Trait
Primary hyperparathyroidism
A type of hyperparathyroidism caused by a primary abnormality of the parathyroid glands (e.g., adenoma, carcinoma, hyperplasia). Primary hyperparathyroidism is associated with hyercalcemia.
Summary
- Body system
- Abnormality of the endocrine system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Primary hyperparathyroidism, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test12 genes linked to Primary hyperparathyroidism
Changes in these genes cause rare conditions in which Primary hyperparathyroidism is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| CDC73cell division cycle 73 | Always | In 4 conditions |
| CDKN1Bcyclin dependent kinase inhibitor 1B | Always | In 2 conditions |
| GCM2GCM transcription factor 2 | Always | In 2 conditions |
| CDKN2Bcyclin dependent kinase inhibitor 2B | Very often (80–99%) | In 1 condition |
| MEN1menin 1 | Very often (80–99%) | In 4 conditions |
| YY1YY1 transcription factor | Often (30–79%) | In 1 condition |
| ARMC5armadillo repeat containing 5 | Rarely (1–4%) | In 1 condition |
| GNASGNAS complex locus | Rarely (1–4%) | In 1 condition |
| KDM1Alysine demethylase 1A | Rarely (1–4%) | In 1 condition |
| AP2S1adaptor related protein complex 2 subunit sigma 1 | Not recorded | In 1 condition |
| CASRcalcium sensing receptor | Not recorded | In 1 condition |
| GNA11G protein subunit alpha 11 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks