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Gene

TTLL3

tubulin tyrosine ligase like 3

Summary

Cytogenetic location
3p25.3
Coordinates
Chromosome 3: 9,810,262–9,836,365 (GRCh38)
Exons
14 exons across 26.1 kb
Protein
815 amino acids
Also known as
DKFZP434B103, HOTTL
MANE Select transcript
ENST00000685419.1NM_001387446.1
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TTLL3 yet. The test sequences your whole genome, so your data includes it all the same.

How TTLL3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 3, with a bracket where TTLL3 sits. TTLL3 and 31 genes near it on chromosome 3, from 9,323,314 to 10,323,313.Chromosome 33p25.3p26.3p26.2p26.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13.11q13.12q13.13q13.2q13.31q13.32q13.33q21.1q21.2q21.3q22.1q22.2q22.3q23q24q25.1q25.2q25.31q25.32q25.33q26.1q26.2q26.31q26.32q26.33q27.1q27.2q27.3q28q299.4 Mb9.6 Mb9.8 Mb10 Mb10.2 MbSRGAP3: 8,980,591–9,363,053, reverse strandSRGAP3THUMPD3: 9,362,967–9,389,323, forward strandTHUMPD3SETD5: 9,397,609–9,479,240, forward strandSETD5LHFPL4: 9,498,361–9,553,862, reverse strandLHFPL4MTMR14: 9,649,307–9,702,394, forward strandMTMR14CPNE9: 9,703,691–9,729,908, forward strandCPNE9BRPF1: 9,731,726–9,748,019, forward strandBRPF1OGG1: 9,749,938–9,791,067, forward strandOGG1CAMK1: 9,757,341–9,770,606, reverse strandTADA3: 9,779,964–9,793,011, reverse strandARPC4: 9,792,484–9,807,704, forward strandARPC4ARPC4-TTLL3: 9,793,082–9,835,401, forward strandARPC4-TTLL3TTLL3: 9,810,262–9,836,365, forward strandTTLL3RPUSD3: 9,831,633–9,844,602, reverse strandRPUSD3CIDEC: 9,864,169–9,891,008, reverse strandCIDECJAGN1: 9,890,569–9,894,349, forward strandJAGN1IL17RE: 9,902,612–9,916,402, forward strandIL17REIL17RC: 9,917,040–9,933,630, forward strandIL17RC: 9,917,116–9,945,385, forward strandCRELD1: 9,933,791–9,945,413, forward strandPRRT3: 9,939,450–9,952,442, reverse strandEMC3: 9,957,217–10,011,202, reverse strandEMC3FANCD2: 10,026,370–10,101,937, forward strandFANCD2FANCD2OS: 10,081,317–10,108,290, reverse strandFANCD2OSBRK1: 10,115,590–10,135,082, forward strandBRK1VHL: 10,141,764–10,153,676, forward strandVHLIRAK2: 10,164,862–10,243,756, forward strandIRAK2TATDN2: 10,248,023–10,281,218, forward strandTATDN2: 10,249,042–10,249,366, forward strand: 10,249,372–10,285,796, forward strandGHRL: 10,285,666–10,292,959, reverse strandGHRLSEC13: 10,293,131–10,321,207, reverse strandSEC13Diagram of TTLL3: 14 exons on the forward strand of chromosome 3Exon 1: 9,810,262–9,810,394, 133 basesExon 2: 9,810,621–9,810,709, 89 basesExon 3: 9,812,943–9,813,111, 169 basesExon 4: 9,813,248–9,813,345, 98 basesExon 5: 9,816,074–9,816,202, 129 basesExon 6: 9,817,645–9,817,759, 115 basesExon 7: 9,818,822–9,818,920, 99 basesExon 8: 9,820,546–9,820,741, 196 basesExon 9: 9,825,800–9,825,948, 149 basesExon 10: 9,826,997–9,827,240, 244 basesExon 11: 9,828,960–9,829,395, 436 basesExon 12: 9,833,104–9,833,245, 142 basesExon 13: 9,834,681–9,834,907, 227 basesExon 14: 9,835,094–9,836,365, 1,272 bases1510145′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.5 kb of the gene's 26.1 kb; 2,448 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). TTLL3 gene: tubulin tyrosine ligase like 3. Retrieved 17 October 2026, from https://dantelabs.com/genes/ttll3

Vancouver

Dante Labs. TTLL3 gene: tubulin tyrosine ligase like 3 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/ttll3

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