Trait
Incoordination
A deficit in coordination of muscle movements. Coordination is defined as the orchestrated movement of multiple body parts as required to accomplish intended actions, like walking.
Summary
- Also called
- Difficulties in coordination, Incoordination of limb movements, Limb incoordination, Poor coordination, Poor motor coordination
- Body system
- Abnormality of the nervous system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test115 genes linked to Incoordination
Changes in these genes cause rare conditions in which Incoordination is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ABCA2ATP binding cassette subfamily A member 2 | Always | In 1 condition |
| ATP9AATPase phospholipid transporting 9A | Always | In 1 condition |
| CREBBPCREB binding lysine acetyltransferase | Always | In 1 condition |
| EEF1A2eukaryotic translation elongation factor 1 alpha 2 | Always | In 1 condition |
| EP300EP300 lysine acetyltransferase | Always | In 1 condition |
| ERCC4ERCC excision repair 4, endonuclease catalytic subunit | Always | In 1 condition |
| GRID2glutamate ionotropic receptor delta type subunit 2 | Always | In 1 condition |
| JPH1junctophilin 1 | Always | In 1 condition |
| LRRC7leucine rich repeat containing 7 | Always | In 1 condition |
| MCCC1methylcrotonyl-CoA carboxylase subunit 1 | Always | In 1 condition |
| MPV17mitochondrial inner membrane protein MPV17 | Always | In 1 condition |
| MSL2MSL complex subunit 2 | Always | In 1 condition |
| NADK2NAD kinase 2, mitochondrial | Always | In 1 condition |
| PANK2pantothenate kinase 2 | Always | In 1 condition |
| PDE2Aphosphodiesterase 2A | Always | In 1 condition |
| PPP2R5Cprotein phosphatase 2 regulatory subunit B'gamma | Always | In 1 condition |
| RNU2-2RNA, U2 small nuclear 2 | Always | In 1 condition |
| RPIAribose 5-phosphate isomerase A | Always | In 1 condition |
| RRP12ribosomal RNA processing 12 homolog | Always | In 1 condition |
| SIN3ASIN3 transcription regulator family member A | Always | In 1 condition |
| SLC18A2solute carrier family 18 member A2 | Always | In 1 condition |
| TINF2TERF1 interacting nuclear factor 2 | Always | In 1 condition |
| CACNA1Acalcium voltage-gated channel subunit alpha1 A | Very often (80–99%) | In 2 conditions |
| KCNA1potassium voltage-gated channel subfamily A member 1 | Very often (80–99%) | In 2 conditions |
| SPTBN2spectrin beta, non-erythrocytic 2 | Very often (80–99%) | In 2 conditions |
| TXN2thioredoxin 2 | Very often (80–99%) | In 1 condition |
| BSCL2BSCL2 lipid droplet biogenesis associated, seipin | Often (30–79%) | In 1 condition |
| CHAMP1chromosome alignment maintaining phosphoprotein 1 | Often (30–79%) | In 1 condition |
| CPLX1complexin 1 | Often (30–79%) | In 1 condition |
| DYRK1Adual specificity tyrosine phosphorylation regulated kinase 1A | Often (30–79%) | In 1 condition |
| ELNelastin | Often (30–79%) | In 1 condition |
| GCDHglutaryl-CoA dehydrogenase | Often (30–79%) | In 1 condition |
| GCH1GTP cyclohydrolase 1 | Often (30–79%) | In 1 condition |
| HEXBhexosaminidase subunit beta | Often (30–79%) | In 1 condition |
| LZTFL1leucine zipper transcription factor like 1 | Often (30–79%) | In 1 condition |
| MLXIPLMLX interacting protein like | Often (30–79%) | In 1 condition |
| MTFMTmitochondrial methionyl-tRNA formyltransferase | Often (30–79%) | In 1 condition |
| PMPCApeptidase, mitochondrial processing subunit alpha | Often (30–79%) | In 2 conditions |
| RDH11retinol dehydrogenase 11 | Often (30–79%) | In 1 condition |
| RFC4replication factor C subunit 4 | Often (30–79%) | In 1 condition |
Show 75 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| SCN8Asodium voltage-gated channel alpha subunit 8 | Often (30–79%) | In 1 condition |
| SLC25A15solute carrier family 25 member 15 | Often (30–79%) | In 2 conditions |
| SPG7SPG7 matrix AAA peptidase subunit, paraplegin | Often (30–79%) | In 1 condition |
| SYNGAP1synaptic Ras GTPase activating protein 1 | Often (30–79%) | In 1 condition |
| TANGO2transport and golgi organization 2 homolog | Often (30–79%) | In 2 conditions |
| TBC1D24TBC1 domain family member 24 | Often (30–79%) | In 1 condition |
| TPRtranslocated promoter region, nuclear basket protein | Often (30–79%) | In 1 condition |
| VPS13Avacuolar protein sorting 13 homolog A | Often (30–79%) | In 1 condition |
| AASSaminoadipate-semialdehyde synthase | Sometimes (5–29%) | In 1 condition |
| ADGRV1adhesion G protein-coupled receptor V1 | Sometimes (5–29%) | In 1 condition |
| AFF2ALF transcription elongation factor 2 | Sometimes (5–29%) | In 1 condition |
| ALMS1ALMS1 centrosome and basal body associated protein | Sometimes (5–29%) | In 1 condition |
| APC2APC regulator of Wnt signaling pathway 2 | Sometimes (5–29%) | In 1 condition |
| ATP1A3ATPase Na+/K+ transporting subunit alpha 3 | Sometimes (5–29%) | In 1 condition |
