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Trait
Mole
Clinical name: Nevus
A nevus is a type of hamartoma that is a circumscribed stable malformation of the skin.
Summary
- Also called
- Naevus
- Body system
- Abnormality of the integument
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This page as data
Add .json to the page's address, or ask for application/json, to read it as JSON.
library(jsonlite)
url <- "https://dantelabs.com/traits/nevus.json"
page <- fromJSON(url)
page$trait$nameMoleHP:0003764
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Get my Genome Test39 condition reports read genes linked to this trait
Dante Labs condition reports look at the genes behind groups of inherited conditions, read from one whole-genome test. Each page says which conditions and genes a report covers, how it is read and what it cannot tell you.
- MelanomaReads 4 of these genesCDK4CDKN2AMITFPOT1About this report →
- Cowden Syndrome (PTEN hamartoma tumour syndrome)Reads 2 of these genesPTENAKT1About this report →
- Noonan SyndromeReads 6 of these genesBRAFNRASRAF1LZTR1HRASKRASAbout this report →
- BAP1 Tumour Predisposition SyndromeReads 1 of these genesBAP1About this report →
Show 35 more reports
- Lamb-Shaffer SyndromeReads 1 of these genesSOX5About this report →
- Mowat-Wilson SyndromeReads 1 of these genesZEB2About this report →
- Hypertrophic CardiomyopathyReads 6 of these genesBRAFNRASRAF1LZTR1HRASKRASAbout this report →
- Neuroblastoma Predisposition (ALK and PHOX2B)Reads 1 of these genesALKAbout this report →
- Nevoid Basal Cell Carcinoma (Gorlin) SyndromeReads 1 of these genesSUFUAbout this report →
- Epidermolysis BullosaReads 3 of these genesCOL7A1KRT14KRT5About this report →
- Familial Pulmonary FibrosisReads 2 of these genesPOT1TERTAbout this report →
- Dyskeratosis CongenitaReads 3 of these genesACDPOT1TERTAbout this report →
- MedulloblastomaReads 1 of these genesSUFUAbout this report →
- Carney Complex & Hereditary Adrenal Cushing SyndromeReads 1 of these genesPRKAR1AAbout this report →
- NeurofibromatosisReads 1 of these genesLZTR1About this report →
- Pseudohypoparathyroidism & GNAS-Inactivation DisordersReads 1 of these genesPRKAR1AAbout this report →
- Ectodermal DysplasiasReads 2 of these genesKRT14TP63About this report →
- Autoimmune DiseaseReads 2 of these genesCHRNGKRASAbout this report →
- Cornelia de Lange SyndromeReads 1 of these genesHDAC8About this report →
- Autoimmune Lymphoproliferative Syndrome (ALPS)Reads 1 of these genesKRASAbout this report →
- Hyper-IgE SyndromeReads 1 of these genesSPINK5About this report →
- Waardenburg SyndromeReads 1 of these genesMITFAbout this report →
- Oculocutaneous AlbinismReads 1 of these genesSLC45A2About this report →
- Inherited ThrombocytopeniasReads 2 of these genesCDC42ACTBAbout this report →
- Kidney CancerReads 1 of these genesBAP1About this report →
- Urinary and Renal System TumourReads 1 of these genesBAP1About this report →
- Diamond-Blackfan AnemiaReads 1 of these genesHEATR3About this report →
- Fanconi AnemiaReads 1 of these genesRAD51About this report →
- Inherited IchthyosesReads 1 of these genesNSDHLAbout this report →
- Intellectual DisabilityReads 3 of these genesZEB2NSDHLH1-4About this report →
- Hereditary Palmoplantar Keratodermas and Pachyonychia CongenitaReads 1 of these genesKRT14About this report →
- Dystonia, Myotonia, Paroxysmal DyskinesiaReads 1 of these genesACTBAbout this report →
- Joubert Syndrome And Related DisordersReads 1 of these genesSUFUAbout this report →
- DNA Repair DiseaseReads 1 of these genesRAD51About this report →
- Dilated CardiomyopathyReads 1 of these genesRAF1About this report →
- Female InfertilityReads 1 of these genesTP63About this report →
- Other Inborn Errors of ImmunityReads 2 of these genesSPINK5KRASAbout this report →
- Congenital Disorders of GlycosylationReads 1 of these genesKRT5About this report →
- Epilepsy (Full Panel)Reads 1 of these genesZEB2About this report →
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Get my Genome Test51 genes linked to Mole
