Trait
Double vision
Clinical name: Diplopia
Diplopia is a condition in which a single object is perceived as two images, it is also known as double vision.
Summary
- Body system
- Abnormality of the eye
Reference genomeGRCh38hg38
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Get my Genome Test78 genes linked to Double vision
Changes in these genes cause rare conditions in which Double vision is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ABCB1ATP binding cassette subfamily B member 1 | Always | In 1 condition |
| POLGDNA polymerase gamma, catalytic subunit | Always | In 3 conditions |
| RAB3ARAB3A, member RAS oncogene family | Always | In 1 condition |
| RFC4replication factor C subunit 4 | Always | In 1 condition |
| SDHAsuccinate dehydrogenase complex flavoprotein subunit A | Always | In 1 condition |
| TOP3ADNA topoisomerase III alpha | Always | In 1 condition |
| TYMPthymidine phosphorylase | Always | In 1 condition |
| MYO5Amyosin VA | Very often (80–99%) | In 1 condition |
| ATP1A2ATPase Na+/K+ transporting subunit alpha 2 | Often (30–79%) | In 2 conditions |
| ATXN3ataxin 3 | Often (30–79%) | In 4 conditions |
| CACNA1Acalcium voltage-gated channel subunit alpha1 A | Often (30–79%) | In 4 conditions |
| DNAJC13DnaJ heat shock protein family (Hsp40) member C13 | Often (30–79%) | In 1 condition |
| EIF4G1eukaryotic translation initiation factor 4 gamma 1 | Often (30–79%) | In 1 condition |
| ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit | Often (30–79%) | In 1 condition |
| ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit | Often (30–79%) | In 1 condition |
| ERCC4ERCC excision repair 4, endonuclease catalytic subunit | Often (30–79%) | In 1 condition |
| ERCC5ERCC excision repair 5, endonuclease | Often (30–79%) | In 1 condition |
| FGF14fibroblast growth factor 14 | Often (30–79%) | In 1 condition |
| GBA1glucosylceramidase beta 1 | Often (30–79%) | In 1 condition |
| GIGYF2GRB10 interacting GYF protein 2 | Often (30–79%) | In 1 condition |
| KCNA1potassium voltage-gated channel subfamily A member 1 | Often (30–79%) | In 1 condition |
| LRRK2leucine rich repeat kinase 2 | Often (30–79%) | In 2 conditions |
| PRRT2proline rich transmembrane protein 2 | Often (30–79%) | In 1 condition |
| RILPL1Rab interacting lysosomal protein like 1 | Often (30–79%) | In 1 condition |
| RTN2reticulon 2 | Often (30–79%) | In 1 condition |
| SAMD9Lsterile alpha motif domain containing 9 like | Often (30–79%) | In 1 condition |
| SCN1Asodium voltage-gated channel alpha subunit 1 | Often (30–79%) | In 1 condition |
| SLC2A1solute carrier family 2 member 1 | Often (30–79%) | In 2 conditions |
| SNCAsynuclein alpha | Often (30–79%) | In 2 conditions |
| TPP1tripeptidyl peptidase 1 | Often (30–79%) | In 2 conditions |
| VPS35VPS35 retromer complex component | Often (30–79%) | In 1 condition |
| ADPRSADP-ribosylserine hydrolase | Sometimes (5–29%) | In 1 condition |
| AIPAHR interacting HSP90 co-chaperone | Sometimes (5–29%) | In 1 condition |
| ANO10anoctamin 10 | Sometimes (5–29%) | In 1 condition |
| CACNA1Gcalcium voltage-gated channel subunit alpha1 G | Sometimes (5–29%) | In 2 conditions |
| CDH23cadherin related 23 | Sometimes (5–29%) | In 2 conditions |
| DKK1dickkopf Wnt signaling pathway inhibitor 1 | Sometimes (5–29%) | In 1 condition |
