Skip to content
Use your HSA or FSA funds

Gene

FEZF1

FEZ family zinc finger 1

Summary

Cytogenetic location
7q31.32
Coordinates
Chromosome 7: 122,301,303–122,304,750 (GRCh38)
Exons
4 exons across 3.4 kb
Protein
475 amino acids
Previous symbols
ZNF312B
MANE Select transcript
ENST00000442488.7NM_001024613.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

  • Hypogonadotropic Hypogonadism

    • Abnormal ovarian or testicular function due to insufficient hormonal stimulation from the hypothalamic-pituitary axis.

      • 2 GenCC submitters rate it definitive or strong

How FEZF1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 7, with a bracket where FEZF1 sits. FEZF1 and 5 genes near it on chromosome 7, from 121,803,027 to 122,803,026.Chromosome 77q31.32p22.3p22.2p22.1p21.3p21.2p21.1p15.3p15.2p15.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.21q11.22q11.23q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q31.1q31.2q31.31q31.32q31.33q32.1q32.2q32.3q33q34q35q36.1q36.2q36.3122 Mb122.2 Mb122.4 Mb122.6 Mb122.8 MbPTPRZ1: 121,873,089–122,062,037, forward strandPTPRZ1AASS: 122,064,583–122,144,489, reverse strandAASSFEZF1: 122,301,303–122,304,750, reverse strandFEZF1CADPS2: 122,318,258–122,886,779, reverse strandCADPS2RNF133: 122,697,735–122,699,117, reverse strandRNF133RNF148: 122,701,668–122,702,922, reverse strandRNF148Diagram of FEZF1: 4 exons on the reverse strand of chromosome 7Exon 4: 122,301,303–122,302,355, 1,053 basesExon 3: 122,302,799–122,302,931, 133 basesExon 2: 122,303,177–122,303,311, 135 basesExon 1: 122,303,637–122,304,750, 1,114 bases43215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.4 kb of the gene's 3.4 kb; 1,428 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). FEZF1 gene: FEZ family zinc finger 1. Retrieved 16 October 2026, from https://dantelabs.com/genes/fezf1

Vancouver

Dante Labs. FEZF1 gene: FEZ family zinc finger 1 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/fezf1

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test