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Gene

YY1

YY1 transcription factor

Summary

Cytogenetic location
14q32.2
Coordinates
Chromosome 14: 100,239,144–100,282,788 (GRCh38)
Exons
5 exons across 43.6 kb
Protein
414 amino acids
Also known as
NF-E1, DELTA, UCRBP, YIN-YANG-1, INO80S
MANE Select transcript
ENST00000262238.10NM_003403.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads YY1 yet. The test sequences your whole genome, so your data includes it all the same.

How YY1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 14, with a bracket where YY1 sits. YY1 and 9 genes near it on chromosome 14, from 99,760,966 to 100,760,965.Chromosome 1414q32.2p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.11q32.12q32.13q32.2q32.31q32.32q32.3399.8 Mb100 Mb100.2 Mb100.4 Mb100.6 MbEML1: 99,737,693–99,942,060, forward strandEML1EVL: 99,971,444–100,144,236, forward strandEVLDEGS2: 100,143,957–100,159,688, reverse strandDEGS2YY1: 100,239,144–100,282,788, forward strandYY1SLC25A29: 100,291,116–100,306,547, reverse strandSLC25A29SLC25A47: 100,323,156–100,330,421, forward strandSLC25A47WARS1: 100,333,782–100,376,805, reverse strandWARS1WDR25: 100,376,418–100,530,306, forward strandWDR25BEGAIN: 100,537,147–100,587,430, reverse strandBEGAINDLK1: 100,725,705–100,738,224, forward strandDLK1Diagram of YY1: 5 exons on the forward strand of chromosome 14Exon 1: 2 known disease-causing sitesExon 2: 1 known disease-causing siteExon 4: 5 known disease-causing sitesExon 5: 8 known disease-causing sitesExon 1: 100,239,144–100,239,923, 780 basesExon 2: 100,262,304–100,262,466, 163 basesExon 3: 100,274,698–100,274,758, 61 basesExon 4: 100,276,490–100,276,648, 159 basesExon 5: 100,277,418–100,282,788, 5,371 bases123455′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 6.5 kb of the gene's 43.6 kb; 1,245 of those bases code for the protein.

How a genome test reads YY1

18

positions in YY1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 43.6 kb of YY1, introns included, not only the 6.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). YY1 gene: YY1 transcription factor. Retrieved 16 October 2026, from https://dantelabs.com/genes/yy1

Vancouver

Dante Labs. YY1 gene: YY1 transcription factor [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/yy1

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