Trait
Stretch marks
Clinical name: Striae distensae
Thinned, erythematous, depressed bands of atrophic skin. Initially, striae appear as flattened and thinned, pinkish linear regions of the skin. Striae tend to enlarge in length and become reddish or purplish. Later, striae tend to appear as white, depressed bands that are parallel to the lines of skin tension. Striae distensae occur most often in areas that have been subject to distension such as the lower back, buttocks, thighs, breast, abdomen, and shoulders.
Summary
- Also called
- Purplish striae, Striae, Striae atrophicae, Striae cutis distensae
- Body system
- Abnormality of the integument
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page$trait$nameRead the genes linked to Stretch marks, and the rest of your genome, with one test.
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Get my Genome Test36 condition reports read genes linked to this trait
Dante Labs condition reports look at the genes behind groups of inherited conditions, read from one whole-genome test. Each page says which conditions and genes a report covers, how it is read and what it cannot tell you.
- Marfan Like SyndromesReads 8 of these genesFBN1TGFBR1BGNSMAD2SMAD3TGFB2About this report →
- Loeys-Dietz SyndromeReads 6 of these genesTGFBR1SMAD2SMAD3TGFB2TGFB3TGFBR2About this report →
- Carney Complex & Hereditary Adrenal Cushing SyndromeReads 3 of these genesPRKAR1AARMC5PDE11AAbout this report →
- Aortic AneurysmReads 5 of these genesFBN1TGFBR1TGFB2TGFBR2LOXAbout this report →
Show 32 more reports
- Hereditary Arterial CalcificationReads 2 of these genesABCC6ENPP1About this report →
- Pseudohypoparathyroidism & GNAS-Inactivation DisordersReads 2 of these genesPRKAR1AGNASAbout this report →
- Caffey DiseaseReads 1 of these genesCOL1A1About this report →
- CTNNB1 SyndromeReads 1 of these genesCTNNB1About this report →
- Ferguson-Smith Disease (Multiple Self-Healing Squamous Epithelioma)Reads 1 of these genesTGFBR1About this report →
- KDM1A-Related Neurodevelopmental DisorderReads 1 of these genesKDM1AAbout this report →
- Li-Fraumeni SyndromeReads 1 of these genesTP53About this report →
- Radio-Tartaglia SyndromeReads 1 of these genesSPENAbout this report →
- Stankiewicz-Isidor SyndromeReads 1 of these genesPSMD12About this report →
- Ehlers-Danlos SyndromeReads 4 of these genesCOL1A1COL5A1COL5A2TNXBAbout this report →
- Familial Isolated Pituitary Adenoma (FIPA / X-LAG)Reads 1 of these genesAIPAbout this report →
- Fibrodysplasia Ossificans ProgressivaReads 1 of these genesGNASAbout this report →
- Pseudoxanthoma ElasticumReads 1 of these genesABCC6About this report →
- MelanomaReads 1 of these genesCDKN2AAbout this report →
- Intellectual DisabilityReads 6 of these genesATRXCTNNB1DLG4CHD8FBXO11CUL4BAbout this report →
- Inherited Predisposition to Acute Myeloid LeukaemiaReads 1 of these genesTERTAbout this report →
- Familial Glucocorticoid DeficiencyReads 1 of these genesNR3C1About this report →
- Hereditary Rickets (Hypophosphatemic and Vitamin D-Dependent)Reads 1 of these genesENPP1About this report →
- Malignant Endocrine NeoplasmReads 1 of these genesTP53About this report →
- Autism Spectrum DisorderReads 1 of these genesCHD8About this report →
- Familial Pulmonary FibrosisReads 1 of these genesTERTAbout this report →
- Kidney CancerReads 1 of these genesTP53About this report →
- Usher SyndromeReads 1 of these genesCDH23About this report →
- Urinary and Renal System TumourReads 1 of these genesTP53About this report →
- 46,XY Differences of Sex Development and Gonadal DysgenesisReads 1 of these genesATRXAbout this report →
- Noonan SyndromeReads 1 of these genesBRAFAbout this report →
- Dyskeratosis CongenitaReads 1 of these genesTERTAbout this report →
- Hearing Loss and DeafnessReads 2 of these genesCDH23USP48About this report →
- VitreoretinopathyReads 1 of these genesCTNNB1About this report →
- Thyroid CancerReads 1 of these genesGNASAbout this report →
- Osteogenesis ImperfectaReads 1 of these genesCOL1A1About this report →
- Hypertrophic CardiomyopathyReads 1 of these genesBRAFAbout this report →
Read the genes linked to Stretch marks, and the rest of your genome, with one test.
