Gene
DAAM2
dishevelled associated activator of morphogenesis 2
- HGNC 18143(opens in a new tab)
- Ensembl gene ENSG00000146122(opens in a new tab)
- NCBI Gene 23500(opens in a new tab)
Summary
- Cytogenetic location
- 6p21.2
- Coordinates
- Chromosome 6: 39,792,376–39,904,869 (GRCh38)
- Exons
- 25 exons across 112.5 kb
- Protein
- 1,068 amino acids
- Also known as
- KIAA0381, NPHS24
- MANE Select transcript
- ENST00000274867.9NM_001201427.2
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read DAAM2, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome TestCurated report relevant to this gene
Nephrotic Syndrome
- Nephrosis
Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA.
- 2 GenCC submitters rate it definitive or strong
How DAAM2 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 6.2 kb of the gene's 112.5 kb; 3,207 of those bases code for the protein.
How a genome test reads DAAM2
4
positions in DAAM2 where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 112.5 kb of DAAM2, introns included, not only the 6.2 kb of exons.
Traits linked to DAAM2
The Human Phenotype Ontology lists these as features of the rare conditions DAAM2 can cause. Each trait's page lists the other genes linked to it.
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
- The ACMG secondary findings list, SF v3.2.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). DAAM2 gene: dishevelled associated activator of morphogenesis 2. Retrieved 16 October 2026, from https://dantelabs.com/genes/daam2
Dante Labs. DAAM2 gene: dishevelled associated activator of morphogenesis 2 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/daam2
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks