Gene
TXN2
thioredoxin 2
- HGNC 17772↗(opens in a new tab)
- Ensembl gene ENSG00000100348↗(opens in a new tab)
- NCBI Gene 25828↗(opens in a new tab)
Summary
- Cytogenetic location
- 22q12.3
- Coordinates
- Chromosome 22: 36,467,046–36,481,640 (GRCh38)
- Exons
- 4 exons across 14.6 kb
- Protein
- 166 amino acids
- Also known as
- MT-TRX
- MANE Select transcript
- ENST00000216185.7NM_012473.4
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How TXN2 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 1.3 kb of the gene's 14.6 kb; 501 of those bases code for the protein.
Traits linked to TXN2
The Human Phenotype Ontology lists these as features of the rare conditions TXN2 can cause. Each trait's page lists the other genes linked to it.
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). TXN2 gene: thioredoxin 2. Retrieved 16 October 2026, from https://dantelabs.com/genes/txn2
Dante Labs. TXN2 gene: thioredoxin 2 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/txn2
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