Trait
Gliosis
Gliosis is the focal proliferation of glial cells in the central nervous system.
Summary
- Also called
- Cerebral gliosis, Excess astrocytes in brain
- Body system
- Abnormality of the nervous system
Reference genomeGRCh38hg38
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Get my Genome Test91 genes linked to Gliosis
Changes in these genes cause rare conditions in which Gliosis is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ATP6V1AATPase H+ transporting V1 subunit A | Always | In 1 condition |
| DNM1Ldynamin 1L | Always | In 1 condition |
| EIF4A2eukaryotic translation initiation factor 4A2 | Always | In 1 condition |
| ERCC6ERCC excision repair 6, chromatin remodeling factor | Always | In 1 condition |
| ESAMendothelial cell adhesion molecule | Always | In 1 condition |
| GDAP2ganglioside induced differentiation associated protein 2 | Always | In 1 condition |
| MAN2B2mannosidase alpha class 2B member 2 | Always | In 1 condition |
| NDUFS8NADH:ubiquinone oxidoreductase core subunit S8 | Always | In 1 condition |
| NGLY1N-glycanase 1 | Always | In 2 conditions |
| NOTCH3notch receptor 3 | Always | In 1 condition |
| PIGAphosphatidylinositol glycan anchor biosynthesis class A | Always | In 1 condition |
| PLA2G6phospholipase A2 group VI | Always | In 1 condition |
| RNU4-2RNA, U4 small nuclear 2 | Always | In 1 condition |
| RNU5B-1RNA, U5B small nuclear 1 | Always | In 1 condition |
| SCO2synthesis of cytochrome C oxidase 2 | Always | In 1 condition |
| TEFMtranscription elongation factor, mitochondrial | Always | In 1 condition |
| TSEN54tRNA splicing endonuclease subunit 54 | Always | In 2 conditions |
| UNC13Aunc-13 homolog A | Always | In 1 condition |
| PLP1proteolipid protein 1 | Very often (80–99%) | In 1 condition |
| BCS1LBCS1 ubiquinol-cytochrome c reductase complex chaperone | Often (30–79%) | In 1 condition |
| CHCHD10coiled-coil-helix-coiled-coil-helix domain containing 10 | Often (30–79%) | In 1 condition |
| DTYMKdeoxythymidylate kinase | Often (30–79%) | In 1 condition |
| FUSFUS RNA binding protein | Often (30–79%) | In 1 condition |
| GLSglutaminase | Often (30–79%) | In 1 condition |
| IARS2isoleucyl-tRNA synthetase 2, mitochondrial | Often (30–79%) | In 1 condition |
| KARS1lysyl-tRNA synthetase 1 | Often (30–79%) | In 1 condition |
| KICS2KICSTOR subunit 2 | Often (30–79%) | In 1 condition |
| LONP1lon peptidase 1, mitochondrial | Often (30–79%) | In 1 condition |
| PDHA1pyruvate dehydrogenase E1 subunit alpha 1 | Often (30–79%) | In 1 condition |
| POLGDNA polymerase gamma, catalytic subunit | Often (30–79%) | In 1 condition |
| RANBP2RAN binding protein 2 | Often (30–79%) | In 2 conditions |
| SQSTM1sequestosome 1 | Often (30–79%) | In 1 condition |
| TARDBPTAR DNA binding protein | Often (30–79%) | In 1 condition |
| TBK1TANK binding kinase 1 | Often (30–79%) | In 1 condition |
| VCPvalosin containing protein | Often (30–79%) | In 1 condition |
| ADNPactivity dependent neuroprotector homeobox | Sometimes (5–29%) | In 1 condition |
| AKT3AKT serine/threonine kinase 3 | Sometimes (5–29%) | In 1 condition |
| CYP27A1cytochrome P450 family 27 subfamily A member 1 | Sometimes (5–29%) | In 1 condition |
| DNAJC13DnaJ heat shock protein family (Hsp40) member C13 | Sometimes (5–29%) | In 1 condition |
| DYRK1Adual specificity tyrosine phosphorylation regulated kinase 1A | Sometimes (5–29%) | In 1 condition |
Show 51 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| EIF4G1eukaryotic translation initiation factor 4 gamma 1 | Sometimes (5–29%) | In 1 condition |
| GBA1glucosylceramidase beta 1 | Sometimes (5–29%) | In 1 condition |
| GIGYF2GRB10 interacting GYF protein 2 | Sometimes (5–29%) | In 1 condition |