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Get my Genome Test40 genes linked to Stretch marks
Changes in these genes cause rare conditions in which Stretch marks is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| FBN1fibrillin 1 | Always | In 4 conditions |
| PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alpha | Always | In 4 conditions |
| PSMD12proteasome 26S subunit, non-ATPase 12 | Always | In 1 condition |
| TGFBR1transforming growth factor beta receptor 1 | Always | In 2 conditions |
| COL1A1collagen type I alpha 1 chain | Very often (80–99%) | In 1 condition |
| COL5A1collagen type V alpha 1 chain | Very often (80–99%) | In 2 conditions |
| COL5A2collagen type V alpha 2 chain | Very often (80–99%) | In 1 condition |
| ABCC6ATP binding cassette subfamily C member 6 | Often (30–79%) | In 1 condition |
| ARMC5armadillo repeat containing 5 | Often (30–79%) | In 1 condition |
| ATRXATRX chromatin remodeler | Often (30–79%) | In 1 condition |
| BGNbiglycan | Often (30–79%) | In 1 condition |
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Often (30–79%) | In 1 condition |
| CDH23cadherin related 23 | Often (30–79%) | In 1 condition |
| CDKN2Acyclin dependent kinase inhibitor 2A | Often (30–79%) | In 1 condition |
| COPB1coat protein complex I subunit beta 1 | Often (30–79%) | In 1 condition |
| CTNNB1catenin beta 1 | Often (30–79%) | In 1 condition |
| DLG4discs large MAGUK scaffold protein 4 | Often (30–79%) | In 1 condition |
| ENPP1ectonucleotide pyrophosphatase/phosphodiesterase 1 | Often (30–79%) | In 1 condition |
| GNASGNAS complex locus | Often (30–79%) | In 2 conditions |
| IPO8importin 8 | Often (30–79%) | In 1 condition |
| KDM1Alysine demethylase 1A | Often (30–79%) | In 1 condition |
| NR3C1nuclear receptor subfamily 3 group C member 1 | Often (30–79%) | In 1 condition |
| SMAD2SMAD family member 2 | Often (30–79%) | In 2 conditions |
| SMAD3SMAD family member 3 | Often (30–79%) | In 3 conditions |
| TERTtelomerase reverse transcriptase | Often (30–79%) | In 1 condition |
| TGFB2transforming growth factor beta 2 | Often (30–79%) | In 2 conditions |
| TGFB3transforming growth factor beta 3 | Often (30–79%) | In 1 condition |
| TGFBR2transforming growth factor beta receptor 2 | Often (30–79%) | In 2 conditions |
| TP53tumor protein p53 | Often (30–79%) | In 2 conditions |
| USP48ubiquitin specific peptidase 48 | Often (30–79%) | In 1 condition |
| USP8ubiquitin specific peptidase 8 | Often (30–79%) | In 2 conditions |
| ZNRF3zinc and ring finger 3 | Often (30–79%) | In 1 condition |
| CHD8chromodomain helicase DNA binding protein 8 | Sometimes (5–29%) | In 1 condition |
| FBXO11F-box protein 11 | Sometimes (5–29%) | In 1 condition |
| LOXlysyl oxidase | Sometimes (5–29%) | In 1 condition |
| PDE11Aphosphodiesterase 11A | Sometimes (5–29%) | In 2 conditions |
| SPENspen family transcriptional repressor | Sometimes (5–29%) | In 1 condition |
| TNXBtenascin XB | Sometimes (5–29%) | In 1 condition |
| AIPAHR interacting HSP90 co-chaperone | Not recorded | In 1 condition |
| CUL4Bcullin 4B | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.19-9814e911.
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