| HLA-Bmajor histocompatibility complex, class I, B | Sometimes (5–29%) | In 1 condition |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Sometimes (5–29%) | In 2 conditions |
| KCND3potassium voltage-gated channel subfamily D member 3 | Sometimes (5–29%) | In 1 condition |
Show 38 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| MEN1menin 1 | Sometimes (5–29%) | In 1 condition |
| NF2NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor | Sometimes (5–29%) | In 2 conditions |
| NFKB2nuclear factor kappa B subunit 2 | Sometimes (5–29%) | In 1 condition |
| NPTX1neuronal pentraxin 1 | Sometimes (5–29%) | In 1 condition |
| P4HA2prolyl 4-hydroxylase subunit alpha 2 | Sometimes (5–29%) | In 1 condition |
| PRNPprion protein (Kanno blood group) | Sometimes (5–29%) | In 2 conditions |
| PTPN22protein tyrosine phosphatase non-receptor type 22 | Sometimes (5–29%) | In 1 condition |
| SCN4Asodium voltage-gated channel alpha subunit 4 | Sometimes (5–29%) | In 1 condition |
| SH3TC2SH3 domain and tetratricopeptide repeats 2 | Sometimes (5–29%) | In 1 condition |
| SLC1A3solute carrier family 1 member 3 | Sometimes (5–29%) | In 2 conditions |
| SPTBN2spectrin beta, non-erythrocytic 2 | Sometimes (5–29%) | In 1 condition |
| TMEM240transmembrane protein 240 | Sometimes (5–29%) | In 1 condition |
| TTC19tetratricopeptide repeat domain 19 | Sometimes (5–29%) | In 1 condition |
| TTRtransthyretin | Sometimes (5–29%) | In 1 condition |
| DARS2aspartyl-tRNA synthetase 2, mitochondrial | Rarely (1–4%) | In 1 condition |
| DNAJC6DnaJ heat shock protein family (Hsp40) member C6 | Rarely (1–4%) | In 1 condition |
| GRK1G protein-coupled receptor kinase 1 | Rarely (1–4%) | In 1 condition |
| HTRA2HtrA serine peptidase 2 | Rarely (1–4%) | In 1 condition |
| NAB2NGFI-A binding protein 2 | Rarely (1–4%) | In 1 condition |
| NOP56NOP56 ribonucleoprotein | Rarely (1–4%) | In 1 condition |
| PARK7Parkinsonism associated deglycase | Rarely (1–4%) | In 1 condition |
| PINK1PTEN induced kinase 1 | Rarely (1–4%) | In 1 condition |
| PODXLpodocalyxin like | Rarely (1–4%) | In 1 condition |
| PRKNparkin RBR E3 ubiquitin protein ligase | Rarely (1–4%) | In 1 condition |
| SAGS-antigen visual arrestin | Rarely (1–4%) | In 1 condition |
| STAT6signal transducer and activator of transcription 6 | Rarely (1–4%) | In 1 condition |
| SYNJ1synaptojanin 1 | Rarely (1–4%) | In 1 condition |
| UCHL1ubiquitin C-terminal hydrolase L1 | Rarely (1–4%) | In 1 condition |
| VPS13Cvacuolar protein sorting 13 homolog C | Rarely (1–4%) | In 1 condition |
| HLA-DQB1major histocompatibility complex, class II, DQ beta 1 | Not recorded | In 1 condition |
| MAPTmicrotubule associated protein tau | Not recorded | In 1 condition |
| MGME1mitochondrial genome maintenance exonuclease 1 | Not recorded | In 1 condition |
| MT-TL1mitochondrially encoded tRNA-Leu (UUA/G) 1 | Not recorded | In 1 condition |
| MT-TL2mitochondrially encoded tRNA-Leu (CUN) 2 | Not recorded | In 1 condition |
| MT-TNmitochondrially encoded tRNA-Asn (AAU/C) | Not recorded | In 1 condition |
| MT-TS1mitochondrially encoded tRNA-Ser (UCN) 1 | Not recorded | In 1 condition |
| SERPINI1serpin family I member 1 | Not recorded | In 1 condition |
| TGFB1transforming growth factor beta 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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