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Gene

RORA

RAR related orphan receptor A

Summary

Cytogenetic location
15q22.2
Coordinates
Chromosome 15: 60,488,284–61,229,302 (GRCh38)
Exons
11 exons across 741 kb
Protein
523 amino acids
Also known as
RZRA, ROR1, ROR2, ROR3, NR1F1, ROR-alpha, RORalpha, RORa1, RORα
MANE Select transcript
ENST00000335670.11NM_134261.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads RORA yet. The test sequences your whole genome, so your data includes it all the same.

How RORA is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 15, with a bracket where RORA sits. RORA and 4 genes near it on chromosome 15, from 59,747,265 to 61,970,321.Chromosome 1515q22.2p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q14q15.1q15.2q15.3q21.1q21.2q21.3q22.1q22.2q22.31q22.32q22.33q23q24.1q24.2q24.3q25.1q25.2q25.3q26.1q26.2q26.360 Mb60.5 Mb61 Mb61.5 MbFOXB1: 60,004,234–60,061,730, forward strandFOXB1ANXA2: 60,347,134–60,402,883, reverse strandANXA2ICE2: 60,419,608–60,479,160, reverse strandICE2RORA: 60,488,284–61,229,302, reverse strandRORAVPS13C: 61,852,389–62,060,482, reverse strandVPS13CDiagram of RORA: 11 exons on the reverse strand of chromosome 15Exon 10: 3 known disease-causing sitesExon 8: 1 known disease-causing siteExon 7: 3 known disease-causing sitesExon 6: 2 known disease-causing sitesExon 5: 7 known disease-causing sitesExon 4: 1 known disease-causing siteExon 3: 4 known disease-causing sitesExon 11: 60,488,284–60,497,619, 9,336 basesExon 10: 60,499,892–60,500,004, 113 basesExon 9: 60,500,959–60,501,069, 111 basesExon 8: 60,502,760–60,502,867, 108 basesExon 7: 60,503,535–60,503,667, 133 basesExon 6: 60,505,508–60,505,629, 122 basesExon 5: 60,511,226–60,511,621, 396 basesExon 4: 60,514,616–60,514,757, 142 basesExon 3: 60,531,766–60,531,851, 86 basesExon 2: 60,678,657–60,678,686, 30 basesExon 1: 61,229,053–61,229,302, 250 bases1115′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 10.8 kb of the gene's 741 kb; 1,572 of those bases code for the protein.

How a genome test reads RORA

27

positions in RORA where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 741 kb of RORA, introns included, not only the 10.8 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). RORA gene: RAR related orphan receptor A. Retrieved 17 October 2026, from https://dantelabs.com/genes/rora

Vancouver

Dante Labs. RORA gene: RAR related orphan receptor A [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/rora

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