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Gene

PDE2A

phosphodiesterase 2A

Summary

Cytogenetic location
11q13.4
Coordinates
Chromosome 11: 72,576,141–72,674,422 (GRCh38)
Exons
31 exons across 98.3 kb
Protein
941 amino acids
MANE Select transcript
ENST00000334456.10NM_002599.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PDE2A yet. The test sequences your whole genome, so your data includes it all the same.

How PDE2A is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 11, with a bracket where PDE2A sits. PDE2A and 10 genes near it on chromosome 11, from 72,125,282 to 73,125,281.Chromosome 1111q13.4p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q2572.2 Mb72.4 Mb72.6 Mb72.8 Mb73 MbFOLR3: 72,114,869–72,141,085, forward strandFOLR3FOLR1: 72,189,529–72,199,329, forward strandFOLR1FOLR2: 72,216,601–72,221,957, forward strandFOLR2INPPL1: 72,223,524–72,239,184, forward strandINPPL1PHOX2A: 72,239,077–72,245,664, reverse strandPHOX2ACLPB: 72,285,495–72,434,680, reverse strandCLPBPDE2A: 72,576,141–72,674,422, reverse strandPDE2AARAP1: 72,682,436–72,794,047, reverse strandARAP1STARD10: 72,753,216–72,794,047, reverse strandSTARD10ATG16L2: 72,814,138–72,845,036, forward strandATG16L2FCHSD2: 72,836,042–73,142,485, reverse strandFCHSD2Diagram of PDE2A: 31 exons on the reverse strand of chromosome 11Exon 31: 72,576,141–72,577,594, 1,454 basesExon 30: 72,578,233–72,578,339, 107 basesExon 29: 72,578,476–72,578,514, 39 basesExon 28: 72,578,897–72,579,009, 113 basesExon 27: 72,579,284–72,579,383, 100 basesExon 26: 72,579,534–72,579,608, 75 basesExon 25: 72,580,577–72,580,624, 48 basesExon 24: 72,580,886–72,580,973, 88 basesExon 23: 72,581,357–72,581,479, 123 basesExon 22: 72,581,877–72,581,947, 71 basesExon 21: 72,582,444–72,582,566, 123 basesExon 20: 72,583,438–72,583,515, 78 basesExon 19: 72,584,201–72,584,313, 113 basesExon 18: 72,584,551–72,584,728, 178 basesExon 17: 72,584,872–72,584,944, 73 basesExon 16: 72,585,371–72,585,434, 64 basesExon 15: 72,585,554–72,585,593, 40 basesExon 14: 72,586,070–72,586,181, 112 basesExon 13: 72,588,784–72,588,914, 131 basesExon 12: 72,589,175–72,589,240, 66 basesExon 11: 72,589,751–72,589,792, 42 basesExon 10: 72,589,907–72,589,981, 75 basesExon 9: 72,590,192–72,590,244, 53 basesExon 8: 72,590,427–72,590,580, 154 basesExon 7: 72,591,297–72,591,356, 60 basesExon 6: 72,596,593–72,596,648, 56 basesExon 5: 72,597,510–72,597,619, 110 basesExon 4: 72,605,138–72,605,226, 89 basesExon 3: 72,608,662–72,608,751, 90 basesExon 2: 72,642,254–72,642,326, 73 basesExon 1: 72,674,137–72,674,422, 286 bases312015′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.3 kb of the gene's 98.3 kb; 2,826 of those bases code for the protein.

How a genome test reads PDE2A

1

position in PDE2A where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 98.3 kb of PDE2A, introns included, not only the 4.3 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). PDE2A gene: phosphodiesterase 2A. Retrieved 16 October 2026, from https://dantelabs.com/genes/pde2a

Vancouver

Dante Labs. PDE2A gene: phosphodiesterase 2A [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/pde2a

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