Gene
EMX2
empty spiracles homeobox 2
- HGNC 3341↗(opens in a new tab)
- Ensembl gene ENSG00000170370↗(opens in a new tab)
- NCBI Gene 2018↗(opens in a new tab)
Summary
- Cytogenetic location
- 10q26.11
- Coordinates
- Chromosome 10: 117,542,746–117,549,546 (GRCh38)
- Exons
- 3 exons across 6.8 kb
- Protein
- 252 amino acids
- MANE Select transcript
- ENST00000553456.5NM_004098.4
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How EMX2 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 2.6 kb of the gene's 6.8 kb; 759 of those bases code for the protein.
Traits linked to EMX2
The Human Phenotype Ontology lists these as features of the rare conditions EMX2 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the musculoskeletal system
- Delayed bone maturation
- Low solidness and mass of the bones
- Osteopenia
- Osteoporosis
- Abnormal skeletal development
- Hypermobility of all joints
- Low muscle tone
- Muscle weakness
Show 2 more traits
Abnormality of the endocrine system
- Absence of pubertal development
- Absence of secondary sex characteristics
- Anterior hypopituitarism
- Decreased function of male gonad
- Decreased serum testosterone level
- Delayed puberty
- Female hypogonadism
- Gonadotropin-releasing hormone deficiency
Show 1 more trait
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). EMX2 gene: empty spiracles homeobox 2. Retrieved 16 October 2026, from https://dantelabs.com/genes/emx2
Dante Labs. EMX2 gene: empty spiracles homeobox 2 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/emx2
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