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Trait
Underdeveloped breasts
Clinical name: Breast hypoplasia
Underdevelopment of the breast.
Summary
- Body system
- Abnormality of the breast
Underdeveloped breastsHP:0003187
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Read the genes linked to Underdeveloped breasts, and the rest of your genome, with one test.
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Get my Genome Test44 genes linked to Underdeveloped breasts
Changes in these genes cause rare conditions in which Underdeveloped breasts is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ORC1origin recognition complex subunit 1 | Always | In 1 condition |
| ORC4origin recognition complex subunit 4 | Always | In 1 condition |
| ORC6origin recognition complex subunit 6 | Always | In 1 condition |
| TBX3T-box transcription factor 3 | Always | In 1 condition |
| CHD7chromodomain helicase DNA binding protein 7 | Very often (80–99%) | In 2 conditions |
| DUSP6dual specificity phosphatase 6 | Very often (80–99%) | In 2 conditions |
| EMX2empty spiracles homeobox 2 | Very often (80–99%) | In 2 conditions |
| ESR1estrogen receptor 1 | Very often (80–99%) | In 1 condition |
| FGF17fibroblast growth factor 17 | Very often (80–99%) | In 2 conditions |
| FGF8fibroblast growth factor 8 | Very often (80–99%) | In 2 conditions |
| FGFR1fibroblast growth factor receptor 1 | Very often (80–99%) | In 2 conditions |
| GNRH1gonadotropin releasing hormone 1 | Very often (80–99%) | In 1 condition |
| GNRHRgonadotropin releasing hormone receptor | Very often (80–99%) | In 1 condition |
| HS6ST1heparan sulfate 6-O-sulfotransferase 1 | Very often (80–99%) | In 2 conditions |
| KISS1KiSS-1 metastasis suppressor | Very often (80–99%) | In 1 condition |
| KISS1RKISS1 receptor | Very often (80–99%) | In 1 condition |
| NHLH2nescient helix-loop-helix 2 | Very often (80–99%) | In 1 condition |
| NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor | Very often (80–99%) | In 1 condition |
| PROK2prokineticin 2 | Very often (80–99%) | In 2 conditions |
| PROKR2prokineticin receptor 2 | Very often (80–99%) | In 2 conditions |
| SPRY4sprouty RTK signaling antagonist 4 | Very often (80–99%) | In 2 conditions |
| TAC3tachykinin precursor 3 | Very often (80–99%) | In 1 condition |
| TACR3tachykinin receptor 3 | Very often (80–99%) | In 2 conditions |
| WDR11WD repeat domain 11 | Very often (80–99%) | In 2 conditions |
| ANOS1anosmin 1 | Often (30–79%) | In 1 condition |
| CCDC141coiled-coil domain containing 141 | Often (30–79%) | In 1 condition |
| DCCDCC netrin 1 receptor | Often (30–79%) | In 1 condition |
| FEZF1FEZ family zinc finger 1 | Often (30–79%) | In 1 condition |
| FLRT3fibronectin leucine rich transmembrane protein 3 | Often (30–79%) | In 1 condition |
| HESX1HESX homeobox 1 | Often (30–79%) | In 1 condition |
| IL17RDinterleukin 17 receptor D | Often (30–79%) | In 1 condition |
| NDNFneuron derived neurotrophic factor | Often (30–79%) | In 1 condition |
| SEMA3Asemaphorin 3A | Often (30–79%) | In 1 condition |
| SOX10SRY-box transcription factor 10 | Often (30–79%) | In 1 condition |
| TP63tumor protein p63 | Often (30–79%) | In 2 conditions |
| TWIST2twist family bHLH transcription factor 2 | Often (30–79%) | In 1 condition |
| LEF1lymphoid enhancer binding factor 1 | Sometimes (5–29%) | In 1 condition |
| MAFMAF bZIP transcription factor | Sometimes (5–29%) | In 1 condition |
| POC1APOC1 centriolar protein A | Sometimes (5–29%) | In 1 condition |
| YY1YY1 transcription factor | Sometimes (5–29%) | In 1 condition |
Show 4 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| ANTXR1ANTXR cell adhesion molecule 1 | Not recorded | In 1 condition |
| CDT1chromatin licensing and DNA replication factor 1 | Not recorded | In 1 condition |
| EFNB1ephrin B1 | Not recorded | In 1 condition |
| IKBKGinhibitor of nuclear factor kappa B kinase regulatory subunit gamma | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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