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Gene

NHLH2

nescient helix-loop-helix 2

Summary

Cytogenetic location
1p13.1
Coordinates
Chromosome 1: 115,836,377–115,841,126 (GRCh38)
Exons
3 exons across 4.8 kb
Protein
135 amino acids
Also known as
NSCL2, bHLHa34
Previous symbols
HEN2
MANE Select transcript
ENST00000320238.3NM_005599.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads NHLH2 yet. The test sequences your whole genome, so your data includes it all the same.

How NHLH2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 1, with a bracket where NHLH2 sits. NHLH2 and 5 genes near it on chromosome 1, from 115,338,752 to 116,338,751.Chromosome 11p13.1p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q44115.4 Mb115.6 Mb115.8 Mb116 Mb116.2 MbNGF: 115,285,904–115,338,770, reverse strandNGFVANGL1: 115,641,854–115,698,224, forward strandVANGL1CASQ2: 115,697,988–115,837,921, reverse strandCASQ2NHLH2: 115,836,377–115,841,126, reverse strandNHLH2SLC22A15: 115,976,310–116,072,747, forward strandSLC22A15MAB21L3: 116,111,068–116,138,149, forward strandMAB21L3Diagram of NHLH2: 3 exons on the reverse strand of chromosome 1Exon 3: 115,836,377–115,838,380, 2,004 basesExon 2: 115,840,216–115,840,544, 329 basesExon 1: 115,840,948–115,841,126, 179 bases3215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.5 kb of the gene's 4.8 kb; 408 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). NHLH2 gene: nescient helix-loop-helix 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/nhlh2

Vancouver

Dante Labs. NHLH2 gene: nescient helix-loop-helix 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/nhlh2

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