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Gene

HSD17B10

hydroxysteroid 17-beta dehydrogenase 10

Summary

Cytogenetic location
Xp11.22
Coordinates
Chromosome X: 53,431,261–53,434,370 (GRCh38)
Exons
6 exons across 3.1 kb
Protein
261 amino acids
Also known as
ERAB, MHBD, 17b-HSD10, ABAD, SDR5C1, MRPP2, CAMR
Previous symbols
HADH2, MRXS10
MANE Select transcript
ENST00000168216.11NM_004493.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads HSD17B10 yet. The test sequences your whole genome, so your data includes it all the same.

How HSD17B10 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
Chromosome X, with a bracket where HSD17B10 sits. HSD17B10 and 9 genes near it on chromosome X, from 52,932,816 to 53,932,815.Chromosome XXp11.22p22.33p22.32p22.31p22.2p22.13p22.12p22.11p21.3p21.2p21.1p11.4p11.3p11.23p11.22p11.21p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.31q21.32q21.33q22.1q22.2q22.3q23q24q25q26.1q26.2q26.3q27.1q27.2q27.3q2853 Mb53.2 Mb53.4 Mb53.6 Mb53.8 MbFAM156A: 52,926,402–52,995,564, reverse strandFAM156AGPR173: 53,048,783–53,080,615, forward strandGPR173TSPYL2: 53,081,937–53,088,542, forward strandTSPYL2KANTR: 53,094,092–53,170,914, forward strandKANTRKDM5C: 53,176,277–53,225,422, reverse strandKDM5CIQSEC2: 53,225,828–53,321,396, reverse strandIQSEC2SMC1A: 53,361,522–53,422,750, reverse strandSMC1ARIBC1: 53,421,951–53,431,624, forward strandRIBC1HSD17B10: 53,431,261–53,434,370, reverse strandHSD17B10HUWE1: 53,532,096–53,686,752, reverse strandHUWE1Diagram of HSD17B10: 6 exons on the reverse strand of chromosome XExon 6: 3 known disease-causing sitesExon 5: 5 known disease-causing sitesExon 4: 2 known disease-causing sitesExon 2: 3 known disease-causing sitesExon 6: 53,431,261–53,431,594, 334 basesExon 5: 53,431,798–53,431,906, 109 basesExon 4: 53,431,988–53,432,116, 129 basesExon 3: 53,432,247–53,432,411, 165 basesExon 2: 53,433,722–53,433,886, 165 basesExon 1: 53,434,319–53,434,370, 52 bases6543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1 kb of the gene's 3.1 kb; 786 of those bases code for the protein.

How a genome test reads HSD17B10

13

positions in HSD17B10 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 3.1 kb of HSD17B10, introns included, not only the 1 kb of exons.

Traits linked to HSD17B10

The Human Phenotype Ontology lists these as features of the rare conditions HSD17B10 can cause. Each trait's page lists the other genes linked to it.

Abnormality of the nervous system

Show 22 more traits

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). HSD17B10 gene: hydroxysteroid 17-beta dehydrogenase 10. Retrieved 17 October 2026, from https://dantelabs.com/genes/hsd17b10

Vancouver

Dante Labs. HSD17B10 gene: hydroxysteroid 17-beta dehydrogenase 10 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/hsd17b10

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