Trait
Disturbances of consciousness
Clinical name: Reduced consciousness
Abnormally diminished level of attention, responsiveness, or wakefulness.
Summary
- Also called
- Lowered consciousness, Reduced consciousness/confusion
- Body system
- Abnormality of the nervous system
Reference genomeGRCh38hg38
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Get my Genome Test37 genes linked to Disturbances of consciousness
Changes in these genes cause rare conditions in which Disturbances of consciousness is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ABCB1ATP binding cassette subfamily B member 1 | Always | In 1 condition |
| ATP1A3ATPase Na+/K+ transporting subunit alpha 3 | Always | In 1 condition |
| TBK1TANK binding kinase 1 | Very often (80–99%) | In 1 condition |
| TICAM1TIR domain containing adaptor molecule 1 | Very often (80–99%) | In 1 condition |
| TLR3toll like receptor 3 | Very often (80–99%) | In 1 condition |
| TRAF3TNF receptor associated factor 3 | Very often (80–99%) | In 1 condition |
| UNC93B1unc-93B1 regulator of TLR signaling | Very often (80–99%) | In 1 condition |
| ACAT1acetyl-CoA acetyltransferase 1 | Often (30–79%) | In 1 condition |
| CST3cystatin C | Often (30–79%) | In 1 condition |
| MEN1menin 1 | Often (30–79%) | In 1 condition |
| SMARCB1SWI/SNF related BAF chromatin remodeling complex subunit B1 | Often (30–79%) | In 1 condition |
| YY1YY1 transcription factor | Often (30–79%) | In 1 condition |
| CASRcalcium sensing receptor | Sometimes (5–29%) | In 1 condition |
| FBP1fructose-bisphosphatase 1 | Sometimes (5–29%) | In 1 condition |
| GNA11G protein subunit alpha 11 | Sometimes (5–29%) | In 1 condition |
| HLA-Bmajor histocompatibility complex, class I, B | Sometimes (5–29%) | In 1 condition |
| IL12Binterleukin 12B | Sometimes (5–29%) | In 1 condition |
| IRAK1interleukin 1 receptor associated kinase 1 | Sometimes (5–29%) | In 1 condition |
| MLXMAX dimerization protein MLX | Sometimes (5–29%) | In 1 condition |
| MT-CO1mitochondrially encoded cytochrome c oxidase I | Sometimes (5–29%) | In 1 condition |
| MT-CO2mitochondrially encoded cytochrome c oxidase II | Sometimes (5–29%) | In 1 condition |
| MT-CO3mitochondrially encoded cytochrome c oxidase III | Sometimes (5–29%) | In 1 condition |
| MT-ND1mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 | Sometimes (5–29%) | In 1 condition |
| MT-ND4mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 | Sometimes (5–29%) | In 1 condition |
| MT-ND5mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 | Sometimes (5–29%) | In 1 condition |
| MT-ND6mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 | Sometimes (5–29%) | In 1 condition |
| MT-TFmitochondrially encoded tRNA-Phe (UUU/C) | Sometimes (5–29%) | In 1 condition |
| MT-THmitochondrially encoded tRNA-His (CAU/C) | Sometimes (5–29%) | In 1 condition |
| MT-TL1mitochondrially encoded tRNA-Leu (UUA/G) 1 | Sometimes (5–29%) | In 1 condition |
| MT-TQmitochondrially encoded tRNA-Gln (CAA/G) | Sometimes (5–29%) | In 1 condition |
| MT-TS1mitochondrially encoded tRNA-Ser (UCN) 1 | Sometimes (5–29%) | In 1 condition |
| MT-TS2mitochondrially encoded tRNA-Ser (AGU/C) 2 | Sometimes (5–29%) | In 1 condition |
| MT-TWmitochondrially encoded tRNA-Trp (UGA/G) | Sometimes (5–29%) | In 1 condition |
| MYD88MYD88 innate immune signal transduction adaptor | Sometimes (5–29%) | In 1 condition |
| SAT1spermidine/spermine N1-acetyltransferase 1 | Sometimes (5–29%) | In 1 condition |
| SPP1secreted phosphoprotein 1 | Sometimes (5–29%) | In 1 condition |
| STAT4signal transducer and activator of transcription 4 | Sometimes (5–29%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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