Trait
Toe walking
Clinical name: Tip-toe gait
An abnormal gait pattern characterized by the failure of the heel to contact the floor at the onset of stance during gait.
Summary
- Also called
- Walking on tiptoes, Tiptoe gait
- Body system
- Abnormality of the nervous system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test97 genes linked to Toe walking
Changes in these genes cause rare conditions in which Toe walking is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| COASYCoenzyme A synthase | Always | In 1 condition |
| COL6A1collagen type VI alpha 1 chain | Always | In 1 condition |
| DMDdystrophin | Always | In 2 conditions |
| DYNC1H1dynein cytoplasmic 1 heavy chain 1 | Always | In 1 condition |
| FDXRferredoxin reductase | Always | In 1 condition |
| ITPR3inositol 1,4,5-trisphosphate receptor type 3 | Always | In 1 condition |
| JKAMPJNK1/MAPK8 associated membrane protein | Always | In 1 condition |
| KDM2Blysine demethylase 2B | Always | In 1 condition |
| KIDINS220kinase D interacting substrate 220 | Always | In 1 condition |
| MYH7myosin heavy chain 7 | Always | In 1 condition |
| NT5C25'-nucleotidase, cytosolic II | Always | In 1 condition |
| PNPLA8patatin like domain 8, phospholipase A2 | Always | In 1 condition |
| RFC4replication factor C subunit 4 | Always | In 1 condition |
| RTN2reticulon 2 | Always | In 1 condition |
| TAF4TATA-box binding protein associated factor 4 | Always | In 1 condition |
| ADSS1adenylosuccinate synthase 1 | Often (30–79%) | In 1 condition |
| AIFM1apoptosis inducing factor mitochondria associated 1 | Often (30–79%) | In 1 condition |
| ALS2alsin Rho guanine nucleotide exchange factor ALS2 | Often (30–79%) | In 2 conditions |
| AP5Z1adaptor related protein complex 5 subunit zeta 1 | Often (30–79%) | In 1 condition |
| ARSAarylsulfatase A | Often (30–79%) | In 1 condition |
| BAG3BAG cochaperone 3 | Often (30–79%) | In 1 condition |
| CAPN3calpain 3 | Often (30–79%) | In 1 condition |
| CRPPACDP-L-ribitol pyrophosphorylase A | Often (30–79%) | In 1 condition |
| CYP2U1cytochrome P450 family 2 subfamily U member 1 | Often (30–79%) | In 2 conditions |
| DEAF1DEAF1 transcription factor | Often (30–79%) | In 1 condition |
| EMDemerin | Often (30–79%) | In 1 condition |
| ERLIN1ER lipid raft associated 1 | Often (30–79%) | In 3 conditions |
| FHL1four and a half LIM domains 1 | Often (30–79%) | In 1 condition |
| FKRPfukutin related protein | Often (30–79%) | In 3 conditions |
| FKTNfukutin | Often (30–79%) | In 1 condition |
| GJB1gap junction protein beta 1 | Often (30–79%) | In 1 condition |
| KYkyphoscoliosis peptidase | Often (30–79%) | In 1 condition |
| LMNAlamin A/C | Often (30–79%) | In 2 conditions |
| PANK2pantothenate kinase 2 | Often (30–79%) | In 1 condition |
| PI4KAphosphatidylinositol 4-kinase alpha | Often (30–79%) | In 1 condition |
| PLAAT3phospholipase A and acyltransferase 3 | Often (30–79%) | In 1 condition |
| POMT1protein O-mannosyltransferase 1 | Often (30–79%) | In 1 condition |
| PSAPprosaposin | Often (30–79%) | In 1 condition |
| RAI1retinoic acid induced 1 | Often (30–79%) | In 1 condition |
| REEP2receptor accessory protein 2 | Often (30–79%) | In 1 condition |
Show 57 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| SGCAsarcoglycan alpha | Often (30–79%) | In 1 condition |
| SLC39A14solute carrier family 39 member 14 | Often (30–79%) | In 1 condition |
| SMG8SMG8 nonsense mediated mRNA decay factor | Often (30–79%) | In 1 condition |
| SPTLC1serine palmitoyltransferase long chain base subunit 1 | Often (30–79%) | In 2 conditions |
| SYNE1spectrin repeat containing nuclear envelope protein 1 | Often (30–79%) | In 2 conditions |
| SYNE2spectrin repeat containing nuclear envelope protein 2 | Often (30–79%) | In 1 condition |
| TMEM43transmembrane protein 43 | Often (30–79%) | In 1 condition |
| AASSaminoadipate-semialdehyde synthase | Sometimes (5–29%) | In 1 condition |
