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Gene

DCC

DCC netrin 1 receptor

Summary

Cytogenetic location
18q21.2
Coordinates
Chromosome 18: 52,340,197–53,535,899 (GRCh38)
Exons
29 exons across 1,195.7 kb
Protein
1,447 amino acids
Also known as
IGDCC1, NTN1R1
MANE Select transcript
ENST00000442544.7NM_005215.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads DCC yet. The test sequences your whole genome, so your data includes it all the same.

How DCC is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 18, with a bracket where DCC sits. DCC and 7 genes near it on chromosome 18, from 51,144,494 to 54,731,602.Chromosome 1818q21.2p11.32p11.31p11.23p11.22p11.21p11.1q11.1q11.2q12.1q12.2q12.3q21.1q21.2q21.31q21.32q21.33q22.1q22.2q22.3q2351.5 Mb52 Mb52.5 Mb53 Mb53.5 Mb54 Mb54.5 MbMEX3C: 51,174,550–51,218,333, reverse strandMEX3CDCC: 52,340,197–53,535,899, forward strandDCCMBD2: 54,151,606–54,224,787, reverse strandMBD2POLI: 54,269,483–54,321,266, forward strandPOLISTARD6: 54,324,358–54,357,964, reverse strandSTARD6C18orf54: 54,357,900–54,385,218, forward strandC18orf54DYNAP: 54,587,757–54,599,888, forward strandDYNAPRAB27B: 54,717,857–54,895,516, forward strandRAB27BDiagram of DCC: 29 exons on the forward strand of chromosome 18Exon 2: 1 known disease-causing siteExon 4: 1 known disease-causing siteExon 7: 2 known disease-causing sitesExon 9: 1 known disease-causing siteExon 13: 2 known disease-causing sitesExon 15: 4 known disease-causing sitesExon 16: 1 known disease-causing siteExon 17: 2 known disease-causing sitesExon 18: 1 known disease-causing siteExon 20: 1 known disease-causing siteExon 24: 1 known disease-causing siteExon 26: 1 known disease-causing siteExon 27: 1 known disease-causing siteExon 1: 52,340,197–52,340,878, 682 basesExon 2: 52,752,054–52,752,374, 321 basesExon 3: 52,906,044–52,906,328, 285 basesExon 4: 52,923,707–52,923,857, 151 basesExon 5: 52,925,234–52,925,370, 137 basesExon 6: 53,063,305–53,063,459, 155 basesExon 7: 53,066,046–53,066,166, 121 basesExon 8: 53,157,356–53,157,512, 157 basesExon 9: 53,178,962–53,179,116, 155 basesExon 10: 53,205,216–53,205,364, 149 basesExon 11: 53,207,679–53,207,817, 139 basesExon 12: 53,215,548–53,215,597, 50 basesExon 13: 53,305,578–53,305,719, 142 basesExon 14: 53,322,047–53,322,157, 111 basesExon 15: 53,339,713–53,339,907, 195 basesExon 16: 53,386,043–53,386,138, 96 basesExon 17: 53,391,655–53,391,887, 233 basesExon 18: 53,397,308–53,397,446, 139 basesExon 19: 53,402,786–53,402,893, 108 basesExon 20: 53,410,452–53,410,646, 195 basesExon 21: 53,416,124–53,416,156, 33 basesExon 22: 53,435,144–53,435,209, 66 basesExon 23: 53,450,500–53,450,662, 163 basesExon 24: 53,459,232–53,459,458, 227 basesExon 25: 53,467,894–53,468,010, 117 basesExon 26: 53,486,797–53,486,958, 162 basesExon 27: 53,499,298–53,499,510, 213 basesExon 28: 53,526,617–53,526,759, 143 basesExon 29: 53,530,564–53,535,899, 5,336 bases1510152025295′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 10.2 kb of the gene's 1,195.7 kb; 4,344 of those bases code for the protein.

How a genome test reads DCC

21

positions in DCC where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 1,195.7 kb of DCC, introns included, not only the 10.2 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). DCC gene: DCC netrin 1 receptor. Retrieved 17 October 2026, from https://dantelabs.com/genes/dcc

Vancouver

Dante Labs. DCC gene: DCC netrin 1 receptor [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/dcc

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