Trait
Hypothermia
Reduced body temperature due to failed thermoregulation.
Summary
- Also called
- Abnormally low body temperature
- Body system
- Laboratory abnormality
Reference genomeGRCh38hg38
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Get my Genome Test59 genes linked to Hypothermia
Changes in these genes cause rare conditions in which Hypothermia is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| BRAT1BRCA1 associated ATM activator 1 | Always | In 1 condition |
| COA6cytochrome c oxidase assembly factor 6 | Always | In 1 condition |
| COQ9coenzyme Q9 | Always | In 1 condition |
| GABRA2gamma-aminobutyric acid type A receptor subunit alpha2 | Always | In 1 condition |
| KDM6Blysine demethylase 6B | Always | In 1 condition |
| MICOS13mitochondrial contact site and cristae organizing system subunit 13 | Always | In 1 condition |
| SLC52A1solute carrier family 52 member 1 | Always | In 1 condition |
| SUCLG1succinate-CoA ligase GDP/ADP-forming subunit alpha | Always | In 2 conditions |
| UQCRFS1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | Always | In 1 condition |
| TSPYL1TSPY like 1 | Very often (80–99%) | In 2 conditions |
| ATP7AATPase copper transporting alpha | Often (30–79%) | In 3 conditions |
| HESX1HESX homeobox 1 | Often (30–79%) | In 1 condition |
| LHX3LIM homeobox 3 | Often (30–79%) | In 1 condition |
| LHX4LIM homeobox 4 | Often (30–79%) | In 1 condition |
| NAGSN-acetylglutamate synthase | Often (30–79%) | In 1 condition |
| OTCornithine transcarbamylase | Often (30–79%) | In 1 condition |
| POU1F1POU class 1 homeobox 1 | Often (30–79%) | In 1 condition |
| PROP1PROP paired-like homeobox 1 | Often (30–79%) | In 1 condition |
| TSHBthyroid stimulating hormone subunit beta | Often (30–79%) | In 1 condition |
| ACADVLacyl-CoA dehydrogenase very long chain | Sometimes (5–29%) | In 1 condition |
| CACNA1Ccalcium voltage-gated channel subunit alpha1 C | Sometimes (5–29%) | In 1 condition |
| CD28CD28 molecule | Sometimes (5–29%) | In 1 condition |
| CRELD1CRELD disulfide isomerase 1 | Sometimes (5–29%) | In 1 condition |
| CTLA4cytotoxic T-lymphocyte associated protein 4 | Sometimes (5–29%) | In 1 condition |
| DBHdopamine beta-hydroxylase | Sometimes (5–29%) | In 1 condition |
| DUOX2dual oxidase 2 | Sometimes (5–29%) | In 2 conditions |
| DUOXA2dual oxidase maturation factor 2 | Sometimes (5–29%) | In 1 condition |
| IVDisovaleryl-CoA dehydrogenase | Sometimes (5–29%) | In 1 condition |
| IYDiodotyrosine deiodinase | Sometimes (5–29%) | In 1 condition |
| LMNB1lamin B1 | Sometimes (5–29%) | In 1 condition |
| MMACHCmetabolism of cobalamin associated C | Sometimes (5–29%) | In 1 condition |
| MT-ATP6mitochondrially encoded ATP synthase membrane subunit 6 | Sometimes (5–29%) | In 1 condition |
| MT-ND1mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 | Sometimes (5–29%) | In 1 condition |
| MT-ND2mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 | Sometimes (5–29%) | In 1 condition |
| MT-ND3mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 | Sometimes (5–29%) | In 1 condition |
| MT-ND4mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 | Sometimes (5–29%) | In 1 condition |
| MT-ND5mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 | Sometimes (5–29%) | In 1 condition |
| MT-ND6mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 | Sometimes (5–29%) | In 1 condition |
| MT-TKmitochondrially encoded tRNA-Lys (AAA/G) | Sometimes (5–29%) | In 1 condition |
| MT-TL1mitochondrially encoded tRNA-Leu (UUA/G) 1 | Sometimes (5–29%) | In 1 condition |
Show 19 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| MT-TVmitochondrially encoded tRNA-Val (GUN) | Sometimes (5–29%) | In 1 condition |
| MT-TWmitochondrially encoded tRNA-Trp (UGA/G) | Sometimes (5–29%) | In 1 condition |
| SCN10Asodium voltage-gated channel alpha subunit 10 | Sometimes (5–29%) | In 1 condition |
| SCN11Asodium voltage-gated channel alpha subunit 11 | Sometimes (5–29%) | In 1 condition |
| SCN9Asodium voltage-gated channel alpha subunit 9 | Sometimes (5–29%) | In 1 condition |
| SLC25A20solute carrier family 25 member 20 | Sometimes (5–29%) | In 1 condition |
| SLC5A5solute carrier family 5 member 5 | Sometimes (5–29%) | In 1 condition |
| TBCKTBC1 domain containing kinase | Sometimes (5–29%) | In 1 condition |
| TGthyroglobulin | Sometimes (5–29%) | In 1 condition |
| TNFRSF1BTNF receptor superfamily member 1B | Sometimes (5–29%) | In 1 condition |
| TPOthyroid peroxidase | Sometimes (5–29%) | In 1 condition |
| BTNL2butyrophilin like 2 | Rarely (1–4%) | In 1 condition |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Rarely (1–4%) | In 1 condition |
| HMGCL3-hydroxy-3-methylglutaryl-CoA lyase | Rarely (1–4%) | In 1 condition |
| NTRK1neurotrophic receptor tyrosine kinase 1 | Rarely (1–4%) | In 1 condition |
| TSHRthyroid stimulating hormone receptor | Rarely (1–4%) | In 1 condition |
| ACADSBacyl-CoA dehydrogenase short/branched chain | Not recorded | In 1 condition |
| DGUOKdeoxyguanosine kinase | Not recorded | In 1 condition |
| PAX8paired box 8 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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