| ADAMTSL2ADAMTS like 2 | Sometimes (5–29%) | In 1 condition |
| ALDH18A1aldehyde dehydrogenase 18 family member A1 | Sometimes (5–29%) | In 1 condition |
| ATL1atlastin GTPase 1 | Sometimes (5–29%) | In 1 condition |
| ATP13A2ATPase cation transporting 13A2 | Sometimes (5–29%) | In 1 condition |
| COL12A1collagen type XII alpha 1 chain | Sometimes (5–29%) | In 1 condition |
| DDHD2DDHD domain containing 2 | Sometimes (5–29%) | In 1 condition |
| DYSFdysferlin | Sometimes (5–29%) | In 3 conditions |
| FBN1fibrillin 1 | Sometimes (5–29%) | In 2 conditions |
| FUSFUS RNA binding protein | Sometimes (5–29%) | In 1 condition |
| GFM2GTP dependent ribosome recycling factor mitochondrial 2 | Sometimes (5–29%) | In 1 condition |
| GNB2G protein subunit beta 2 | Sometimes (5–29%) | In 1 condition |
| GNEglucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | Sometimes (5–29%) | In 1 condition |
| GNPTABN-acetylglucosamine-1-phosphate transferase subunits alpha and beta | Sometimes (5–29%) | In 1 condition |
| H4C5H4 clustered histone 5 | Sometimes (5–29%) | In 1 condition |
| HADHAhydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha | Sometimes (5–29%) | In 1 condition |
| HADHBhydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta | Sometimes (5–29%) | In 1 condition |
| HARS1histidyl-tRNA synthetase 1 | Sometimes (5–29%) | In 1 condition |
| KCNA1potassium voltage-gated channel subfamily A member 1 | Sometimes (5–29%) | In 1 condition |
| KIF1Ckinesin family member 1C | Sometimes (5–29%) | In 1 condition |
| LMX1BLIM homeobox transcription factor 1 beta | Sometimes (5–29%) | In 1 condition |
| LTBP3latent transforming growth factor beta binding protein 3 | Sometimes (5–29%) | In 1 condition |
| MORC2MORC family CW-type zinc finger 2 | Sometimes (5–29%) | In 1 condition |
| MT-TEmitochondrially encoded tRNA-Glu (GAA/G) | Sometimes (5–29%) | In 1 condition |
| MYPNmyopalladin | Sometimes (5–29%) | In 1 condition |
| PEX16peroxisomal biogenesis factor 16 | Sometimes (5–29%) | In 1 condition |
| RNU5B-1RNA, U5B small nuclear 1 | Sometimes (5–29%) | In 1 condition |
| SBF2SET binding factor 2 | Sometimes (5–29%) | In 1 condition |
| SGCGsarcoglycan gamma | Sometimes (5–29%) | In 1 condition |
| SIGMAR1sigma receptor chaperone 1 | Sometimes (5–29%) | In 1 condition |
| SORDsorbitol dehydrogenase | Sometimes (5–29%) | In 1 condition |
| SPG11SPG11 vesicle trafficking associated, spatacsin | Sometimes (5–29%) | In 2 conditions |
| SPTLC2serine palmitoyltransferase long chain base subunit 2 | Sometimes (5–29%) | In 1 condition |
| TARDBPTAR DNA binding protein | Sometimes (5–29%) | In 1 condition |
| TNNT1troponin T1, slow skeletal type | Sometimes (5–29%) | In 1 condition |
| TPM2tropomyosin 2 | Sometimes (5–29%) | In 2 conditions |
| TPM3tropomyosin 3 | Sometimes (5–29%) | In 1 condition |
| TRMT2BtRNA methyltransferase 2B | Sometimes (5–29%) | In 1 condition |
| UBQLN2ubiquilin 2 | Sometimes (5–29%) | In 1 condition |
| UGGT1UDP-glucose glycoprotein glucosyltransferase 1 | Sometimes (5–29%) | In 1 condition |
| VCPvalosin containing protein | Sometimes (5–29%) | In 1 condition |
| YY1YY1 transcription factor | Sometimes (5–29%) | In 1 condition |
| KDM6Blysine demethylase 6B | Rarely (1–4%) | In 1 condition |
| SPTBN1spectrin beta, non-erythrocytic 1 | Rarely (1–4%) | In 1 condition |
| B4GALNT1beta-1,4-N-acetyl-galactosaminyltransferase 1 | Not recorded | In 1 condition |
| BICD2BICD cargo adaptor 2 | Not recorded | In 1 condition |
| INPP5Kinositol polyphosphate-5-phosphatase K | Not recorded | In 1 condition |
| KMT2Blysine methyltransferase 2B | Not recorded | In 1 condition |
| LRSAM1leucine rich repeat and sterile alpha motif containing 1 | Not recorded | In 1 condition |
| TLK2tousled like kinase 2 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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