Trait
Heart murmur
An extra or unusual sound heard during a heartbeat caused vibrations resulting from the flow of blood through the heart.
Summary
- Also called
- Heart murmurs, Cardiac murmur, Cardiac murmurs
- Body system
- Abnormality of the cardiovascular system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Heart murmur, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test32 genes linked to Heart murmur
Changes in these genes cause rare conditions in which Heart murmur is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| RNU6ATACRNA, U6atac small nuclear | Always | In 1 condition |
| SCO2synthesis of cytochrome C oxidase 2 | Always | In 1 condition |
| SLC25A4solute carrier family 25 member 4 | Always | In 1 condition |
| FBN1fibrillin 1 | Very often (80–99%) | In 1 condition |
| GATA5GATA binding protein 5 | Very often (80–99%) | In 1 condition |
| NKX2-5NK2 homeobox 5 | Very often (80–99%) | In 1 condition |
| NOTCH1notch receptor 1 | Very often (80–99%) | In 1 condition |
| PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alpha | Very often (80–99%) | In 1 condition |
| ROBO4roundabout guidance receptor 4 | Very often (80–99%) | In 1 condition |
| SMAD6SMAD family member 6 | Very often (80–99%) | In 1 condition |
| ABCG5ATP binding cassette subfamily G member 5 | Often (30–79%) | In 1 condition |
| ABCG8ATP binding cassette subfamily G member 8 | Often (30–79%) | In 1 condition |
| APOBapolipoprotein B | Often (30–79%) | In 1 condition |
| FIG4FIG4 phosphoinositide 5-phosphatase | Often (30–79%) | In 1 condition |
| GAAalpha glucosidase | Often (30–79%) | In 1 condition |
| LDLRlow density lipoprotein receptor | Often (30–79%) | In 1 condition |
| LDLRAP1low density lipoprotein receptor adaptor protein 1 | Often (30–79%) | In 1 condition |
| NIPBLNIPBL cohesin loading factor | Often (30–79%) | In 1 condition |
| PCSK9proprotein convertase subtilisin/kexin type 9 | Often (30–79%) | In 1 condition |
| ADAMTS19ADAM metallopeptidase with thrombospondin type 1 motif 19 | Sometimes (5–29%) | In 1 condition |
| ADNPactivity dependent neuroprotector homeobox | Sometimes (5–29%) | In 1 condition |
| BICRABRD4 interacting chromatin remodeling complex associated protein | Sometimes (5–29%) | In 1 condition |
| CICcapicua transcriptional repressor | Sometimes (5–29%) | In 1 condition |
| CWC27CWC27 spliceosome associated cyclophilin | Sometimes (5–29%) | In 1 condition |
| DDX6DEAD-box helicase 6 | Sometimes (5–29%) | In 1 condition |
| LRRC7leucine rich repeat containing 7 | Sometimes (5–29%) | In 1 condition |
| PEX2peroxisomal biogenesis factor 2 | Sometimes (5–29%) | In 1 condition |
| PSMD12proteasome 26S subunit, non-ATPase 12 | Sometimes (5–29%) | In 1 condition |
| SDHDsuccinate dehydrogenase complex subunit D | Sometimes (5–29%) | In 1 condition |
| SPTBN1spectrin beta, non-erythrocytic 1 | Rarely (1–4%) | In 1 condition |
| GNPTABN-acetylglucosamine-1-phosphate transferase subunits alpha and beta | Not recorded | In 1 condition |
| RBBP8RB binding protein 8, endonuclease | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks