Trait
Failure of development of all teeth
Clinical name: Anodontia
The absence of all teeth from the normal series by a failure to develop.
Summary
- Also called
- Missing all teeth, Total absence of all teeth, Anodontia vera, Complete agenesis of all teeth, Complete dental agenesis
- Body system
- Abnormality of head or neck
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test19 genes linked to Failure of development of all teeth
Changes in these genes cause rare conditions in which Failure of development of all teeth is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| PIGAphosphatidylinositol glycan anchor biosynthesis class A | Always | In 1 condition |
| FLNAfilamin A | Very often (80–99%) | In 2 conditions |
| DCAF17DDB1 and CUL4 associated factor 17 | Sometimes (5–29%) | In 2 conditions |
| DVL1dishevelled segment polarity protein 1 | Sometimes (5–29%) | In 1 condition |
| DVL3dishevelled segment polarity protein 3 | Sometimes (5–29%) | In 1 condition |
| ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit | Sometimes (5–29%) | In 1 condition |
| ERCC4ERCC excision repair 4, endonuclease catalytic subunit | Sometimes (5–29%) | In 1 condition |
| ERCC6ERCC excision repair 6, chromatin remodeling factor | Sometimes (5–29%) | In 2 conditions |
| ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit | Sometimes (5–29%) | In 2 conditions |
| FZD2frizzled class receptor 2 | Sometimes (5–29%) | In 1 condition |
| GBA1glucosylceramidase beta 1 | Sometimes (5–29%) | In 1 condition |
| NECTIN1nectin cell adhesion molecule 1 | Sometimes (5–29%) | In 2 conditions |
| RPS6KA3ribosomal protein S6 kinase A3 | Sometimes (5–29%) | In 1 condition |
| WNT5AWnt family member 5A | Sometimes (5–29%) | In 1 condition |
| GRHL3grainyhead like transcription factor 3 | Rarely (1–4%) | In 1 condition |
| EDAectodysplasin A | Not recorded | In 1 condition |
| EDARectodysplasin A receptor | Not recorded | In 2 conditions |
| EDARADDEDAR associated via death domain | Not recorded | In 2 conditions |
| IFT122intraflagellar transport 122 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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