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Gene

KISS1

KiSS-1 metastasis suppressor

Summary

Cytogenetic location
1q32.1
Coordinates
Chromosome 1: 204,190,341–204,196,491 (GRCh38)
Exons
3 exons across 6.2 kb
Protein
138 amino acids
MANE Select transcript
ENST00000367194.5NM_002256.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads KISS1 yet. The test sequences your whole genome, so your data includes it all the same.

How KISS1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
Chromosome 1, with a bracket where KISS1 sits. KISS1 and 15 genes near it on chromosome 1, from 203,693,416 to 204,693,415.Chromosome 11q32.1p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q44203.8 Mb204 Mb204.2 Mb204.4 Mb204.6 MbATP2B4: 203,626,664–203,744,081, forward strandATP2B4LAX1: 203,765,169–203,778,175, forward strandLAX1ZC3H11A: 203,795,562–203,854,999, forward strandZC3H11AZBED6: 203,795,623–203,854,999, forward strandZBED6: 203,802,094–203,802,192, forward strandSNRPE: 203,861,496–203,871,152, forward strandSNRPESOX13: 204,073,106–204,127,744, forward strandSOX13ETNK2: 204,131,062–204,152,184, reverse strandETNK2REN: 204,154,815–204,190,324, reverse strandRENKISS1: 204,190,341–204,196,491, reverse strandKISS1GOLT1A: 204,198,157–204,214,121, reverse strandGOLT1APLEKHA6: 204,218,851–204,378,391, reverse strandPLEKHA6PPP1R15B: 204,396,492–204,411,887, reverse strandPPP1R15BPIK3C2B: 204,421,803–204,494,858, reverse strandPIK3C2BMDM4: 204,516,369–204,558,120, forward strandMDM4LRRN2: 204,617,170–204,685,745, reverse strandLRRN2Diagram of KISS1: 3 exons on the reverse strand of chromosome 1Exon 3: 1 known disease-causing siteExon 3: 204,190,341–204,190,797, 457 basesExon 2: 204,192,774–204,192,914, 141 basesExon 1: 204,196,376–204,196,491, 116 bases3215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 0.7 kb of the gene's 6.2 kb; 417 of those bases code for the protein.

How a genome test reads KISS1

1

position in KISS1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 6.2 kb of KISS1, introns included, not only the 0.7 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). KISS1 gene: KiSS-1 metastasis suppressor. Retrieved 17 October 2026, from https://dantelabs.com/genes/kiss1

Vancouver

Dante Labs. KISS1 gene: KiSS-1 metastasis suppressor [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/kiss1

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