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Gene

ARPC4

actin related protein 2/3 complex subunit 4

Summary

Cytogenetic location
3p25.3
Coordinates
Chromosome 3: 9,793,082–9,807,101 (GRCh38)
Exons
6 exons across 14 kb
Protein
168 amino acids
Also known as
p20-Arc, ARC20
MANE Select transcript
ENST00000397261.8NM_005718.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads ARPC4 yet. The test sequences your whole genome, so your data includes it all the same.

How ARPC4 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 3, with a bracket where ARPC4 sits. ARPC4 and 31 genes near it on chromosome 3, from 9,300,092 to 10,300,091.Chromosome 33p25.3p26.3p26.2p26.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13.11q13.12q13.13q13.2q13.31q13.32q13.33q21.1q21.2q21.3q22.1q22.2q22.3q23q24q25.1q25.2q25.31q25.32q25.33q26.1q26.2q26.31q26.32q26.33q27.1q27.2q27.3q28q299.4 Mb9.6 Mb9.8 Mb10 Mb10.2 MbSRGAP3: 8,980,591–9,363,053, reverse strandSRGAP3THUMPD3: 9,362,967–9,389,323, forward strandTHUMPD3SETD5: 9,397,609–9,479,240, forward strandSETD5LHFPL4: 9,498,361–9,553,862, reverse strandLHFPL4MTMR14: 9,649,307–9,702,394, forward strandMTMR14CPNE9: 9,703,691–9,729,908, forward strandCPNE9BRPF1: 9,731,726–9,748,019, forward strandOGG1: 9,749,938–9,791,067, forward strandOGG1CAMK1: 9,757,341–9,770,606, reverse strandTADA3: 9,779,964–9,793,011, reverse strandTADA3ARPC4: 9,793,082–9,807,101, forward strandARPC4ARPC4-TTLL3: 9,793,082–9,835,401, forward strandARPC4-TTLL3TTLL3: 9,808,086–9,856,087, forward strandTTLL3RPUSD3: 9,831,633–9,844,602, reverse strandCIDEC: 9,864,169–9,891,008, reverse strandCIDECJAGN1: 9,890,569–9,894,349, forward strandJAGN1IL17RE: 9,902,612–9,916,402, forward strandIL17REIL17RC: 9,917,040–9,933,630, forward strandIL17RC: 9,917,116–9,945,385, forward strandCRELD1: 9,933,791–9,945,413, forward strandPRRT3: 9,939,450–9,952,442, reverse strandEMC3: 9,957,217–10,011,202, reverse strandEMC3FANCD2: 10,026,370–10,101,937, forward strandFANCD2FANCD2OS: 10,081,317–10,108,290, reverse strandFANCD2OSBRK1: 10,115,590–10,135,082, forward strandBRK1VHL: 10,141,764–10,153,676, forward strandVHLIRAK2: 10,164,862–10,243,756, forward strandIRAK2TATDN2: 10,248,023–10,281,218, forward strandTATDN2: 10,249,042–10,249,366, forward strand: 10,249,372–10,285,796, forward strandGHRL: 10,285,666–10,292,959, reverse strandGHRLSEC13: 10,293,131–10,321,207, reverse strandSEC13Diagram of ARPC4: 6 exons on the forward strand of chromosome 3Exon 5: 1 known disease-causing siteExon 1: 9,793,082–9,793,124, 43 basesExon 2: 9,797,659–9,797,777, 119 basesExon 3: 9,800,185–9,800,296, 112 basesExon 4: 9,801,661–9,801,756, 96 basesExon 5: 9,803,843–9,804,013, 171 basesExon 6: 9,806,210–9,807,101, 892 bases1234565′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.4 kb of the gene's 14 kb; 507 of those bases code for the protein.

How a genome test reads ARPC4

1

position in ARPC4 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 14 kb of ARPC4, introns included, not only the 1.4 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). ARPC4 gene: actin related protein 2/3 complex subunit 4. Retrieved 17 October 2026, from https://dantelabs.com/genes/arpc4

Vancouver

Dante Labs. ARPC4 gene: actin related protein 2/3 complex subunit 4 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/arpc4

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