Trait
High blood sodium levels
Clinical name: Hypernatremia
The concentration of sodium in the blood circulation is above the upper limit of normal.
Summary
- Also called
- Elevated sodium(1+) concentration, Elevated sodium(1+) level, Elevated sodium(1+) level in blood, Increased sodium(1+) concentration, Increased sodium(1+) level, Increased sodium(1+) level in blood
- Body system
- Laboratory abnormality
Reference genomeGRCh38hg38
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Get my Genome Test11 genes linked to High blood sodium levels
Changes in these genes cause rare conditions in which High blood sodium levels is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| AQP2aquaporin 2 | Always | In 2 conditions |
| ARNT2aryl hydrocarbon receptor nuclear translocator 2 | Always | In 1 condition |
| DSG1desmoglein 1 | Always | In 1 condition |
| AVPR2arginine vasopressin receptor 2 | Very often (80–99%) | In 2 conditions |
| GCSHglycine cleavage system protein H | Often (30–79%) | In 1 condition |
| SLC5A1solute carrier family 5 member 1 | Often (30–79%) | In 1 condition |
| SPINK5serine peptidase inhibitor Kazal type 5 | Often (30–79%) | In 1 condition |
| CA5Acarbonic anhydrase 5A | Sometimes (5–29%) | In 1 condition |
| CRELD1CRELD disulfide isomerase 1 | Sometimes (5–29%) | In 1 condition |
| SYKspleen associated tyrosine kinase | Sometimes (5–29%) | In 1 condition |
| FGFR1fibroblast growth factor receptor 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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