유전자
SALL4
spalt like transcription factor 4
요약
- 세포유전학적 위치
- 20q13.2
- 좌표
- 염색체 20: 51,782,331–51,802,521 (GRCh38)
- 엑손
- 엑손 4개, 20.2 kb에 걸쳐
- 단백질
- 아미노산 1,053개
- 다른 이름
- dJ1112F19.1, ZNF797
- MANE Select 전사체
- ENST00000217086.9NM_020436.5
- 유전자좌 유형
- gene with protein product
- Very high
- Confident
- Low
- Very low
이 유전자와 관련된 큐레이션 보고서
No Genome Test report reads SALL4 yet. The test sequences your whole genome, so your data includes it all the same.
SALL4의 구조
- 코딩 서열
- 비번역 영역
- 인트론
- 전사 방향
- 알려진 질병 유발 부위
- 짧은 리드가 판독하기 어려운 구간
v1.5 릴리스 기준, 이 유전자의 MANE Select 전사체 엑손이며 NCBI와 EMBL-EBI 자료를 바탕으로 하고 GRCh38 참조 게놈에 기반합니다.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
유전자 전체 20.2 kb 중 엑손이 5.2 kb를 차지하며, 이 중 3,162개의 염기가 단백질을 암호화합니다.
전장 유전체 검사가 SALL4 유전자를 읽는 방법
33
SALL4 내 위치 중 ClinVar가 병원성 또는 가능성 높은 병원성으로 분류하는 위치
이 중 어느 곳도 짧은 리드가 판독하기 어려운 구간에 있지 않습니다.
전장 유전체 검사는 인트론을 포함해 SALL4의 전체 20.2kb를 모두 포함하며, 엑손 5.2kb만 보는 것이 아닙니다.
Traits linked to SALL4
The Human Phenotype Ontology lists these as features of the rare conditions SALL4 can cause. Each trait's page lists the other genes linked to it.
Abnormality of limbs
- Short thighbone
- Underdeveloped inner large forearm bone
- Underdeveloped outer large forearm bone
- Abnormal morphology of the radius
- Abnormality of the thumb
- Aplasia/Hypoplasia of the radius
- Short outermost bone of the thumb
- Short thumb
Show 33 more traits
- Small thenar eminence
- Absent thumb
- Broad bone of big toe
- Extra thumb
- Finger-like thumb
- Fused forearm bones
- Fused wrist bones
- Fusion of wrist bones
- Gap between 1st and 2nd toes
- Radial ray deficiency
- Short big toe
- Upper limb undergrowth
- Absent/small thumb
- Club feet
- Finger syndactyly
- Fused toes
- Missing outer large bone of forearm
- Preaxial polydactyly
- Short fingers or toes
- Short humerus
- Small pec muscle
- Talipes
- Absent long bone of hand
- Dropped arches
- Hypoplasia of deltoid muscle
- Limited elbow movement
- Limited movement of hinge joints
- Limited wrist movement
- Radial deviation of the hand
- Shortened 1st long bone of hand
- Small carpal bones
- Underdevelopment of upper limb muscles
- Webbed fingers or toes
Abnormality of the eye
- Abnormality of eye movement
- Abnormally small eyeball
- Cross-eyed
- Duane anomaly
- Oculomotor apraxia
- Oculomotor nerve palsy
- Deeply set eye
- Impaired ocular abduction
Show 24 more traits
- Impaired ocular adduction
- Optic disc coloboma
- Optic disc hypoplasia
- Paroxysmal tonic upgaze
- Visual impairment
- Abnormality of the pupil
- Absent iris
- Birth defect that causes a hole in the innermost layer at the back of the eye
- Cat eye
- Central heterochromia
- Clouding of the lens of the eye
- Compensatory head posture
- Cornea of eye less than 10mm in diameter
- Drooping upper eyelid
- Gustatory lacrimation
- Hypoplastic iris stroma
- Involuntary, rapid, rhythmic eye movements
- Lazy eye
- Marcus Gunn jaw winking synkinesis
- Notched pupil
- Wide-set eyes
- Hole in the back of the eye
- Impaired convergence
- Paralysis or weakness of muscles within or surrounding outer part of eye
Abnormality of head or neck
- Short opening between the eyelids
- Low hairline at back of neck
- Narrow opening between the eyelids
- Nasal tip, upturned
- Abnormally small head
- Asymmetry of the posterior head
- Cleft palate
- Drooping lower lip
Show 14 more traits
- Eye folds
- Eyelid spasm
- Facial asymmetry
- Frontal bossing
- Little lower jaw
- Short neck
- Skin tag in front of the ear
- Webbed neck
- Wide nasal bridge
- Abnormal nasopharynx morphology
- Bell's palsy
- Blockage of the rear opening of the nasal cavity
- Narrowing of the rear opening of the nasal cavity
- Palpebral fissure narrowing on adduction
Abnormality of the genitourinary system
- Abnormal rotation of the kidneys
- Crossed fused renal ectopia
- Horseshoe kidney
- Absent/small kidney
- Bladder diverticulum
- Abnormal kidney location
- Vesicoureteral reflux
- Absent kidney
Show 2 more traits
외부 링크
단백질
이 정보의 출처
- HGNC: 유전자의 기호, 명칭, 다른 기호 및 위치입니다.
- NCBI와 EMBL-EBI의 MANE Select v1.5: 전사체, 엑손 및 코딩 서열입니다.
- ClinVar와 GIAB 층화 자료: 알려진 질병 유발 부위와 짧은 리드(short read)로 분석하기 어려운 영역입니다.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- 데이터 릴리스 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). SALL4 gene: spalt like transcription factor 4. Retrieved 2026년 10월 17일, from https://dantelabs.com/ko/genes/sall4
Dante Labs. SALL4 gene: spalt like transcription factor 4 [Internet]. [cited 2026년 10월 17일]. Available from: https://dantelabs.com/ko/genes/sall4
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