Trait
Male sexual dysfunction
A problem occurring during any phase of the male sexual response cycle that prevents the individual from experiencing satisfaction from the sexual activity
Summary
- Body system
- Abnormality of the genitourinary system
Reference genomeGRCh38hg38
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Get my Genome Test23 genes linked to Male sexual dysfunction
Changes in these genes cause rare conditions in which Male sexual dysfunction is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ARandrogen receptor | Very often (80–99%) | In 1 condition |
| ABCD1ATP binding cassette subfamily D member 1 | Often (30–79%) | In 1 condition |
| CTSHcathepsin H | Often (30–79%) | In 1 condition |
| HCRThypocretin neuropeptide precursor | Often (30–79%) | In 1 condition |
| HLA-DQB1major histocompatibility complex, class II, DQ beta 1 | Often (30–79%) | In 1 condition |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Often (30–79%) | In 1 condition |
| MOGmyelin oligodendrocyte glycoprotein | Often (30–79%) | In 1 condition |
| P2RY11purinergic receptor P2Y11 | Often (30–79%) | In 1 condition |
| RTN2reticulon 2 | Often (30–79%) | In 1 condition |
| TNFSF4TNF superfamily member 4 | Often (30–79%) | In 1 condition |
| UBAP1ubiquitin associated protein 1 | Often (30–79%) | In 1 condition |
| ZNF365zinc finger protein 365 | Often (30–79%) | In 1 condition |
| DNAJC6DnaJ heat shock protein family (Hsp40) member C6 | Sometimes (5–29%) | In 1 condition |
| HTRA2HtrA serine peptidase 2 | Sometimes (5–29%) | In 1 condition |
| LRRK2leucine rich repeat kinase 2 | Sometimes (5–29%) | In 1 condition |
| PARK7Parkinsonism associated deglycase | Sometimes (5–29%) | In 1 condition |
| PINK1PTEN induced kinase 1 | Sometimes (5–29%) | In 1 condition |
| PODXLpodocalyxin like | Sometimes (5–29%) | In 1 condition |
| PRKNparkin RBR E3 ubiquitin protein ligase | Sometimes (5–29%) | In 1 condition |
| SNCAsynuclein alpha | Sometimes (5–29%) | In 1 condition |
| SYNJ1synaptojanin 1 | Sometimes (5–29%) | In 1 condition |
| UCHL1ubiquitin C-terminal hydrolase L1 | Sometimes (5–29%) | In 1 condition |
| VPS13Cvacuolar protein sorting 13 homolog C | Sometimes (5–29%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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