| KDM3Blysine demethylase 3B | Sometimes (5–29%) | In 1 condition |
| LRRK2leucine rich repeat kinase 2 | Sometimes (5–29%) | In 1 condition |
| MTORmechanistic target of rapamycin kinase | Sometimes (5–29%) | In 1 condition |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Sometimes (5–29%) | In 1 condition |
| PRNPprion protein (Kanno blood group) | Sometimes (5–29%) | In 2 conditions |
| SNCAsynuclein alpha | Sometimes (5–29%) | In 2 conditions |
| THOC2THO complex subunit 2 | Sometimes (5–29%) | In 2 conditions |
| VPS35VPS35 retromer complex component | Sometimes (5–29%) | In 1 condition |
| YY1YY1 transcription factor | Sometimes (5–29%) | In 1 condition |
| EHMT1euchromatic histone lysine methyltransferase 1 | Rarely (1–4%) | In 1 condition |
| KMT2Clysine methyltransferase 2C | Rarely (1–4%) | In 1 condition |
| AP4M1adaptor related protein complex 4 subunit mu 1 | Not recorded | In 1 condition |
| ARXaristaless related homeobox | Not recorded | In 1 condition |
| ATXN3ataxin 3 | Not recorded | In 1 condition |
| AVParginine vasopressin | Not recorded | In 1 condition |
| BRAT1BRCA1 associated ATM activator 1 | Not recorded | In 1 condition |
| C9orf72C9orf72-SMCR8 complex subunit | Not recorded | In 1 condition |
| COX15cytochrome c oxidase assembly factor COX15 | Not recorded | In 1 condition |
| CSF1Rcolony stimulating factor 1 receptor | Not recorded | In 1 condition |
| EIF2B1eukaryotic translation initiation factor 2B subunit alpha | Not recorded | In 1 condition |
| ETFAelectron transfer flavoprotein subunit alpha | Not recorded | In 1 condition |
| ETFBelectron transfer flavoprotein subunit beta | Not recorded | In 1 condition |
| ETFDHelectron transfer flavoprotein dehydrogenase | Not recorded | In 1 condition |
| FARS2phenylalanyl-tRNA synthetase 2, mitochondrial | Not recorded | In 1 condition |
| GRNgranulin precursor | Not recorded | In 1 condition |
| HSD17B4hydroxysteroid 17-beta dehydrogenase 4 | Not recorded | In 1 condition |
| HTThuntingtin | Not recorded | In 1 condition |
| KCNT1potassium sodium-activated channel subfamily T member 1 | Not recorded | In 1 condition |
| L2HGDHL-2-hydroxyglutarate dehydrogenase | Not recorded | In 1 condition |
| LRPPRCleucine rich pentatricopeptide repeat containing | Not recorded | In 1 condition |
| MAN2B1mannosidase alpha class 2B member 1 | Not recorded | In 1 condition |
| MAPTmicrotubule associated protein tau | Not recorded | In 2 conditions |
| MOCS1molybdenum cofactor synthesis 1 | Not recorded | In 1 condition |
| MOCS2molybdenum cofactor synthesis 2 | Not recorded | In 1 condition |
| NARS2asparaginyl-tRNA synthetase 2, mitochondrial | Not recorded | In 1 condition |
| NAXDNAD(P)HX dehydratase | Not recorded | In 1 condition |
| PAX2paired box 2 | Not recorded | In 1 condition |
| PMPCApeptidase, mitochondrial processing subunit alpha | Not recorded | In 1 condition |
| PSEN1presenilin 1 | Not recorded | In 1 condition |
| SERPINI1serpin family I member 1 | Not recorded | In 1 condition |
| TBCDtubulin folding cofactor D | Not recorded | In 1 condition |
| TBPTATA-box binding protein | Not recorded | In 1 condition |
| TFGtrafficking from ER to golgi regulator | Not recorded | In 1 condition |
| TLR3toll like receptor 3 | Not recorded | In 1 condition |
| TREM2triggering receptor expressed on myeloid cells 2 | Not recorded | In 1 condition |
| TYROBPtransmembrane immune signaling adaptor TYROBP | Not recorded | In 1 condition |
| UBQLN2ubiquilin 2 | Not recorded | In 1 condition |
| ZNF335zinc finger protein 335 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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