Trait
Papule
A circumscribed, solid elevation of skin with no visible fluid, varying in size from a pinhead to less than 10mm in diameter at the widest point.
Summary
- Also called
- Papules
- Body system
- Abnormality of the integument
Reference genomeGRCh38hg38
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Get my Genome Test69 genes linked to Papule
Changes in these genes cause rare conditions in which Papule is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| EGFRepidermal growth factor receptor | Always | In 1 condition |
| FDXRferredoxin reductase | Always | In 1 condition |
| IRF4interferon regulatory factor 4 | Always | In 1 condition |
| LRP1LDL receptor related protein 1 | Always | In 1 condition |
| PIGAphosphatidylinositol glycan anchor biosynthesis class A | Always | In 1 condition |
| SPINK5serine peptidase inhibitor Kazal type 5 | Always | In 1 condition |
| SUFUSUFU negative regulator of hedgehog signaling | Always | In 1 condition |
| ANTXR2ANTXR cell adhesion molecule 2 | Very often (80–99%) | In 1 condition |
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Very often (80–99%) | In 1 condition |
| C4Acomplement C4A (Chido/Rodgers blood group) | Very often (80–99%) | In 1 condition |
| CARD14caspase recruitment domain family member 14 | Very often (80–99%) | In 1 condition |
| CCR1C-C motif chemokine receptor 1 | Very often (80–99%) | In 1 condition |
| CIB1calcium and integrin binding 1 | Very often (80–99%) | In 1 condition |
| CYLDCYLD lysine 63 deubiquitinase | Very often (80–99%) | In 1 condition |
| ECM1extracellular matrix protein 1 | Very often (80–99%) | In 2 conditions |
| ELOVL4ELOVL fatty acid elongase 4 | Very often (80–99%) | In 1 condition |
| ERAP1endoplasmic reticulum aminopeptidase 1 | Very often (80–99%) | In 1 condition |
| FASFas cell surface death receptor | Very often (80–99%) | In 1 condition |
| GGCXgamma-glutamyl carboxylase | Very often (80–99%) | In 2 conditions |
| HLA-Bmajor histocompatibility complex, class I, B | Very often (80–99%) | In 1 condition |
| IFNGR1interferon gamma receptor 1 | Very often (80–99%) | In 1 condition |
| IL10interleukin 10 | Very often (80–99%) | In 1 condition |
| IL12Ainterleukin 12A | Very often (80–99%) | In 1 condition |
| IL12A-AS1IL12A antisense RNA 1 | Very often (80–99%) | In 1 condition |
| IL23Rinterleukin 23 receptor | Very often (80–99%) | In 1 condition |
| IL7interleukin 7 | Very often (80–99%) | In 1 condition |
| KLRC4killer cell lectin like receptor C4 | Very often (80–99%) | In 1 condition |
| LPIN2lipin 2 | Very often (80–99%) | In 1 condition |
| MBTPS2membrane bound transcription factor peptidase, site 2 | Very often (80–99%) | In 1 condition |
| MEFVMEFV innate immunity regulator, pyrin | Very often (80–99%) | In 1 condition |
| NAGAalpha-N-acetylgalactosaminidase | Very often (80–99%) | In 1 condition |
| NLRP3NLR family pyrin domain containing 3 | Very often (80–99%) | In 1 condition |
| NOD2nucleotide binding oligomerization domain containing 2 | Very often (80–99%) | In 1 condition |
| PEPDpeptidase D | Very often (80–99%) | In 1 condition |
| PTENphosphatase and tensin homolog | Very often (80–99%) | In 3 conditions |
| STAT4signal transducer and activator of transcription 4 | Very often (80–99%) | In 1 condition |
| TLR4toll like receptor 4 | Very often (80–99%) | In 1 condition |
| TMC6transmembrane channel like 6 | Very often (80–99%) | In 1 condition |
| TMC8transmembrane channel like 8 | Very often (80–99%) | In 1 condition |
| UBAC2UBA domain containing 2 | Very often (80–99%) | In 1 condition |
Show 29 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| AQP5aquaporin 5 | Often (30–79%) | In 1 condition |
| CLEC7AC-type lectin domain containing 7A | Often (30–79%) | In 1 condition |
| CTLA4cytotoxic T-lymphocyte associated protein 4 | Often (30–79%) | In 1 condition |
| GNAQG protein subunit alpha q | Often (30–79%) | In 1 condition |
| HLA-DPA1major histocompatibility complex, class II, DP alpha 1 | Often (30–79%) | In 1 condition |
| HLA-DPB1major histocompatibility complex, class II, DP beta 1 | Often (30–79%) | In 1 condition |
| IL17Finterleukin 17F | Often (30–79%) | In 1 condition |
| IL17RAinterleukin 17 receptor A | Often (30–79%) | In 1 condition |
| IL17RCinterleukin 17 receptor C | Often (30–79%) | In 1 condition |
| MVKmevalonate kinase | Often (30–79%) | In 1 condition |
| NF1neurofibromin 1 | Often (30–79%) | In 1 condition |
| PLECplectin | Often (30–79%) | In 1 condition |
| PRTN3proteinase 3 | Often (30–79%) | In 1 condition |
| PTPN22protein tyrosine phosphatase non-receptor type 22 | Often (30–79%) | In 1 condition |
| STAT3signal transducer and activator of transcription 3 | Often (30–79%) | In 1 condition |
| TRAF3IP2TRAF3 interacting protein 2 | Often (30–79%) | In 1 condition |
| COL7A1collagen type VII alpha 1 chain | Sometimes (5–29%) | In 1 condition |
| CSTAcystatin A | Sometimes (5–29%) | In 1 condition |
| GJB2gap junction protein beta 2 | Sometimes (5–29%) | In 1 condition |
| GLMNglomulin, FKBP associated protein | Sometimes (5–29%) | In 1 condition |
| GNASGNAS complex locus | Sometimes (5–29%) | In 1 condition |
| LMNAlamin A/C | Sometimes (5–29%) | In 1 condition |
| TGM5transglutaminase 5 | Sometimes (5–29%) | In 1 condition |
| ZMPSTE24zinc metallopeptidase STE24 | Sometimes (5–29%) | In 1 condition |
| KRT14keratin 14 | Rarely (1–4%) | In 1 condition |
| KRT5keratin 5 | Rarely (1–4%) | In 1 condition |
| ERCC4ERCC excision repair 4, endonuclease catalytic subunit | Not recorded | In 1 condition |
| POGLUT1protein O-glucosyltransferase 1 | Not recorded | In 1 condition |
| SLC17A9solute carrier family 17 member 9 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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