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Gene

EMC3

ER membrane protein complex subunit 3

Summary

Cytogenetic location
3p25.3
Coordinates
Chromosome 3: 9,962,682–9,986,841 (GRCh38)
Exons
8 exons across 24.2 kb
Protein
261 amino acids
Previous symbols
TMEM111
MANE Select transcript
ENST00000245046.7NM_001394674.1
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads EMC3 yet. The test sequences your whole genome, so your data includes it all the same.

How EMC3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 3, with a bracket where EMC3 sits. EMC3 and 30 genes near it on chromosome 3, from 9,474,762 to 10,474,761.Chromosome 33p25.3p26.3p26.2p26.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13.11q13.12q13.13q13.2q13.31q13.32q13.33q21.1q21.2q21.3q22.1q22.2q22.3q23q24q25.1q25.2q25.31q25.32q25.33q26.1q26.2q26.31q26.32q26.33q27.1q27.2q27.3q28q299.6 Mb9.8 Mb10 Mb10.2 Mb10.4 MbSETD5: 9,397,609–9,479,240, forward strandSETD5LHFPL4: 9,498,361–9,553,862, reverse strandLHFPL4MTMR14: 9,649,307–9,702,394, forward strandMTMR14CPNE9: 9,703,691–9,729,908, forward strandCPNE9BRPF1: 9,731,726–9,748,019, forward strandBRPF1OGG1: 9,749,938–9,791,067, forward strandOGG1CAMK1: 9,757,341–9,770,606, reverse strandTADA3: 9,779,964–9,793,011, reverse strandARPC4: 9,792,484–9,807,704, forward strandARPC4ARPC4-TTLL3: 9,793,082–9,835,401, forward strandARPC4-TTLL3TTLL3: 9,808,086–9,856,087, forward strandTTLL3RPUSD3: 9,831,633–9,844,602, reverse strandRPUSD3CIDEC: 9,864,169–9,891,008, reverse strandCIDECJAGN1: 9,890,569–9,894,349, forward strandJAGN1IL17RE: 9,902,612–9,916,402, forward strandIL17RC: 9,917,040–9,933,630, forward strandIL17RC: 9,917,116–9,945,385, forward strandCRELD1: 9,933,791–9,945,413, forward strandCRELD1PRRT3: 9,939,450–9,952,442, reverse strandPRRT3EMC3: 9,962,682–9,986,841, reverse strandEMC3FANCD2: 10,026,370–10,101,937, forward strandFANCD2FANCD2OS: 10,081,317–10,108,290, reverse strandFANCD2OSBRK1: 10,115,590–10,135,082, forward strandBRK1VHL: 10,141,764–10,153,676, forward strandVHLIRAK2: 10,164,862–10,243,756, forward strandIRAK2TATDN2: 10,248,023–10,281,218, forward strandTATDN2: 10,249,042–10,249,366, forward strand: 10,249,372–10,285,796, forward strandGHRL: 10,285,666–10,292,959, reverse strandGHRLSEC13: 10,293,131–10,321,207, reverse strandSEC13ATP2B2: 10,324,023–10,708,060, reverse strandATP2B2Diagram of EMC3: 8 exons on the reverse strand of chromosome 3Exon 8: 9,962,682–9,964,197, 1,516 basesExon 7: 9,969,719–9,969,801, 83 basesExon 6: 9,970,582–9,970,661, 80 basesExon 5: 9,973,628–9,973,709, 82 basesExon 4: 9,974,384–9,974,488, 105 basesExon 3: 9,976,957–9,977,050, 94 basesExon 2: 9,977,389–9,977,446, 58 basesExon 1: 9,986,507–9,986,841, 335 bases876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.4 kb of the gene's 24.2 kb; 786 of those bases code for the protein.

Sequencing EMC3

5Easy

How hard EMC3 is to sequence with short reads, out of 100

Almost all of EMC3's exons sit where short reads map cleanly.

What adds to it: the share of EMC3's exons in each kind of hard region

  • Mappability0%
  • Homology14%
  • Repeats4.9%
  • GC content0%
  • Reference coverage0%

A Dante Labs score from our own research, built on NIST's Genome in a Bottle maps of hard-to-sequence regions.How it's scored

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.

Cite this page

APA

Dante Labs. (n.d.). EMC3 gene: ER membrane protein complex subunit 3. Retrieved 18 October 2026, from https://dantelabs.com/genes/emc3

Vancouver

Dante Labs. EMC3 gene: ER membrane protein complex subunit 3 [Internet]. [cited 18 October 2026]. Available from: https://dantelabs.com/genes/emc3

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