| CARS1cysteinyl-tRNA synthetase 1 | Sometimes (5–29%) | In 1 condition |
| CDC42BPBCDC42 binding protein kinase beta | Sometimes (5–29%) | In 1 condition |
| CPA6carboxypeptidase A6 | Sometimes (5–29%) | In 1 condition |
| FGF13fibroblast growth factor 13 | Sometimes (5–29%) | In 1 condition |
| GABRA1gamma-aminobutyric acid type A receptor subunit alpha1 | Sometimes (5–29%) | In 1 condition |
| GABRDgamma-aminobutyric acid type A receptor subunit delta | Sometimes (5–29%) | In 1 condition |
| GABRG2gamma-aminobutyric acid type A receptor subunit gamma2 | Sometimes (5–29%) | In 2 conditions |
| GALTgalactose-1-phosphate uridylyltransferase | Sometimes (5–29%) | In 1 condition |
| GJB1gap junction protein beta 1 | Sometimes (5–29%) | In 1 condition |
| HCN1hyperpolarization activated cyclic nucleotide gated potassium channel 1 | Sometimes (5–29%) | In 1 condition |
| HSD17B10hydroxysteroid 17-beta dehydrogenase 10 | Sometimes (5–29%) | In 1 condition |
| KCND3potassium voltage-gated channel subfamily D member 3 | Sometimes (5–29%) | In 1 condition |
| LYSTlysosomal trafficking regulator | Sometimes (5–29%) | In 1 condition |
| MED13Lmediator complex subunit 13L | Sometimes (5–29%) | In 1 condition |
| MORC2MORC family CW-type zinc finger 2 | Sometimes (5–29%) | In 1 condition |
| NAA20N-alpha-acetyltransferase 20, NatB catalytic subunit | Sometimes (5–29%) | In 1 condition |
| NIPA1NIPA magnesium transporter 1 | Sometimes (5–29%) | In 1 condition |
| NIPA2NIPA magnesium transporter 2 | Sometimes (5–29%) | In 1 condition |
| NKX2-1NK2 homeobox 1 | Sometimes (5–29%) | In 1 condition |
| NSD1nuclear receptor binding SET domain protein 1 | Sometimes (5–29%) | In 2 conditions |
| PCDH19protocadherin 19 | Sometimes (5–29%) | In 1 condition |
| PRNPprion protein (Kanno blood group) | Sometimes (5–29%) | In 2 conditions |
| PRRT2proline rich transmembrane protein 2 | Sometimes (5–29%) | In 1 condition |
| RORARAR related orphan receptor A | Sometimes (5–29%) | In 1 condition |
| SCN1Asodium voltage-gated channel alpha subunit 1 | Sometimes (5–29%) | In 2 conditions |
| SCN1Bsodium voltage-gated channel beta subunit 1 | Sometimes (5–29%) | In 2 conditions |
| SCN2Asodium voltage-gated channel alpha subunit 2 | Sometimes (5–29%) | In 2 conditions |
| SCN9Asodium voltage-gated channel alpha subunit 9 | Sometimes (5–29%) | In 2 conditions |
| SETSET nuclear proto-oncogene | Sometimes (5–29%) | In 1 condition |
| SIM1SIM bHLH transcription factor 1 | Sometimes (5–29%) | In 1 condition |
| SLC32A1solute carrier family 32 member 1 | Sometimes (5–29%) | In 1 condition |
| STX1Bsyntaxin 1B | Sometimes (5–29%) | In 1 condition |
| TTC19tetratricopeptide repeat domain 19 | Sometimes (5–29%) | In 1 condition |
| TUBG1tubulin gamma 1 | Sometimes (5–29%) | In 1 condition |
| YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma | Sometimes (5–29%) | In 1 condition |
| POGZpogo transposable element derived with ZNF domain | Rarely (1–4%) | In 1 condition |
| ABCD1ATP binding cassette subfamily D member 1 | Not recorded | In 1 condition |
| ARL6ARF like GTPase 6 | Not recorded | In 1 condition |
| ATP7BATPase copper transporting beta | Not recorded | In 1 condition |
| ATXN10ataxin 10 | Not recorded | In 1 condition |
| ATXN8ataxin 8 | Not recorded | In 1 condition |
| ATXN8OSATXN8 opposite strand lncRNA | Not recorded | In 1 condition |
| BBS1Bardet-Biedl syndrome 1 | Not recorded | In 1 condition |
| BMPR1Bbone morphogenetic protein receptor type 1B | Not recorded | In 1 condition |
| CCDC28Bcoiled-coil domain containing 28B | Not recorded | In 1 condition |
| EEDembryonic ectoderm development | Not recorded | In 1 condition |
| EEF2eukaryotic translation elongation factor 2 | Not recorded | In 1 condition |
| ELP1elongator acetyltransferase complex subunit 1 | Not recorded | In 1 condition |
| FXNfrataxin | Not recorded | In 1 condition |
| HLA-DQB1major histocompatibility complex, class II, DQ beta 1 | Not recorded | In 1 condition |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Not recorded | In 1 condition |
| HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 | Not recorded | In 1 condition |
| LMBRD1LMBR1 domain containing 1 | Not recorded | In 1 condition |
| MTHFRmethylenetetrahydrofolate reductase | Not recorded | In 1 condition |
| MTR5-methyltetrahydrofolate-homocysteine methyltransferase | Not recorded | In 1 condition |
| NOP56NOP56 ribonucleoprotein | Not recorded | In 1 condition |
| SPG21SPG21 abhydrolase domain containing, maspardin | Not recorded | In 1 condition |
| TBC1D23TBC1 domain family member 23 | Not recorded | In 1 condition |
| TCF20transcription factor 20 | Not recorded | In 1 condition |
| TCF4transcription factor 4 | Not recorded | In 1 condition |
| TGM6transglutaminase 6 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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