Trait
Akinesia
Inability to initiate changes in activity or movement and to perform ordinary volitional movements rapidly and easily.
Summary
- Body system
- Abnormality of the nervous system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test43 genes linked to Akinesia
Changes in these genes cause rare conditions in which Akinesia is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| DCTN1dynactin subunit 1 | Always | In 1 condition |
| KARS1lysyl-tRNA synthetase 1 | Always | In 1 condition |
| MAPTmicrotubule associated protein tau | Always | In 3 conditions |
| NEBnebulin | Always | In 1 condition |
| RAB32RAB32, member RAS oncogene family | Always | In 1 condition |
| TOR1Atorsin family 1 member A | Always | In 1 condition |
| VPS13Cvacuolar protein sorting 13 homolog C | Always | In 1 condition |
| DOK7docking protein 7 | Very often (80–99%) | In 1 condition |
| GLDNgliomedin | Very often (80–99%) | In 1 condition |
| KIF21Akinesin family member 21A | Very often (80–99%) | In 1 condition |
| MAGEL2MAGE family member L2 | Very often (80–99%) | In 1 condition |
| MUSKmuscle associated receptor tyrosine kinase | Very often (80–99%) | In 1 condition |
| MYOD1myogenic differentiation 1 | Very often (80–99%) | In 1 condition |
| NUP88nucleoporin 88 | Very often (80–99%) | In 1 condition |
| RAPSNreceptor associated protein of the synapse | Very often (80–99%) | In 1 condition |
| SLC18A3solute carrier family 18 member A3 | Very often (80–99%) | In 1 condition |
| TUBA1Atubulin alpha 1a | Very often (80–99%) | In 1 condition |
| DNAJC13DnaJ heat shock protein family (Hsp40) member C13 | Often (30–79%) | In 1 condition |
| DNAJC6DnaJ heat shock protein family (Hsp40) member C6 | Often (30–79%) | In 1 condition |
| EIF4G1eukaryotic translation initiation factor 4 gamma 1 | Often (30–79%) | In 1 condition |
| GBA1glucosylceramidase beta 1 | Often (30–79%) | In 2 conditions |
| GIGYF2GRB10 interacting GYF protein 2 | Often (30–79%) | In 1 condition |
| LRRK2leucine rich repeat kinase 2 | Often (30–79%) | In 1 condition |
| NDUFA13NADH:ubiquinone oxidoreductase subunit A13 | Often (30–79%) | In 1 condition |
| NR4A2nuclear receptor subfamily 4 group A member 2 | Often (30–79%) | In 1 condition |
| PODXLpodocalyxin like | Often (30–79%) | In 1 condition |
| SNCAsynuclein alpha | Often (30–79%) | In 1 condition |
| SYNJ1synaptojanin 1 | Often (30–79%) | In 1 condition |
| TMEM240transmembrane protein 240 | Often (30–79%) | In 2 conditions |
| VPS35VPS35 retromer complex component | Often (30–79%) | In 2 conditions |
| WDR45WD repeat domain 45 | Often (30–79%) | In 1 condition |
| CPceruloplasmin | Sometimes (5–29%) | In 1 condition |
| FXR1FMR1 autosomal homolog 1 | Sometimes (5–29%) | In 1 condition |
| PANK2pantothenate kinase 2 | Sometimes (5–29%) | In 1 condition |
| DPAGT1dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 | Rarely (1–4%) | In 1 condition |
| FGF14fibroblast growth factor 14 | Rarely (1–4%) | In 1 condition |
| ATP13A2ATPase cation transporting 13A2 | Not recorded | In 1 condition |
| CHRNA1cholinergic receptor nicotinic alpha 1 subunit | Not recorded | In 1 condition |
| CHRNDcholinergic receptor nicotinic delta subunit | Not recorded | In 1 condition |
| CHRNGcholinergic receptor nicotinic gamma subunit | Not recorded | In 1 condition |
Show 3 more genes
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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