon 18: 186,353,688–186,353,850, 163 basesExon 17: 186,355,410–186,355,558, 149 basesExon 16: 186,355,635–186,355,768, 134 basesExon 15: 186,356,286–186,356,449, 164 basesExon 14: 186,357,397–186,357,623, 227 basesExon 13: 186,358,543–186,358,650, 108 basesExon 12: 186,359,799–186,359,996, 198 basesExon 11: 186,360,273–186,360,364, 92 basesExon 10: 186,360,765–186,360,905, 141 basesExon 9: 186,361,622–186,361,709, 88 basesExon 8: 186,361,789–186,361,869, 81 basesExon 7: 186,362,288–186,362,380, 93 basesExon 6: 186,362,837–186,363,001, 165 basesExon 5: 186,363,342–186,363,445, 104 basesExon 4: 186,367,886–186,367,982, 97 basesExon 3: 186,370,970–186,371,043, 74 basesExon 2: 186,373,359–186,373,463, 105 basesExon 1: 186,374,878–186,375,253, 376 bases51504540353025201510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 9.6 kb of the gene's 63.6 kb; 7,092 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). TPR gene: translocated promoter region, nuclear basket protein. Retrieved 16 October 2026, from https://dantelabs.com/genes/tpr

Vancouver

Dante Labs. TPR gene: translocated promoter region, nuclear basket protein [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/tpr

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