Trait
Decreased number of teeth
Clinical name: Tooth agenesis
The absence of one or more teeth from the normal series by a failure to develop
Summary
- Also called
- Decreased tooth count, Fewer teeth than normal, Missing some teeth, Reduced number of teeth, Dental agenesis, Failure of development of some teeth, Teeth, agenesis
- Body system
- Abnormality of head or neck
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test74 genes linked to Decreased number of teeth
Changes in these genes cause rare conditions in which Decreased number of teeth is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| CREB3L1cAMP responsive element binding protein 3 like 1 | Always | In 1 condition |
| CTNND1catenin delta 1 | Always | In 1 condition |
| DSPdesmoplakin | Always | In 2 conditions |
| ADAMTS3ADAM metallopeptidase with thrombospondin type 1 motif 3 | Very often (80–99%) | In 1 condition |
| CCBE1collagen and calcium binding EGF domains 1 | Very often (80–99%) | In 1 condition |
| CTSCcathepsin C | Very often (80–99%) | In 1 condition |
| DPP6dipeptidyl peptidase like 6 | Very often (80–99%) | In 1 condition |
| FAT4FAT atypical cadherin 4 | Very often (80–99%) | In 1 condition |
| FGFR1fibroblast growth factor receptor 1 | Very often (80–99%) | In 3 conditions |
| FGFR2fibroblast growth factor receptor 2 | Very often (80–99%) | In 1 condition |
| GHRgrowth hormone receptor | Very often (80–99%) | In 1 condition |
| GJA1gap junction protein alpha 1 | Very often (80–99%) | In 1 condition |
| LMNB1lamin B1 | Very often (80–99%) | In 1 condition |
| PCNTpericentrin | Very often (80–99%) | In 2 conditions |
| SLC25A24solute carrier family 25 member 24 | Very often (80–99%) | In 1 condition |
| TP63tumor protein p63 | Very often (80–99%) | In 1 condition |
| VPS13Bvacuolar protein sorting 13 homolog B | Very often (80–99%) | In 1 condition |
| ATRATR checkpoint kinase | Often (30–79%) | In 1 condition |
| ATRIPATR interacting protein | Often (30–79%) | In 1 condition |
| CENPEcentromere protein E | Often (30–79%) | In 1 condition |
| CEP152centrosomal protein 152 | Often (30–79%) | In 1 condition |
| CEP295centrosomal protein 295 | Often (30–79%) | In 1 condition |
| CEP63centrosomal protein 63 | Often (30–79%) | In 1 condition |
| CPAPcentrosome assembly and centriole elongation protein | Often (30–79%) | In 1 condition |
| DNA2DNA replication helicase/nuclease 2 | Often (30–79%) | In 1 condition |
| NINninein | Often (30–79%) | In 1 condition |
| NSMCE2NSE2 SUMO ligase component of SMC5/6 complex | Often (30–79%) | In 1 condition |
| NUP85nucleoporin 85 | Often (30–79%) | In 1 condition |
| PLK4polo like kinase 4 | Often (30–79%) | In 1 condition |
| POLR1BRNA polymerase I subunit B | Often (30–79%) | In 1 condition |
| POLR1CRNA polymerase I and III subunit C | Often (30–79%) | In 1 condition |
| POLR1DRNA polymerase I and III subunit D | Often (30–79%) | In 1 condition |
| PORCNporcupine O-acyltransferase | Often (30–79%) | In 1 condition |
| RBBP8RB binding protein 8, endonuclease | Often (30–79%) | In 1 condition |
| ROR2ROR family WNT receptor 2 | Often (30–79%) | In 1 condition |
| TCOF1treacle ribosome biogenesis factor 1 | Often (30–79%) | In 1 condition |
| TFAP2Atranscription factor AP-2 alpha | Often (30–79%) | In 1 condition |
| TRAIPTRAF interacting protein | Often (30–79%) | In 1 condition |
| AKT1AKT serine/threonine kinase 1 | Sometimes (5–29%) | In 1 condition |
| ALMS1ALMS1 centrosome and basal body associated protein | Sometimes (5–29%) | In 1 condition |
Show 34 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| ANAPC1anaphase promoting complex subunit 1 | Sometimes (5–29%) | In 1 condition |
| ANOS1anosmin 1 | Sometimes (5–29%) | In 1 condition |
| CCDC141coiled-coil domain containing 141 | Sometimes (5–29%) | In 1 condition |
| CHD7chromodomain helicase DNA binding protein 7 | Sometimes (5–29%) | In 1 condition |
| COL9A2collagen type IX alpha 2 chain | Sometimes (5–29%) | In 1 condition |
| DCCDCC netrin 1 receptor | Sometimes (5–29%) | In 1 condition |
| DHCR77-dehydrocholesterol reductase | Sometimes (5–29%) | In 1 condition |
| DHX37DEAH-box helicase 37 | Sometimes (5–29%) | In 1 condition |
| DUSP6dual specificity phosphatase 6 | Sometimes (5–29%) | In 1 condition |
| EMX2empty spiracles homeobox 2 | Sometimes (5–29%) | In 1 condition |
| FAM20AFAM20A golgi associated secretory pathway pseudokinase | Sometimes (5–29%) | In 1 condition |
| FEZF1FEZ family zinc finger 1 | Sometimes (5–29%) | In 1 condition |
| FGF17fibroblast growth factor 17 | Sometimes (5–29%) | In 1 condition |
| FGF8fibroblast growth factor 8 | Sometimes (5–29%) | In 1 condition |
| FLRT3fibronectin leucine rich transmembrane protein 3 | Sometimes (5–29%) | In 1 condition |
| HESX1HESX homeobox 1 | Sometimes (5–29%) | In 1 condition |
| HNRNPKheterogeneous nuclear ribonucleoprotein K | Sometimes (5–29%) | In 2 conditions |
| HS6ST1heparan sulfate 6-O-sulfotransferase 1 | Sometimes (5–29%) | In 1 condition |
| IL17RDinterleukin 17 receptor D | Sometimes (5–29%) | In 1 condition |
| NDNFneuron derived neurotrophic factor | Sometimes (5–29%) | In 1 condition |
| OCRLOCRL inositol polyphosphate-5-phosphatase | Sometimes (5–29%) | In 1 condition |
| PLXND1plexin D1 | Sometimes (5–29%) | In 1 condition |
| PROK2prokineticin 2 | Sometimes (5–29%) | In 1 condition |
| PROKR2prokineticin receptor 2 | Sometimes (5–29%) | In 1 condition |
| RECQL4RecQ like helicase 4 | Sometimes (5–29%) | In 1 condition |
| REV3LREV3 like, DNA directed polymerase zeta catalytic subunit | Sometimes (5–29%) | In 1 condition |
| SEMA3Asemaphorin 3A | Sometimes (5–29%) | In 1 condition |
| SOX10SRY-box transcription factor 10 | Sometimes (5–29%) | In 1 condition |
| SPRY4sprouty RTK signaling antagonist 4 | Sometimes (5–29%) | In 1 condition |
| TACR3tachykinin receptor 3 | Sometimes (5–29%) | In 1 condition |
| WDR11WD repeat domain 11 | Sometimes (5–29%) | In 1 condition |
| SLC10A7solute carrier family 10 member 7 | Rarely (1–4%) | In 1 condition |
| EDAectodysplasin A | Not recorded | In 1 condition |
| WNT10AWnt family member 10A | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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