Trait
Hyperpigmented papule
A papule (circumscribed, solid elevation of skin with no visible fluid, varying in size from a pinhead to less than 10mm in diameter at the widest point) that exhibits increased pigmentation (is darker) compared to the surrounding skin.
Summary
- Body system
- Abnormality of the integument
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Hyperpigmented papule, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test9 genes linked to Hyperpigmented papule
Changes in these genes cause rare conditions in which Hyperpigmented papule is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| FLNAfilamin A | Very often (80–99%) | In 1 condition |
| ABCC6ATP binding cassette subfamily C member 6 | Often (30–79%) | In 1 condition |
| ENPP1ectonucleotide pyrophosphatase/phosphodiesterase 1 | Often (30–79%) | In 1 condition |
| KITKIT proto-oncogene, receptor tyrosine kinase | Often (30–79%) | In 1 condition |
| IDH1isocitrate dehydrogenase (NADP(+)) 1 | Sometimes (5–29%) | In 1 condition |
| KRT5keratin 5 | Sometimes (5–29%) | In 1 condition |
| POFUT1protein O-fucosyltransferase 1 | Sometimes (5–29%) | In 1 condition |
| POGLUT1protein O-glucosyltransferase 1 | Sometimes (5–29%) | In 1 condition |
| PSENENpresenilin enhancer, gamma-secretase subunit | Sometimes (5–29%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks