Trait
Moderate global developmental delay
A moderate delay in the achievement of motor or mental milestones in the domains of development of a child.
Summary
- Also called
- Global developmental delay, moderate
- Body system
- Abnormality of the nervous system
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page$trait$nameRead the genes linked to Moderate global developmental delay, and the rest of your genome, with one test.
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Get my Genome Test20 condition reports read genes linked to this trait
Dante Labs condition reports look at the genes behind groups of inherited conditions, read from one whole-genome test. Each page says which conditions and genes a report covers, how it is read and what it cannot tell you.
- Hereditary Pheochromocytoma and ParagangliomaReads 3 of these genesSDHASDHBSDHDAbout this report →
- Malignant Endocrine NeoplasmReads 2 of these genesSDHASDHBAbout this report →
- Urinary and Renal System TumourReads 2 of these genesSDHASDHBAbout this report →
- Monogenic Precocious PubertyReads 1 of these genesDLK1About this report →
Show 16 more reports
- NeurofibromatosisReads 1 of these genesNF1About this report →
- Heritable Pulmonary Arterial Hypertension (HPAH)Reads 1 of these genesKCNK3About this report →
- Disorders of Glycine & Serine MetabolismReads 1 of these genesPHGDHAbout this report →
- Kidney CancerReads 1 of these genesSDHBAbout this report →
- Leigh SyndromeReads 2 of these genesAIFM1SDHAAbout this report →
- Hereditary Sensory and Autonomic Neuropathies (incl. Familial Dysautonomia)Reads 1 of these genesAIFM1About this report →
- Other Inborn Errors of ImmunityReads 3 of these genesTET2TPP2PGM3About this report →
- Pelizaeus-Merzbacher Disease & Hypomyelinating LeukodystrophiesReads 1 of these genesPLP1About this report →
- Intellectual DisabilityReads 3 of these genesTCP1ADNPKDM5BAbout this report →
- Primary Mitochondrial DiseaseReads 2 of these genesAIFM1TMEM70About this report →
- Epilepsy (Full Panel)Reads 2 of these genesTMEM63BCDKL5About this report →
- Hereditary Spastic ParaplegiaReads 1 of these genesPLP1About this report →
- Charcot-Marie-Tooth DiseaseReads 1 of these genesAIFM1About this report →
- Other Inherited LeukodystrophiesReads 1 of these genesPLP1About this report →
- Hearing Loss and DeafnessReads 1 of these genesAIFM1About this report →
- Congenital Disorders of GlycosylationReads 1 of these genesPGM3About this report →
Read the genes linked to Moderate global developmental delay, and the rest of your genome, with one test.
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Get my Genome Test42 genes linked to Moderate global developmental delay
Changes in these genes cause rare conditions in which Moderate global developmental delay is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ELFN1extracellular leucine rich repeat and fibronectin type III domain containing 1 | Always | In 1 condition |
| IRX5iroquois homeobox 5 | Always | In 1 condition |
| LRRC7leucine rich repeat containing 7 | Always | In 1 condition |
| TCP1t-complex 1 | Always | In 1 condition |
| TET2tet methylcytosine dioxygenase 2 | Always | In 1 condition |
| TMEM63Btransmembrane protein 63B | Always | In 1 condition |
| TRA2Btransformer 2 beta homolog | Always | In 1 condition |
| UGGT1UDP-glucose glycoprotein glucosyltransferase 1 | Always | In 1 condition |
| YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta | Always | In 1 condition |
| AIFM1apoptosis inducing factor mitochondria associated 1 | Very often (80–99%) | In 1 condition |
| TBX4T-box transcription factor 4 | Very often (80–99%) | In 1 condition |
| TMEM70transmembrane protein 70 | Very often (80–99%) | In 1 condition |
| TPP2tripeptidyl peptidase 2 | Very often (80–99%) | In 1 condition |
| ADNPactivity dependent neuroprotector homeobox | Often (30–79%) | In 1 condition |
| CDKL5cyclin dependent kinase like 5 | Often (30–79%) | In 1 condition |
| DHRS3dehydrogenase/reductase 3 | Often (30–79%) | In 1 condition |
| HSD17B10hydroxysteroid 17-beta dehydrogenase 10 | Often (30–79%) | In 1 condition |
| KDM2Blysine demethylase 2B | Often (30–79%) | In 1 condition |
| KDM5Blysine demethylase 5B | Often (30–79%) | In 1 condition |
| MAB21L1mab-21 like 1 | Often (30–79%) | In 1 condition |
| NCAPD3non-SMC condensin II complex subunit D3 | Often (30–79%) | In 1 condition |
| NF1neurofibromin 1 | Often (30–79%) | In 1 condition |
| PGM3phosphoglucomutase 3 | Often (30–79%) | In 1 condition |
| PPP2R5Cprotein phosphatase 2 regulatory subunit B'gamma | Often (30–79%) | In 1 condition |
| PSMC3proteasome 26S subunit, ATPase 3 | Often (30–79%) | In 1 condition |
| RPS6KC1ribosomal protein S6 kinase C1 | Often (30–79%) | In 1 condition |
| TANGO2transport and golgi organization 2 homolog | Often (30–79%) | In 1 condition |
| DLK1delta like non-canonical Notch ligand 1 | Sometimes (5–29%) | In 1 condition |
| KCNK3potassium two pore domain channel subfamily K member 3 | Sometimes (5–29%) | In 1 condition |
| MADDMAP kinase activating death domain | Sometimes (5–29%) | In 1 condition |
| MEG3maternally expressed 3 | Sometimes (5–29%) | In 1 condition |
| PHGDHphosphoglycerate dehydrogenase | Sometimes (5–29%) | In 1 condition |
| PLP1proteolipid protein 1 | Sometimes (5–29%) | In 1 condition |
| RNU4-2RNA, U4 small nuclear 2 | Sometimes (5–29%) | In 1 condition |
| RNU5B-1RNA, U5B small nuclear 1 | Sometimes (5–29%) | In 1 condition |
| RTL1retrotransposon Gag like 1 | Sometimes (5–29%) | In 1 condition |
| SDHAsuccinate dehydrogenase complex flavoprotein subunit A | Sometimes (5–29%) | In 1 condition |
| SDHAF1succinate dehydrogenase complex assembly factor 1 | Sometimes (5–29%) | In 1 condition |
| SDHBsuccinate dehydrogenase complex iron sulfur subunit B | Sometimes (5–29%) | In 1 condition |
| SDHDsuccinate dehydrogenase complex subunit D | Sometimes (5–29%) | In 1 condition |
Show 2 more genes
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.17-8666dff2.
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