Changes in these genes cause rare conditions in which Mole is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| LEMD3LEM domain containing 3 | Always | In 1 condition |
| MAD1L1mitotic arrest deficient 1 like 1 | Always | In 1 condition |
| POLR1ARNA polymerase I subunit A | Always | In 1 condition |
| RAD51RAD51 recombinase | Always | In 1 condition |
| SPINK5serine peptidase inhibitor Kazal type 5 | Always | In 1 condition |
| ACDACD shelterin complex subunit and telomerase recruitment factor | Very often (80–99%) | In 1 condition |
| ALKALK receptor tyrosine kinase | Very often (80–99%) | In 1 condition |
| BAP1BRCA1 associated deubiquitinase 1 | Very often (80–99%) | In 1 condition |
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Very often (80–99%) | In 1 condition |
| CDK4cyclin dependent kinase 4 | Very often (80–99%) | In 1 condition |
| CDKN2Acyclin dependent kinase inhibitor 2A | Very often (80–99%) | In 1 condition |
| CDKN2Bcyclin dependent kinase inhibitor 2B | Very often (80–99%) | In 1 condition |
| MC1Rmelanocortin 1 receptor | Very often (80–99%) | In 1 condition |
| MGMTO-6-methylguanine-DNA methyltransferase | Very often (80–99%) | In 1 condition |
| MITFmelanocyte inducing transcription factor | Very often (80–99%) | In 1 condition |
| NRASNRAS proto-oncogene, GTPase | Very often (80–99%) | In 2 conditions |
| POT1protection of telomeres 1 | Very often (80–99%) | In 1 condition |
| PTENphosphatase and tensin homolog | Very often (80–99%) | In 1 condition |
| RAF1Raf-1 proto-oncogene, serine/threonine kinase | Very often (80–99%) | In 2 conditions |
| SOX5SRY-box transcription factor 5 | Very often (80–99%) | In 1 condition |
| TERF2IPTERF2 interacting protein | Very often (80–99%) | In 1 condition |
| TERTtelomerase reverse transcriptase | Very often (80–99%) | In 1 condition |
| ZEB2zinc finger E-box binding homeobox 2 | Very often (80–99%) | In 1 condition |
| ALX4ALX homeobox 4 | Often (30–79%) | In 1 condition |
| CDH11cadherin 11 | Often (30–79%) | In 1 condition |
| CYP26C1cytochrome P450 family 26 subfamily C member 1 | Often (30–79%) | In 1 condition |
| DUTdeoxyuridine triphosphatase | Often (30–79%) | In 1 condition |
| HEATR3HEAT repeat containing 3 | Often (30–79%) | In 1 condition |
| NSDHLNAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL | Often (30–79%) | In 1 condition |
| SUFUSUFU negative regulator of hedgehog signaling | Often (30–79%) | In 1 condition |
| CDC42cell division cycle 42 | Sometimes (5–29%) | In 2 conditions |
| CHRNGcholinergic receptor nicotinic gamma subunit | Sometimes (5–29%) | In 1 condition |
| COL7A1collagen type VII alpha 1 chain | Sometimes (5–29%) | In 1 condition |
| H1-4H1.4 linker histone, cluster member | Sometimes (5–29%) | In 1 condition |
| H4C5H4 clustered histone 5 | Sometimes (5–29%) | In 1 condition |
| KRT14keratin 14 | Sometimes (5–29%) | In 1 condition |
| KRT5keratin 5 | Sometimes (5–29%) | In 1 condition |
| LZTR1leucine zipper like post translational regulator 1 | Sometimes (5–29%) | In 1 condition |
| MSL3MSL complex subunit 3 | Sometimes (5–29%) | In 1 condition |
| MYH3myosin heavy chain 3 | Sometimes (5–29%) | In 1 condition |
Show 11 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Sometimes (5–29%) | In 1 condition |
| TP63tumor protein p63 | Sometimes (5–29%) | In 1 condition |
| PPP2R5Cprotein phosphatase 2 regulatory subunit B'gamma | Rarely (1–4%) | In 1 condition |
| SLC45A2solute carrier family 45 member 2 | Rarely (1–4%) | In 1 condition |
| SPTBN1spectrin beta, non-erythrocytic 1 | Rarely (1–4%) | In 1 condition |
| ACTBactin beta | Not recorded | In 1 condition |
| AKT1AKT serine/threonine kinase 1 | Not recorded | In 1 condition |
| HDAC8histone deacetylase 8 | Not recorded | In 1 condition |
| HRASHRas proto-oncogene, GTPase | Not recorded | In 2 conditions |
| KRASKRas proto-oncogene, GTPase | Not recorded | In 1 condition |
| PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alpha | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.18-e609d43e.
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