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Gene

PODXL

podocalyxin like

Summary

Cytogenetic location
7q32.3
Coordinates
Chromosome 7: 131,500,271–131,556,628 (GRCh38)
Exons
9 exons across 56.4 kb
Protein
558 amino acids
Also known as
PCLP, Gp200, PC, PODXL1, PDX, gp135
MANE Select transcript
ENST00000378555.8NM_001018111.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

  • Nephrotic Syndrome

    • Nephrosis

      Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA.

      • 1 GenCC submitter rates it definitive or strong

How PODXL is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 7, with a bracket where PODXL sits. PODXL and 1 gene near it on chromosome 7, from 131,028,450 to 132,028,449.Chromosome 77q32.3p22.3p22.2p22.1p21.3p21.2p21.1p15.3p15.2p15.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.21q11.22q11.23q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q31.1q31.2q31.31q31.32q31.33q32.1q32.2q32.3q33q34q35q36.1q36.2q36.3131.2 Mb131.4 Mb131.6 Mb131.8 Mb132 MbMKLN1: 131,110,096–131,496,632, forward strandMKLN1PODXL: 131,500,271–131,556,628, reverse strandPODXLDiagram of PODXL: 9 exons on the reverse strand of chromosome 7Exon 9: 131,500,271–131,504,508, 4,238 basesExon 8: 131,505,868–131,506,035, 168 basesExon 7: 131,506,260–131,506,321, 62 basesExon 6: 131,506,579–131,506,726, 148 basesExon 5: 131,508,951–131,509,028, 78 basesExon 4: 131,509,365–131,509,585, 221 basesExon 3: 131,510,236–131,510,331, 96 basesExon 2: 131,510,828–131,511,433, 606 basesExon 1: 131,556,260–131,556,628, 369 bases9515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 6 kb of the gene's 56.4 kb; 1,677 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). PODXL gene: podocalyxin like. Retrieved 17 October 2026, from https://dantelabs.com/genes/podxl

Vancouver

Dante Labs. PODXL gene: podocalyxin like [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/podxl

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