Trait
Fatty lump
Clinical name: Lipoma
Benign neoplasia derived from lipoblasts or lipocytes of white or brown fat. May be angiomatous or hibernomatous.
Summary
- Also called
- Noncancerous fatty lump
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test20 genes linked to Fatty lump
Changes in these genes cause rare conditions in which Fatty lump is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| MAD1L1mitotic arrest deficient 1 like 1 | Always | In 1 condition |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Always | In 2 conditions |
| PPP2R5Cprotein phosphatase 2 regulatory subunit B'gamma | Always | In 1 condition |
| AKT1AKT serine/threonine kinase 1 | Very often (80–99%) | In 2 conditions |
| PTENphosphatase and tensin homolog | Very often (80–99%) | In 2 conditions |
| MSTO1misato mitochondrial distribution and morphology regulator 1 | Often (30–79%) | In 1 condition |
| COQ6coenzyme Q6, monooxygenase | Sometimes (5–29%) | In 1 condition |
| LZTR1leucine zipper like post translational regulator 1 | Sometimes (5–29%) | In 1 condition |
| NF2NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor | Sometimes (5–29%) | In 1 condition |
| RPL10ribosomal protein L10 | Sometimes (5–29%) | In 1 condition |
| SMARCB1SWI/SNF related BAF chromatin remodeling complex subunit B1 | Sometimes (5–29%) | In 1 condition |
| TAF1TATA-box binding protein associated factor 1 | Sometimes (5–29%) | In 1 condition |
| APCAPC regulator of Wnt signaling pathway | Rarely (1–4%) | In 1 condition |
| CDC73cell division cycle 73 | Rarely (1–4%) | In 2 conditions |
| NF1neurofibromin 1 | Rarely (1–4%) | In 1 condition |
| FGFR1fibroblast growth factor receptor 1 | Not recorded | In 1 condition |
| FUZfuzzy planar cell polarity protein | Not recorded | In 1 condition |
| TBXTT-box transcription factor T | Not recorded | In 1 condition |
| VANGL1VANGL planar cell polarity protein 1 | Not recorded | In 1 condition |
| VANGL2VANGL planar cell polarity protein 2 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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